Frontiers in Aging

Original Research

Published on 27 Sep 2021

Evidence that C/EBP-β LAP Increases Fat Metabolism and Protects Against Diet-Induced Obesity in Response to mTOR Inhibition

in Interventions in Aging

Alessandro Bitto
Nicole Tatom
Thomas Krivak
Peter Grotz
Matt Kaeberlein

Frontiers in Aging

doi 10.3389/fragi.2021.738512

5,829 views
13 citations

Review

Published on 24 Sep 2021

Estrogen Receptor and Vascular Aging

in Molecular Mechanisms of Aging

Morgane Davezac
Melissa Buscato
Rana Zahreddine
Patrick Lacolley
Daniel Henrion
Francoise Lenfant
Jean-Francois Arnal
Coralie Fontaine

Frontiers in Aging

doi 10.3389/fragi.2021.727380

12,189 views
47 citations

Mini Review

Published on 23 Sep 2021

Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

in Interventions in Aging

Priya Balasubramanian
Jordan Delfavero
Adam Nyul-Toth
Amber Tarantini
Rafal Gulej
Stefano Tarantini

Frontiers in Aging

doi 10.3389/fragi.2021.678543

14,922 views
14 citations

Review

Published on 22 Sep 2021

Implications of Inflammatory States on Dysfunctional Immune Responses in Aging and Obesity

in Aging and the Immune System

Alyssa L. Thomas
Pablo C. Alarcon
Senad Divanovic
Claire A. Chougnet
David A. Hildeman
Maria E. Moreno-Fernandez

Frontiers in Aging

doi 10.3389/fragi.2021.732414

7,162 views
32 citations

Review

Published on 10 Sep 2021

Sex Differences in Molecular Mechanisms of Cardiovascular Aging

in Molecular Mechanisms of Aging

Vanessa Dela Justina
Jéssica S. G. Miguez
Fernanda Priviero
Jennifer C. Sullivan
Fernanda R. Giachini
R. Clinton Webb

Frontiers in Aging

doi 10.3389/fragi.2021.725884

10,955 views
40 citations

Original Research

Published on 10 Sep 2021

Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

in Interventions in Aging

Amber C. Howard
Dilawar Mir
Santina Snow
Jordan Horrocks
Hussein Sayed
Zhengxin Ma
Aric N. Rogers

Frontiers in Aging

doi 10.3389/fragi.2021.725068

5,675 views
12 citations

Review

Published on 08 Sep 2021

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence

in Molecular Mechanisms of Aging

Paula R. Barros
Tiago J. Costa
Eliana H. Akamine
Rita C. Tostes

Frontiers in Aging

doi 10.3389/fragi.2021.727604

14,543 views
23 citations

Mini Review

Published on 08 Sep 2021

Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

in Interventions in Aging

Collin Y. Ewald

Frontiers in Aging

doi 10.3389/fragi.2021.741843

23,362 views
22 citations

Review

Published on 31 Aug 2021

ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function

in Molecular Mechanisms of Aging

Andrew V. Kuczmarski
Laura M. Welti
Kerrie L. Moreau
Megan M. Wenner

Frontiers in Aging

doi 10.3389/fragi.2021.727416

6,902 views
23 citations

Review

Published on 31 Aug 2021

In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease

in Interventions in Aging

Martin Borch Jensen
Adam Marblestone

Frontiers in Aging

doi 10.3389/fragi.2021.714926

22,435 views
6 citations

Review

Published on 27 Aug 2021

The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging

in Interventions in Aging

Stephanie A. Fernandes
Constantinos Demetriades

Frontiers in Aging

doi 10.3389/fragi.2021.707372

23,942 views
98 citations

Mini Review

Published on 26 Aug 2021

Aging: What We Can Learn From Elephants

in Aging, Metabolism and Redox Biology

Daniella E. Chusyd
Nicole L. Ackermans
Steven N. Austad
Patrick R. Hof
Michelle M. Mielke
Chet C. Sherwood
David B. Allison

Frontiers in Aging

doi 10.3389/fragi.2021.726714

17,712 views
19 citations

Original Research

Published on 20 Aug 2021

Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

in Aging and the Immune System

Stephen N. Crooke
Krista M. Goergen
Inna G. Ovsyannikova
Richard B. Kennedy

Frontiers in Aging

doi 10.3389/fragi.2021.719103

4,144 views
3 citations

Original Research

Published on 13 Aug 2021

Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8+ EMRA T Cells During Type 2 Diabetes

in Aging and the Immune System

Lauren A. Callender
Elizabeth C. Carroll
Conor Garrod-Ketchley
Johannes Schroth
Jonas Bystrom
Victoria Berryman
Melanie Pattrick
Desiree Campbell-Richards
Gillian A. Hood
Graham A. Hitman

