Frontiers in Aging

Original Research

Published on 22 Apr 2025

A comparative analysis of binary and multi-class classification machine learning algorithms to detect current frailty status using the English longitudinal study of ageing (ELSA)

in Musculoskeletal Aging

Charmayne Mary Lee Hughes
Yan Zhang
Ali Pourhossein
Terezia Jurasova

Frontiers in Aging

doi 10.3389/fragi.2025.1501168

4,227 views
2 citations

Original Research

Published on 16 Apr 2025

Multivariate analysis of immunosenescence data in healthy humans and diverse diseases

in Healthy Longevity

Ana Laura Añé-Kourí
Jorge Luis Palomino
Patricia Lorenzo-Luaces
Lizet Sanchez
Nuris Ledon
Karla Pereira
Jenysbel de la Caridad Hernandez
Gisela María Suárez
Beatriz García
Amnely González

Frontiers in Aging

doi 10.3389/fragi.2025.1568034

7,137 views

Original Research

Published on 16 Apr 2025

Analysis of the senescence secretome during zebrafish retina regeneration

in Cellular Senescence

Gregory J. Konar
Kyle T. Vallone
Tu D. Nguyen
James G. Patton

Frontiers in Aging

doi 10.3389/fragi.2025.1569422

3,392 views
1 citation

Systematic Review

Published on 11 Apr 2025

A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise

in Interventions in Aging

Ethan C. J. Berry
Nicholas F. Sculthorpe
Ashley Warner
James D. Mather
Nilihan E. M. Sanal-Hayes
Lawrence D. Hayes

Frontiers in Aging

doi 10.3389/fragi.2025.1516481

6,087 views
8 citations

Systematic Review

Published on 10 Apr 2025

Global research trends in inflammaging from 2005 to 2024: a bibliometric analysis

in Aging and the Immune System

Beier Jiang
Yi-ni Dong
Yu Xiong
Chun-xia Jiang
Jun Ping
Qi Wu
Liu-jun Xu
Run-zhe Shu
Dan-dan Gao
Sheng-mei Zhu

Frontiers in Aging

doi 10.3389/fragi.2025.1554186

7,530 views
5 citations

Review

Published on 07 Apr 2025

Age-defying swallowing

in Healthy Longevity

María-Itatí Palacio
Rosa-María Bermejo
Ana-María Lucas-Ochoa
Ana-María González-Cuello
Emiliano Fernández-Villalba
María-Trinidad Herrero

Frontiers in Aging

doi 10.3389/fragi.2025.1510257

11,156 views
1 citation

Review

Published on 07 Apr 2025

Growth hormone and aging: a clinical review

in Molecular Mechanisms of Aging

Luis E. Fernández-Garza
Fernando Guillen-Silva
Marcos A. Sotelo-Ibarra
Andrés Ely Domínguez-Mendoza
Silvia A. Barrera-Barrera
Hugo A. Barrera-Saldaña

Frontiers in Aging

doi 10.3389/fragi.2025.1549453

18,610 views
7 citations

Editorial

Published on 02 Apr 2025

Editorial: Aging and neurodegeneration in the brain

in Molecular Mechanisms of Aging

F. Kerr
K. J. Kinghorn
T. Niccoli
N. Woodling

Frontiers in Aging

doi 10.3389/fragi.2025.1581161

1,850 views

Original Research

Published on 31 Mar 2025

Dietary intake in healthy older individuals is associated with lipopolysaccharide binding protein a biomarker of gut function: an exploratory cross-sectional study

in Healthy Longevity

Debra Jones
Douglas J. Morrison
Stuart R. Gray
Susan E. Ozanne
Carlos Celis-Morales
Mahek Jain
Lewis R. Mattin
Matthew Gittins
Saleh A. A. Alkhedhairi
James L. Dorling

