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ORIGINAL RESEARCH article

Front. Artif. Intell.

Sec. Medicine and Public Health

Volume 8 - 2025 | doi: 10.3389/frai.2025.1639720

This article is part of the Research TopicComputational Intelligence for Multimodal Biomedical Data FusionView all articles

Artificial Liver Classifier: A New Alternative to Conventional Machine Learning Models

Provisionally accepted
Mahmood  A JumaahMahmood A Jumaah1*Yossra  H AliYossra H Ali1*Tarik  A. RashidTarik A. Rashid2,3*
  • 1University of Technology, Baghdad, Baghdad, Iraq
  • 2University of Kurdistan Hewler, Erbil, Iraq
  • 3University of Kurdistan Hewler Department of Computer Science, Erbil, Iraq

The final, formatted version of the article will be published soon.

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human liver's detoxification function. The ALC is characterized by its simplicity, speed, capability to reduce overfitting, and effectiveness in addressing multi-class classification problems through straightforward mathematical operations. To optimize the ALC's parameters, an improved FOX optimization algorithm (IFOX) is employed during training. We evaluate the proposed ALC on five benchmark datasets: Iris Flower, Breast Cancer Wisconsin, Wine, Voice Gender, and MNIST. The results demonstrate competitive performance, with ALC achieving up to 100% accuracy on the Iris dataset-surpassing logistic regression, multilayer perceptron, and support vector machine-and 99.12% accuracy on the Breast Cancer dataset, outperforming XGBoost and logistic regression. Across all datasets, ALC consistently shows smaller generalization gaps and lower loss values compared to conventional classifiers. These findings highlight the potential of biologically inspired models to develop efficient machine learning classifiers and open new avenues for innovation in the field.

Keywords: Artificial Liver Classifier, ALC, artificial intelligence, Classification, Intelligent systems, machine learning, optimization

Received: 02 Jun 2025; Accepted: 16 Jul 2025.

Copyright: © 2025 Jumaah, Ali and Rashid. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Mahmood A Jumaah, University of Technology, Baghdad, Baghdad, Iraq
Yossra H Ali, University of Technology, Baghdad, Baghdad, Iraq
Tarik A. Rashid, University of Kurdistan Hewler, Erbil, Iraq

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