volumes

Volume 3 - 2022

Original Research

Published on 07 Mar 2022

A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage

Giulia Lizzo
Eugenia Migliavacca
Daniela Lamers
Adrien Frézal
John Corthesy
Gerard Vinyes-Parès
Nabil Bosco
Leonidas G. Karagounis
Ulrike Hövelmann
Tim Heise

Frontiers in Aging

doi 10.3389/fragi.2022.852569

100,005 views
16 citations

Review

Published on 03 Mar 2022

Role of BAG5 in Protein Quality Control: Double-Edged Sword?

Manish K. Gupta
Puneet Kaur Randhawa
Michal M. Masternak

Frontiers in Aging

doi 10.3389/fragi.2022.844168

5,711 views
7 citations

Brief Research Report

Published on 21 Feb 2022

Differential Effects of 2-Deoxyglucose and Glucose Deprivation on 4-Hydroxynonenal Dependent Mitochondrial Dysfunction in Primary Neurons

Matthew Dodson
Gloria A. Benavides
Victor Darley-Usmar
Jianhua Zhang

Frontiers in Aging

doi 10.3389/fragi.2022.812810

4,316 views
5 citations

Mini Review

Published on 15 Feb 2022

Age and Sex Differences in Heart Failure With Preserved Ejection Fraction

Kamil Aleksander Kobak
Weronika Zarzycka
Ying Ann Chiao

Frontiers in Aging

doi 10.3389/fragi.2022.811436

9,571 views
14 citations

Original Research

Published on 14 Feb 2022

Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging

Lea Hänschke
Christoph Heier
Santiago José Maya Palacios
Huseyin Erdem Özek
Christoph Thiele
Reinhard Bauer
Ronald P. Kühnlein
Margret H. Bülow

Frontiers in Aging

doi 10.3389/fragi.2022.800153

6,729 views
15 citations

Mini Review

Published on 11 Feb 2022

Roadmap for Sex-Responsive Influenza and COVID-19 Vaccine Research in Older Adults

Janna R. Shapiro
Rosemary Morgan
Sean X. Leng
Sabra L. Klein

Frontiers in Aging

doi 10.3389/fragi.2022.836642

6,460 views
12 citations

Mini Review

Published on 09 Feb 2022

Growth Differentiation Factor-15 in Immunity and Aging

Brandt D. Pence

Frontiers in Aging

doi 10.3389/fragi.2022.837575

9,974 views
60 citations

Mini Review

Published on 04 Feb 2022

Clinical Trials Targeting Aging

Johannes Leth Nielsen
Daniela Bakula
Morten Scheibye-Knudsen

Frontiers in Aging

doi 10.3389/fragi.2022.820215

60,569 views
49 citations

Perspective

Published on 02 Feb 2022

The Importance of Motivation to Older Adult Physical and Cognitive Exercise Program Development, Initiation, and Adherence

Therese M. O’Neil-Pirozzi
Gabriele Cattaneo
Javier Solana-Sánchez
Joyce Gomes-Osman
Alvaro Pascual-Leone

Frontiers in Aging

doi 10.3389/fragi.2022.773944

13,364 views
17 citations

Original Research

Published on 25 Jan 2022

Age-Associated Changes to Lymph Node Fibroblastic Reticular Cells

Tina Kwok
Shannon C. Medovich
Ildefonso A. Silva-Junior
Elise M. Brown
Joel C. Haug
Marliece R. Barrios
Karina A. Morris
Jessica N. Lancaster

Frontiers in Aging

doi 10.3389/fragi.2022.838943

12,109 views
32 citations

Mini Review

Published on 19 Jan 2022

The Impact of Aging on the Lung Alveolar Environment, Predetermining Susceptibility to Respiratory Infections

Jordi B. Torrelles
Blanca I. Restrepo
Yidong Bai
Corinna Ross
Larry S. Schlesinger
Joanne Turner

Frontiers in Aging

doi 10.3389/fragi.2022.818700

12,287 views
22 citations

Volume 2 - 2021

Review

Published on 03 Mar 2022

Implications of Sphingolipids on Aging and Age-Related Diseases

Shengxin Li
Hyun-Eui Kim

Frontiers in Aging

doi 10.3389/fragi.2021.797320

11,641 views
31 citations

Original Research

Published on 03 Feb 2022

Direct Imaging of Lipid Metabolic Changes in Drosophila Ovary During Aging Using DO-SRS Microscopy

