Frontiers in Digital Health | Personalized Medicine

Original Research

Published on 18 Feb 2026

An explainable ensemble machine learning model using baseline blood transcriptomics to predict Parkinson's disease motor progression

in Personalized Medicine

Yelda Fırat

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1774436

781 views

Original Research

Published on 17 Feb 2026

Guideline-based strategies to identify severe cytokine release syndrome in COVID-19 and cancer immunotherapy using large-scale electronic health records

in Personalized Medicine

Philippe A. Robert
Jonas Denck
Cao Tri Do
Elif Ozkirimli
Candice Jamois
Chiara Corso
Ken Wang
Christoph T. Berger

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1625889

486 views

Systematic Review

Published on 17 Feb 2026

Real-world walking speed as a digital biomarker and outcome measure for clinical trials—a systematic review, regulatory status and future directions

in Personalized Medicine

Margaux Poleur
Cyril Tychon
Stephen Gilbert
Martin Daumer
Laurent Servais

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1726549

422 views

Review

Published on 16 Feb 2026

Multi-scale digital twins for personalized medicine

in Personalized Medicine

Alexandre Vallée

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1753906

291 views

Systematic Review

Published on 16 Feb 2026

From usability to clinical impact: a systematic review of digital technologies for motor rehabilitation in multiple sclerosis

in Personalized Medicine

Gabriele Triolo
Daniela Ivaldi
Roberta Lombardo
Angelo Quartarone
Viviana Lo Buono

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1692875

239 views

Correction

Published on 30 Jan 2026

Correction: The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

in Personalized Medicine

Myles Joshua Toledo Tan
Daniel Andrew Lichlyter
Nicholle Mae Amor Tan Maravilla
Weston John Schrock
Frederic Ivan Leong Ting
Joanna Marie Choa-Go
Kishi Kobe Francisco
Mickael Cavanaugh Byers
Hezerul Abdul Karim
Nouar AlDahoul

Frontiers in Digital Health

doi 10.3389/fdgth.2026.1775230

414 views

Perspective

Published on 12 Jan 2026

Merging multimodal digital biomarkers into “Digital Neuro Fingerprints” for precision neurology in dementias: the promise of the right treatment for the right patient at the right time in the age of AI

in Personalized Medicine

Ioannis Tarnanas
Azizi Seixas
Martin Wyss
Panagiotis Vlamos
Arzu Çöltekin

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1727707

1,111 views

Review

Published on 18 Nov 2025

Digital twins in healthcare: a comprehensive review and future directions

in Personalized Medicine

Hamid Khoshfekr Rudsari
Becky Tseng
Hongxu Zhu
Lulu Song
Chunhui Gu
Abhishikta Roy
Ehsan Irajizad
Joseph Butner
James Long
Kim-Anh Do

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1633539

9,162 views
8 citations

Study Protocol

Published on 08 Oct 2025

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

in Personalized Medicine

Guro Kleve
Chiara Dalla Santa
Felicia Kristiansen
Marita Tegnander
Victoria Buch
Cecilie Steen Hagemann
Marianne Helgheim
Parasto Engene
Henri Pesonen
Maiken Kojen Kleveland

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1609678

5,209 views
1 citation

Review

Published on 07 Aug 2025

Digital twin for personalized medicine development

in Personalized Medicine

Saniya Y. Saratkar
Meher Langote
Praveen Kumar
Pradnyawant Gote
Induni Nayodhara Weerarathna
Gaurav V. Mishra