Frontiers in Aging

doi 10.3389/fragi.2025.1572867

8,406 views
1 citation

Review

Published on 31 Mar 2025

Premature aging and metabolic diseases: the impact of telomere attrition

in Aging and the Immune System

Sandhya Jinesh
Burçin Özüpek
Prerana Aditi

Frontiers in Aging

doi 10.3389/fragi.2025.1541127

7,862 views
11 citations

Original Research

Published on 28 Mar 2025

Human dermal fibroblast senescence in response to single and recurring oxidative stress

in Cellular Senescence

Tailynn Y. McCarty
Cathal J. Kearney

Frontiers in Aging

doi 10.3389/fragi.2025.1504977

7,365 views
5 citations

Original Research

Published on 25 Mar 2025

Relationship between preoperative high arterial blood lactate level and delirium after deep brain stimulation surgery in Parkinson’s disease

in Aging, Metabolism and Redox Biology

Wenbin Lu
Miaomiao Rao
Liangliang Lu
Panpan Li
Xiaorong Dou
Jinjun Bian
Xiaoming Deng

Frontiers in Aging

doi 10.3389/fragi.2025.1538012

2,024 views

Original Research

Published on 24 Mar 2025

The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study

in Musculoskeletal Aging

Rong Tian
Osvaldo P. Almeida
Andrew H. Ford
Leon Flicker
Nicola T. Lautenschlager
Suzanne Robinson
Marshall Makate
Simone Pettigrew
Sin Huey Lee
Ina Dorsheimer

Frontiers in Aging

doi 10.3389/fragi.2025.1524186

2,966 views

Original Research

Published on 21 Mar 2025

Yoga an integrated mind body intervention for improvement in quality of life in individuals with Alzheimer’s disease and their caregivers

in Interventions in Aging

Meenakshi Kaushik
Anjali Yadav
Ashishdatt Upadhyay
Anu Gupta
Prabhakar Tiwari
Manjari Tripathi
Rima Dada

Frontiers in Aging

doi 10.3389/fragi.2025.1449485

7,051 views
9 citations

Review

Published on 20 Mar 2025

Rock inhibitors in Alzheimer’s disease

in Aging, Metabolism and Redox Biology

Chao Zheng
Weiming Xia
Jianhua Zhang

Frontiers in Aging

doi 10.3389/fragi.2025.1547883

5,290 views
2 citations

Systematic Review

Published on 19 Mar 2025

The influence of circulating cholesterol and its components in middle-aged adults on cognitive function at mid- and later-life; a systematic review

in Interventions in Aging

O. C. Joyce
C. McHugh
D. Mockler
F. Wilson
Á. M. Kelly

Frontiers in Aging

doi 10.3389/fragi.2025.1430382

2,901 views

Original Research

Published on 19 Mar 2025

60 is the new 40: preparing for better bone health in later life

in Healthy Longevity

Leo Westbury
Kamran Gaba
Gregorio Bevilacqua
Nicholas Fuggle
Elaine Dennison

Frontiers in Aging

doi 10.3389/fragi.2025.1490124

9,870 views

Original Research

Published on 10 Mar 2025

Association of systemic immune-inflammatory index with all-cause and cancer mortality in Americans aged 60 years and older

in Aging and the Immune System

Wangfeng Lu
Yuliang Gong
Lei Liu
Yonghong Zhang
Xiaojian Tian
Huanxian Liu

Frontiers in Aging

doi 10.3389/fragi.2025.1502746

3,044 views
2 citations

Original Research

Published on 28 Feb 2025

Multiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age

in Genetics, Genomics and Epigenomics of Aging

Bowen Zhu
Dean Li
Guojing Han
Xue Yao
Hongqin Gu
Tao Liu
Linghua Liu
Jie Dai
Isabella Zhaotong Liu
Yanlin Liang

