POLICY AND PRACTICE REVIEWS article

Front. Artif. Intell.

Sec. Medicine and Public Health

Volume 8 - 2025 | doi: 10.3389/frai.2025.1496937

Population Health Management Human Phenotype Ontology Policy for Ecosystem Improvement

Provisionally accepted
  • Institute of biomedical sciences, London, United Kingdom

The final, formatted version of the article will be published soon.

ABSTRACTAim The manuscript "Population Health Management (PHM) Human Phenotype Ontology (HPO) Policy for Ecosystem Improvement" steward safe science and secure technology in medical reform. The digital HPO policy advances Biological Modelling (BM) capacity and capability in a series for fair classifications. Public trust in the PHM of HPO, is a vision of public health and patient safety, with a primary goal of socioeconomic success sustained by citizen privacy and trust within an ecosystem of predictor equality and intercept parity.Method Science and technology security evaluation, resource allocation, and appropriate regulation are essential for establishing a solid foundation in a safe ecosystem. The AI Security Institute collaborates with higher experts to assess BM cybersecurity and privacy. Within this ecosystem, AI resource metrics as genomic medical sciences cluster and assess safe HPO transformations. These efforts ensure that AI digital regulation acts as a service appropriate to steward progressive PHM.Recommendations The manuscript presents a five-point mission for the effective management of population health. A comprehensive national policy for phenotype ontology with Higher Expert Medical Science Safety stewards reform across sectors. It emphasises developing genomic predictors and intercepts, authorising predictive health pre-exams and precise care eXams, adopting Generative AI classifications, and expanding the PHM ecosystem in benchmark reforms.Discussion Discussions explore medical reform focusing on public health and patient safety. The nation's safe space expansions with continual improvements include steward developing, authorising, and adopting digital BM twins. The manuscript addresses international classifications where the global development of PHM enables nations to choose what to authorise for BM points of need. These efforts promote channels for adopting HPO uniformity, transforming research findings into routine phenotypical primary care practices.Conclusion This manuscript charts the UK's and global PHM's ecosystem expansion, designing HPO policies that steward the modelling of biology in personal classifications. It develops secure, safe, fair, and explainable BM for public trust in authorised classifiers and promotes informed choices regarding what nations and individuals adopt in a cooperative PHM progression. Championing equitable classifications in a robust ecosystem sustains advancements in population health outcomes for economic growth and public health betterment.

Keywords: Population health management, Safety, security, Predictive health, Precision Care, Classifications, Human Phenotype Ontology Policy

Received: 15 Sep 2024; Accepted: 16 May 2025.

Copyright: © 2025 Henry. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: James Andrew Henry, Institute of biomedical sciences, London, United Kingdom

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.