Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Artif. Intell.

Sec. Medicine and Public Health

Volume 8 - 2025 | doi: 10.3389/frai.2025.1689182

This article is part of the Research TopicAI with Insight: Explainable Approaches to Mental Health Screening and Diagnostic Tools in HealthcareView all 8 articles

Machine Learning-Based Detection of Cognitive Decline Using SSWTRT: Classification Performance and Decision Analysis

Provisionally accepted
  • 1The University of Electro-Communications, Chofu, Japan
  • 2Juntendo University School of Medicine, Tokyo, Japan

The final, formatted version of the article will be published soon.

In high-income countries, early detection of dementia is a pressing public health priority. The Mini-Mental State Examination (MMSE) is the most widely used screening tool, but its administration requires trained personnel, limiting large-scale, cost-effective deployment. Building on prior findings that patients with dementia are prone to tactile perceptual impairments, we previously proposed the Sound-Symbolic Word Texture Recognition Test (SSWTRT) as a low-cost, low-resource method for the early detection of cognitive decline. Because SSWTRT has minimal time and resource demands, it may offer practical value when used to predict MMSE-defined risk groups. In this study, we applied machine-learning models to experimental SSWTRT data to classify individuals with suspected cognitive decline, such as those with possible MCI (e.g., MMSE ≤27), and evaluated model performance and outputs. We further analyzed model interpretability using SHapley Additive exPlanations (SHAP) to quantify each image's contribution to classification. The model achieved an accuracy of 0.71, precision of 0.72, recall of 0.72, and F1-score of 0.72, demonstrating potential utility for screening cognitive decline. SHAP analyses indicated that responses to specific images— particularly those depicting soft and coarse textures—had strong influence on predictions, suggesting an association between texture perception and cognitive decline.

Keywords: Sound symbolic words, Texture recognition, dementia4, Neuropsychological Tests, machine learning, Shap

Received: 20 Aug 2025; Accepted: 09 Oct 2025.

Copyright: © 2025 Nozaki, Kamohara, Abe, Ieda, Nakajima and Sakamoto. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Yuji Nozaki, na003169@uec.ac.jp
Maki Sakamoto, maki.sakamoto@uec.ac.jp

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.