Frontiers in Aging

Original Research

Published on 05 Feb 2026

Unwanted loneliness among older adults in rural areas: associated factors and guidelines for community intervention

in Interventions in Aging

A. Yurrebaso
E. Picado-Valverde
E. García-Valverde
R. Guzmán-Ordaz

Frontiers in Aging

doi 10.3389/fragi.2026.1681481

377 views

Original Research

Accepted on 04 Feb 2026

Cardiovascular Risk Factor Changes Associated with Six-Year Circuit Training in Older Adults: A Retrospective Cohort Analysis

in Interventions in Aging

Marcelo Pereira de Lima
Renata Miyabara
Lujain Khalaf
Shady Salah Bagady
Saed Fawaz Raddawi
Jose Antonio Silva Jr
Luciana Aparecida Campos
Ovidiu Constantin Baltatu

Frontiers in Aging

Review

Published on 04 Feb 2026

Promoting healthy aging in a digital world: leveraging technology for enhanced elderly care and wellbeing

in Interventions in Aging

Patrizio Armeni
Irem Polat
Leonardo Maria De Rossi
Lorenzo Diaferia
Sara De Padova
Athena Gatti
Severino Meregalli

Frontiers in Aging

doi 10.3389/fragi.2026.1687784

519 views

Original Research

Published on 04 Feb 2026

Tensiomyography-derived contractile parameters in sarcopenic and non-sarcopenic older adults

in Musculoskeletal Aging

Katarina Pus
Miloš Kalc
Boštjan Šimunič

Frontiers in Aging

doi 10.3389/fragi.2026.1719152

347 views

Review

Published on 04 Feb 2026

Molecular pathways linking chronic psychological stress to accelerated aging: mechanisms and interventions

in Molecular Mechanisms of Aging

Othman A. Alhazzaa
Hanin M. Abahussin
Majed A. Majrashi
Maryam S. Alotaibi
Mohammad N. Alkhrayef
Ziyad A. Alhamdan
Abdullah O. Alawad

Frontiers in Aging

doi 10.3389/fragi.2026.1743142

684 views

Original Research

Accepted on 03 Feb 2026

Gene–Gene and Gene–Environment Interactions among CYP19A1, ESR1, IL6, IL6R, IL1β, RANK and RANKL variants associated with Osteoporosis and Hip Fracture in Mexican Women

in Genetics, Genomics and Epigenomics of Aging

Antonio Miranda-Duarte
Valeria Ponce de León-Suárez
Alberto Hidalgo Bravo
Rafael Velazquez-Cruz
Esperanza Ramírez-Pérez
O. Celeste Martínez-Ramírez
Clementina Castro-Hernández
Blanca Barredo-Prieto
LEONORA CASAS-AVILA

Frontiers in Aging

Brief Research Report

Accepted on 03 Feb 2026

Obesity and Low Lean Mass Are Associated with Dysregulated IGFBP-3, Inflammatory Biomarkers, and Physical Impairment in Older Adult Women with Frailty

in Musculoskeletal Aging

Alan Lins Fernandes
Rosa Maria Rodrigues Pereira
Valeria de Falco Caparbo
Camila Santos Figueredo
Caroline Freitas Gomes
EDUARDO BORBA
Diogo Souza Domiciano

Frontiers in Aging

Original Research

Published on 02 Feb 2026

Phenotypic and functional heterogeneity of naïve CD8+ T cells in human peripheral blood during aging

in Aging and the Immune System

Luca Pangrazzi
Patrizia Pehl
Lotti Hoffmann
Martin Bachmann
Gabriele Chelini
Michael Keller
Brigitte Jenewein
Maria Cavinato
Birgit Weinberger

Frontiers in Aging

doi 10.3389/fragi.2026.1765665

433 views

Original Research

Published on 02 Feb 2026

Intravenous infusion of nicotinamide adenine dinucleotide (NAD+) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting

in Healthy Longevity

Kirsten Reyna
Greer Heinzen
Nikita Patel
Marie Ritter
Alexandra Siojo
Henry Legere
Rachele Pojednic

Frontiers in Aging

doi 10.3389/fragi.2026.1652582

2,429 views

Original Research

Accepted on 30 Jan 2026

Research hotspots and trends of senolytic therapy: a bibliometric and visualization analysis from 2015 to 2025

in Cellular Senescence

Zitong Feng
Xueying Wang
Yutong Zhou
Run Lin
Bingjie He
Shaoyang Cui
Chunzhi Tang