Frontiers in Aging

doi 10.3389/fragi.2021.681428

6,693 views
22 citations

Mini Review

Published on 11 Aug 2021

Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA

in Molecular Mechanisms of Aging

Kaoru Sato
Ken-ichi Takayama
Makoto Hashimoto
Satoshi Inoue

Frontiers in Aging

doi 10.3389/fragi.2021.721579

8,663 views
20 citations

Original Research

Published on 10 Aug 2021

Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals

in Aging and the Immune System

Norihide Jo
Rui Zhang
Hideki Ueno
Takuya Yamamoto
Daniela Weiskopf
Miki Nagao
Shinya Yamanaka
Yoko Hamazaki

Frontiers in Aging

doi 10.3389/fragi.2021.719342

10,682 views
23 citations

Original Research

Published on 09 Aug 2021

Curiosity-Based Interventions Increase Everyday Functioning Score But Not Serum BDNF Levels in a Cohort of Healthy Older Adults

in Interventions in Aging

Allison N. Grossberg
Brianne M. Bettcher
Kim A. Gorgens
Aurélie Ledreux

Frontiers in Aging

doi 10.3389/fragi.2021.700838

4,174 views
1 citation

Brief Research Report

Published on 29 Jul 2021

Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

in Genetics, Genomics and Epigenomics of Aging

Fedor Galkin
Kirill Kochetov
Polina Mamoshina
Alex Zhavoronkov

Frontiers in Aging

doi 10.3389/fragi.2021.697254

8,589 views
8 citations

Original Research

Published on 27 Jul 2021

Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

in Molecular Mechanisms of Aging

Jianjie Wang
Murtaza M. Kazmi
Virginia H. Huxley

Frontiers in Aging

doi 10.3389/fragi.2021.719698

4,486 views
6 citations

Systematic Review

Published on 23 Jul 2021

Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19

in Aging and the Immune System

Alan Landay
Jenna M. Bartley
Dishary Banerjee
Geneva Hargis
Laura Haynes
Ali Keshavarzian
Chia-Ling Kuo
Oh Sung Kwon
Sheng Li
Shuzhao Li

Frontiers in Aging

doi 10.3389/fragi.2021.695218

9,795 views
5 citations

Original Research

Published on 23 Jul 2021

Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus

in Aging and the Immune System

Daniela Frasca
Alain Diaz
Maria Romero
Bonnie B. Blomberg

Frontiers in Aging

doi 10.3389/fragi.2021.715981

7,874 views
33 citations

Review

Published on 19 Jul 2021

Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification

in Aging and the Immune System

Petra Lázničková
Kamila Bendíčková
Tomáš Kepák
Jan Frič

Frontiers in Aging

doi 10.3389/fragi.2021.708788

6,214 views
8 citations

Review

Published on 16 Jul 2021

Stem Cells in the Myelodysplastic Syndromes

in Aging and Cancer

Di Zhan
Christopher Y. Park

Frontiers in Aging

doi 10.3389/fragi.2021.719010

9,742 views
8 citations

Brief Research Report

Published on 15 Jul 2021

Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging

in Interventions in Aging

Rebecca L. McIntyre
Mizanur Rahman
Siva A. Vanapalli
Riekelt H. Houtkooper
Georges E. Janssens

Frontiers in Aging

doi 10.3389/fragi.2021.708680

15,606 views
18 citations

677 articles

articles

Evidence that C/EBP-β LAP Increases Fat Metabolism and Protects Against Diet-Induced Obesity in Response to mTOR Inhibition

Estrogen Receptor and Vascular Aging

Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia

Implications of Inflammatory States on Dysfunctional Immune Responses in Aging and Obesity

Sex Differences in Molecular Mechanisms of Cardiovascular Aging

Anabolic Function Downstream of TOR Controls Trade-offs Between Longevity and Reproduction at the Level of Specific Tissues in C. elegans

Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence

Drug Screening Implicates Chondroitin Sulfate as a Potential Longevity Pill

ET-1 as a Sex-Specific Mechanism Impacting Age-Related Changes in Vascular Function

In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related Disease

The Multifaceted Role of Nutrient Sensing and mTORC1 Signaling in Physiology and Aging

Aging: What We Can Learn From Elephants

Inflammasome Activity in Response to Influenza Vaccination Is Maintained in Monocyte-Derived Peripheral Blood Macrophages in Older Adults

Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8+ EMRA T Cells During Type 2 Diabetes

Transcriptional and Post-Transcriptional Regulations of Amyloid-β Precursor Protein (APP) mRNA

Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals

Curiosity-Based Interventions Increase Everyday Functioning Score But Not Serum BDNF Levels in a Cohort of Healthy Older Adults

Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

Microvascular Sex- and Age- Dependent Phosphodiesterase Expression

Network Topology of Biological Aging and Geroscience-Guided Approaches to COVID-19

Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus

Immunosenescence in Childhood Cancer Survivors and in Elderly: A Comparison and Implication for Risk Stratification

Stem Cells in the Myelodysplastic Syndromes

Biological Age Prediction From Wearable Device Movement Data Identifies Nutritional and Pharmacological Interventions for Healthy Aging