EDITORIAL article
Front. Bioinform.
Sec. Genomic Analysis
Volume 5 - 2025 | doi: 10.3389/fbinf.2025.1641083
This article is part of the Research TopicExpert Opinions in Genomic AnalysisView all 5 articles
Editorial: Expert Opinions in Genomic Analysis
Provisionally accepted
- 1Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP, Brazil
- 2Fundacao Getulio Vargas, Rio de Janeiro, Brazil
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The issue is wrapped up with two papers on Standards in Genomics, a topic that is becoming increasingly important, as the number of genomic and metagenomic datasets continues to increase. The first, by Keenum et al. , addresses the issues of genomic data reuse and reproducibility. The authors provide convincing arguments that common metadata reporting, clear communication, standardized protocols, improved data management infrastructure, ethical guidelines, and collaborative policies that prioritize transparency and accessibility are the keys to enable the scientific community to address the double challenge of reproducibility and data reuse.The second paper, by Kelliher et al. , is a perspective piece that nicely follows up the previous one on the more specific theme of microbiome data reuse. Using results of a survey of more than 700 microbiome researchers, the authors have identified lack of standards in metadata records, challenges with bioinformatics, and problems with data repository submissions as the main reasons that make microbiome data sharing and reuse more difficult than they should be. The authors offer recommendations on how to overcome these challenges.In sum, we believe this collection to be a nice contribution to a small sample of important and timely topics in genome analysis.
Keywords: Genomics, microbiome, Protein design, large language models (LLM), Standards, RNA structure prediction, Data reuse
Received: 04 Jun 2025; Accepted: 10 Jun 2025.
Copyright: © 2025 Setubal and Paccanaro. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Joao Carlos Setubal, Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, 05508-000, SP, Brazil
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