Frontiers in Aging

221 views

Original Research

Accepted on 30 Jan 2026

PCKP versus UPKP for Moderate-to-Severe Osteoporotic Vertebral Compression Fractures: A Prospective Randomized Controlled Trial Revealing Synergistic Mechanisms of Optimized Bone Cement Distribution and Anti-Osteoporosis Therapy on Medium-to Long-Term Outcomes

in Musculoskeletal Aging

FuGuo Yang

Frontiers in Aging

Original Research

Published on 29 Jan 2026

Periorbital skin index as a biomarker for biological aging and health status

in Healthy Longevity

Ki-Nam Gu
Sangseob Leem
Hanji Kim
Joong-Gon Shin
Jung Yeon Seo
Sunghwan Hwang
Eui Taek Jeong
Yunkwan Kim
Nae Gyu Kang

Frontiers in Aging

doi 10.3389/fragi.2026.1715245

1,367 views

Case Report

Published on 28 Jan 2026

Combined spinal cord stimulation and intrathecal Morphine–Sufentanil therapy for refractory cancer pain: a case report

in Aging and Cancer

Zhi Shan Zhang
Yi Zhang
Jie Wu

Frontiers in Aging

doi 10.3389/fragi.2026.1710432

317 views

Review

Published on 28 Jan 2026

A comprehensive review of artificial intelligence as a catalyst in aging research: insights, gaps and future perspectives

in Interventions in Aging

Tasnuva Binte Mahbub
Parsa Safaeian
Salman Sohrabi

Frontiers in Aging

doi 10.3389/fragi.2026.1644669

591 views

Brief Research Report

Accepted on 27 Jan 2026

Impact of Comorbidities in Patients with Erosive Hand Osteoarthritis (EHOA), a monocentric study

in Musculoskeletal Aging

Sara Bindoli
Giacomo Cozzi
Clarissa Benvoluti
Mariagrazia Lorenzin
Stefania Vio
Paolo Sfriso
Marta Favero
Roberta Ramonda

Frontiers in Aging

132 views

Original Research

Accepted on 27 Jan 2026

Does Time Spent Upright Moderate the Influence of a Weighted Vest on Change in Bone Mineral Density During Weight Loss among Older Adults? A Secondary Analysis of the INVEST in Bone Health Randomized Controlled Trial

in Musculoskeletal Aging

Jason Fanning
Daniel P. Beavers
Shirley M. Bluethmann
S. Delanie Lynch
Ashley A. Weaver
Cassidy Guida
Kristen M. Beavers

Frontiers in Aging

143 views

Systematic Review

Accepted on 27 Jan 2026

Effect of milk and dairy intake on cognitive function in older adults: a systematic review and meta-analysis

in Interventions in Aging

Yessica Giraldo-Castrillon
Juan Diego Mendoza
Marianne Lopez-Cabrera
Jose P Lopez-Lopez
Patricio Lopez-Jaramillo

Frontiers in Aging

170 views

Systematic Review

Accepted on 26 Jan 2026

Non-pharmacological mental health interventions for older adults in México: A systematic review

in Interventions in Aging

María Fernanda Zapata-de la Rosa
Harvey Apolonio-Cortés
Rodrigo Ramirez-Rodriguez
Rafael Fernández-Demeneghi
Angel Puig-Lagunes

Frontiers in Aging

407 views

Review

Accepted on 26 Jan 2026

The Tight Bond Between Fanconi Anemia and Aging

in Genetics, Genomics and Epigenomics of Aging

Marco Antonio Mejía-Barrera
Enya Enara Martínez-Torres
Ulises Juárez
Leda Torres
Moisés Ó Fiesco-Roa
Benilde García de Teresa
Juan Carlos Gómez-Verjan
Jorge Melendez-Zajgla
Alfredo Rodríguez
Silvia Sánchez