Yajuan Li
Pegah Bagheri
Phyllis Chang
Audrey Zeng
Jie Hao
Anthony Fung
Jane Y. Wu
Lingyan Shi

Frontiers in Aging

doi 10.3389/fragi.2021.819903

7,329 views
35 citations

Original Research

Published on 03 Feb 2022

Gene Expression Analysis Reveals Age and Ethnicity Signatures Between Young and Old Adults in Human PBMC

Yang Hu
Yudai Xu
Lipeng Mao
Wen Lei
Jian Xiang
Lijuan Gao
Junxing Jiang
Li`an Huang
Oscar Junhong Luo
Jinhai Duan

Frontiers in Aging

doi 10.3389/fragi.2021.797040

10,674 views
17 citations

Original Research

Published on 02 Feb 2022

Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice

Ke Yun Chen
Alejandra De Angulo
Xin Guo
Aditya More
Scott A. Ochsner
Eduardo Lopez
David Saul
Weijun Pang
Yuxiang Sun
Neil J. McKenna

Frontiers in Aging

doi 10.3389/fragi.2021.803482

6,514 views
10 citations

Original Research

Published on 02 Feb 2022

Reduced Bordetella pertussis-specific CD4+ T-Cell Responses at Older Age

Eleonora E. Lambert
Inonge van Twillert
Lisa Beckers
Martien C. M. Poelen
Wanda G. H. Han
Daan K. J. Pieren
Cécile A. C. M. van Els

Frontiers in Aging

doi 10.3389/fragi.2021.737870

5,705 views
8 citations

Original Research

Published on 26 Jan 2022

Removal of p16INK4 Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice

Steve D. Guzman
Jennifer Judge
Shahjahan M. Shigdar
Thomas A. Paul
Carol S. Davis
Peter C. Macpherson
James F. Markworth
Holly Van Remmen
Arlan Richardson
Anne McArdle

Frontiers in Aging

doi 10.3389/fragi.2021.821904

8,126 views
11 citations

Review

Published on 20 Jan 2022

Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases

Tugce Demirel-Yalciner
Erdi Sozen
Nesrin Kartal Ozer

Frontiers in Aging

doi 10.3389/fragi.2021.790702

8,546 views
12 citations

Original Research

Published on 13 Jan 2022

Obesity Accelerates Age-Associated Defects in Human B Cells Through a Metabolic Reprogramming Induced by the Fatty Acid Palmitate

Daniela Frasca
Maria Romero
Denisse Garcia
Alain Diaz
Bonnie B. Blomberg

Frontiers in Aging

doi 10.3389/fragi.2021.828697

5,676 views
27 citations

Original Research

Published on 12 Jan 2022

G-quadruplexes Stabilization Upregulates CCN1 and Accelerates Aging in Cultured Cerebral Endothelial Cells

Brian Noh
Maria P. Blasco-Conesa
Yun-Ju Lai
Bhanu Priya Ganesh
Akihiko Urayama
Ines Moreno-Gonzalez
Sean P. Marrelli
Louise D. McCullough
Jose Felix Moruno-Manchon

Frontiers in Aging

doi 10.3389/fragi.2021.797562

7,396 views
13 citations

Review

Published on 10 Jan 2022

The Complicated Nature of Somatic mtDNA Mutations in Aging

Monica Sanchez-Contreras
Scott R. Kennedy

Frontiers in Aging

doi 10.3389/fragi.2021.805126

11,884 views
51 citations

Systematic Review

Published on 03 Jan 2022

Effects of Hyperoxia on Aging Biomarkers: A Systematic Review

Belay Tessema
Ulrich Sack
Zoya Serebrovska
Brigitte König
Egor Egorov

Frontiers in Aging

doi 10.3389/fragi.2021.783144

14,400 views
4 citations

Original Research

Published on 03 Jan 2022

Prescription Medications and Co-Morbidities in Late Middle-Age are Associated with Greater Cognitive Declines: Results from WRAP

Lianlian Du
Rebecca Langhough Koscik
Nathaniel A. Chin
Lisa C. Bratzke
Karly Cody
Claire M. Erickson
Erin Jonaitis
Kimberly D. Mueller
Bruce P. Hermann
Sterling C. Johnson

Frontiers in Aging

doi 10.3389/fragi.2021.759695

4,655 views
10 citations

Mini Review

Published on 03 Jan 2022

Identification of Somatic Mutations From Bulk and Single-Cell Sequencing Data

August Yue Huang
Eunjung Alice Lee

Frontiers in Aging

doi 10.3389/fragi.2021.800380

16,878 views
17 citations