Frontiers in Aging

doi 10.3389/fragi.2025.1467639

2,733 views
1 citation

Brief Research Report

Published on 27 Feb 2025

Comparison of characteristics of bimanual coordinated movements in older adults with frailty, pre-frailty, and robust health

in Healthy Longevity

Shoya Fujikawa
Shin Murata
Akio Goda
Shun Sawai
Ryosuke Yamamoto
Yusuke Shizuka
Takayuki Maru
Kotaro Nakagawa
Hideki Nakano

Frontiers in Aging

doi 10.3389/fragi.2025.1519129

9,104 views
3 citations

Original Research

Published on 26 Feb 2025

Demographic, health, and behaviors profile of Saudi Arabia’s aging population 2022–2023

in Healthy Longevity

Nasser F. Bindhim
Mohammed Senitan
Madhawi N. Almutairi
Leen S. Alhadlaq
Sundus A. Alnajem
Maryam Ali Alfaifi
Nora A. Althumiri

Frontiers in Aging

doi 10.3389/fragi.2025.1491146

15,146 views
4 citations

Original Research

Published on 13 Feb 2025

Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model

in Musculoskeletal Aging

Pablo Gallo-Soljancic
Maria Egle De Stefano
Ana-María Lucas-Ochoa
Consuelo Sánchez-Rodrigo
Lorena Cuenca-Bermejo
Ana-María González-Cuello
Emiliano Fernández-Villalba
María-Trinidad Herrero

Frontiers in Aging

doi 10.3389/fragi.2025.1486670

3,031 views
1 citation

Original Research

Published on 13 Feb 2025

Klotho protects INS-1 pancreatic β-cells from senescence and enhances mitochondrial function

in Cellular Senescence

Zhihong Wang
Yunzhi Ni
Yan-Ru Lou
Gerald J. Prud’homme
Qinghua Wang

Frontiers in Aging

doi 10.3389/fragi.2025.1512322

3,772 views
2 citations

Original Research

Published on 11 Feb 2025

Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study

in Healthy Longevity

Aiguo Liu
Ting Ying
Shuang Deng
Chenxu Wang
Ziwen Zhao
Sitong Zhang
Han Xiao
Chengqing Yi
Dejian Li

Frontiers in Aging

doi 10.3389/fragi.2025.1511294

10,879 views

676 articles

articles

A comparative analysis of binary and multi-class classification machine learning algorithms to detect current frailty status using the English longitudinal study of ageing (ELSA)

Multivariate analysis of immunosenescence data in healthy humans and diverse diseases

Analysis of the senescence secretome during zebrafish retina regeneration

A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise

Global research trends in inflammaging from 2005 to 2024: a bibliometric analysis

Age-defying swallowing

Growth hormone and aging: a clinical review

Editorial: Aging and neurodegeneration in the brain

Dietary intake in healthy older individuals is associated with lipopolysaccharide binding protein a biomarker of gut function: an exploratory cross-sectional study

Premature aging and metabolic diseases: the impact of telomere attrition

Human dermal fibroblast senescence in response to single and recurring oxidative stress

Relationship between preoperative high arterial blood lactate level and delirium after deep brain stimulation surgery in Parkinson’s disease

The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study

Yoga an integrated mind body intervention for improvement in quality of life in individuals with Alzheimer’s disease and their caregivers

Rock inhibitors in Alzheimer’s disease

The influence of circulating cholesterol and its components in middle-aged adults on cognitive function at mid- and later-life; a systematic review

60 is the new 40: preparing for better bone health in later life

Association of systemic immune-inflammatory index with all-cause and cancer mortality in Americans aged 60 years and older

Multiplexing and massive parallel sequencing of targeted DNA methylation to predict chronological age

Comparison of characteristics of bimanual coordinated movements in older adults with frailty, pre-frailty, and robust health

Demographic, health, and behaviors profile of Saudi Arabia’s aging population 2022–2023

Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model

Klotho protects INS-1 pancreatic β-cells from senescence and enhances mitochondrial function

Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study