Frontiers in Aging

183 views

Editorial

Accepted on 23 Jan 2026

Editorial: Insights in Genetics, Genomics and Epigenomics of Aging:2025

in Genetics, Genomics and Epigenomics of Aging

Marcella Reale

Frontiers in Aging

674 views

Opinion

Published on 22 Jan 2026

Time to stand up faster: underutilization of real-world sit-to-stand transition velocity in aging research

in Healthy Longevity

Myles W. O’Brien

Frontiers in Aging

doi 10.3389/fragi.2026.1639286

1,576 views

Original Research

Published on 22 Jan 2026

Within- and between-individual associations between sleep and cognition in older community-dwelling individuals

in Healthy Longevity

Ciro della Monica
Kiran K. G. Ravindran
Giuseppe Atzori
William Trender
Adam Hampshire
Simon S. Skene
Hana Hassanin
Victoria Revell
Derk-Jan Dijk

Frontiers in Aging

doi 10.3389/fragi.2025.1650312

1,770 views

Original Research

Accepted on 21 Jan 2026

One-month Early Time-Restricted Eating Mitigates Brain Aging and Enhances Memory in Males with Metabolic Syndrome: An MRI Structural Study

in Aging, Metabolism and Redox Biology

Yue Qin
Xiaoshi Li
Lei Wang
Linshuang Feng
Xin Jin
Tingting Qu
Yuying Wang
Bingbing Wu
Juan Tian
Yifan Qian

Frontiers in Aging

164 views

Perspective

Published on 21 Jan 2026

Epigenetic program of ontogenesis and hyperfunction theory: reinterpreting the mechanisms of aging

in Aging and Cancer

Lev Salnikov

Frontiers in Aging

doi 10.3389/fragi.2026.1735269

1,207 views

671 articles

articles

Unwanted loneliness among older adults in rural areas: associated factors and guidelines for community intervention

Cardiovascular Risk Factor Changes Associated with Six-Year Circuit Training in Older Adults: A Retrospective Cohort Analysis

Promoting healthy aging in a digital world: leveraging technology for enhanced elderly care and wellbeing

Tensiomyography-derived contractile parameters in sarcopenic and non-sarcopenic older adults

Molecular pathways linking chronic psychological stress to accelerated aging: mechanisms and interventions

Gene–Gene and Gene–Environment Interactions among CYP19A1, ESR1, IL6, IL6R, IL1β, RANK and RANKL variants associated with Osteoporosis and Hip Fracture in Mexican Women

Obesity and Low Lean Mass Are Associated with Dysregulated IGFBP-3, Inflammatory Biomarkers, and Physical Impairment in Older Adult Women with Frailty

Phenotypic and functional heterogeneity of naïve CD8+ T cells in human peripheral blood during aging

Intravenous infusion of nicotinamide adenine dinucleotide (NAD+) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting

Research hotspots and trends of senolytic therapy: a bibliometric and visualization analysis from 2015 to 2025

PCKP versus UPKP for Moderate-to-Severe Osteoporotic Vertebral Compression Fractures: A Prospective Randomized Controlled Trial Revealing Synergistic Mechanisms of Optimized Bone Cement Distribution and Anti-Osteoporosis Therapy on Medium-to Long-Term Outcomes

Periorbital skin index as a biomarker for biological aging and health status

Combined spinal cord stimulation and intrathecal Morphine–Sufentanil therapy for refractory cancer pain: a case report

A comprehensive review of artificial intelligence as a catalyst in aging research: insights, gaps and future perspectives

Impact of Comorbidities in Patients with Erosive Hand Osteoarthritis (EHOA), a monocentric study

Does Time Spent Upright Moderate the Influence of a Weighted Vest on Change in Bone Mineral Density During Weight Loss among Older Adults? A Secondary Analysis of the INVEST in Bone Health Randomized Controlled Trial

Effect of milk and dairy intake on cognitive function in older adults: a systematic review and meta-analysis

Non-pharmacological mental health interventions for older adults in México: A systematic review

The Tight Bond Between Fanconi Anemia and Aging

Editorial: Insights in Genetics, Genomics and Epigenomics of Aging:2025

Time to stand up faster: underutilization of real-world sit-to-stand transition velocity in aging research

Within- and between-individual associations between sleep and cognition in older community-dwelling individuals

One-month Early Time-Restricted Eating Mitigates Brain Aging and Enhances Memory in Males with Metabolic Syndrome: An MRI Structural Study

Epigenetic program of ontogenesis and hyperfunction theory: reinterpreting the mechanisms of aging