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583466

11,224 views
22 citations

Mini Review

Published on 10 Jul 2025

Next generation performance status: digital health technologies across the lung cancer continuum

in Personalized Medicine

Julia Scarpa
Iqram Hussain
Alex Cheng
Jonathan Villena-Vargas
Richard Boyer

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1558180

2,123 views
1 citation

Perspective

Published on 18 Jun 2025

Bridging clinic to home: domestic devices in dermatological diagnostics and treatments

in Personalized Medicine

Diala Haykal
Frederic Flament

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1595484

3,343 views
2 citations

Original Research

Published on 10 Jun 2025

Analysis of the level of polypharmacy in patients from an isolated rural area: effect of age, sex, and chronic diseases

in Personalized Medicine

Susana Abdala Kuri
Chaxiraxi Morales
Alexis M. Oliva
Adama Peña
Sandra Dévora

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1508505

1,893 views

Original Research

Published on 12 May 2025

Interpretable AI-driven multi-objective risk prediction in heart failure patients with thyroid dysfunction

in Personalized Medicine

Massimo Iacoviello
Vito Santamato
Alessandro Pagano
Agostino Marengo

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583399

3,264 views
9 citations

Review

Published on 01 May 2025

Application of artificial intelligence and machine learning in lung transplantation: a comprehensive review

in Personalized Medicine

Xiting Liu
Wenqian Chen
Wenwen Du
Pengmei Li
Xiaoxing Wang

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1583490

3,986 views
4 citations

Original Research

Published on 30 Apr 2025

The quest for blood pressure markers in photoplethysmography and its applications in digital health

in Personalized Medicine

Josep Sola
Andreu Arderiu
Tiago P. Almeida
Sibylle Fallet
Sasan Yazdani
Serj Haddad
David Perruchoud
Olivier Grossenbacher
Jay Shah

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1518322

6,073 views
3 citations

Original Research

Published on 30 Apr 2025

Comparison of the diagnostic concordance of tele-EMS and EMS physicians in the emergency medical service—a subanalysis of the TEMS-trial

in Personalized Medicine

Patrick P. Hess
Michael Czaplik
Johanna Hess
Hanna Schröder
Stefan K. Beckers
Andreas Follmann
Mark Pitsch
Marc Felzen

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1519619

2,549 views

Systematic Review

Published on 04 Mar 2025

Global research landscape on nanotechnology in acute lung injury: a bibliometric analysis

in Personalized Medicine

Jian Zhang
Shasha Jiang
Jipeng Jiang
Yang Liu

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1472753

4,650 views
1 citation

Original Research

Published on 18 Feb 2025

Assessing accuracy of BiliPredics algorithm in predicting individual bilirubin progression in neonates—results from a prospective multi-center study

in Personalized Medicine

Britta Steffens
Gilbert Koch
Corinna Engel
Axel R. Franz
Marc Pfister
Sven Wellmann

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1497165

2,081 views
2 citations

Opinion

Published on 06 Feb 2025

The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

in Personalized Medicine

Myles Joshua Toledo Tan
Daniel Andrew Lichlyter
Nicholle Mae Amor Tan Maravilla
Weston John Schrock
Frederic Ivan Leong Ting
Joanna Marie Choa-Go
Kishi Kobe Francisco
Mickael Cavanaugh Byers
Hezerul Abdul Karim
Nouar AlDahoul

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1535018

6,354 views
9 citations

Review

Published on 23 Dec 2024

Artificial intelligence in respiratory care

in Personalized Medicine

Manjush Karthika
Jithin K. Sreedharan
Madhuragauri Shevade
Chris Sara Mathew
Santosh Ray

Frontiers in Digital Health

doi 10.3389/fdgth.2024.1502434

15,630 views
9 citations

Original Research

Published on 01 Nov 2024

A novel, machine-learning model for prediction of short-term ASCVD risk over 90 and 365 days

in Personalized Medicine

Tomer Gazit
Hanan Mann
Shiri Gaber
Pavel Adamenko
Granit Pariente
Liron Volsky
Amir Dolev
Helena Lyson
Eyal Zimlichman
Jay A. Pandit

Frontiers in Digital Health

doi 10.3389/fdgth.2024.1485508

5,610 views
2 citations

Editorial

Published on 25 Sep 2023

Editorial: Digital therapeutics: using software to treat, manage, and prevent disease

in Personalized Medicine

Kirsten E. Smayda
Tim Campellone
Sabrina R. Taylor
Brian Harris
Terry D. Ellis
Louis N. Awad

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1261124

2,880 views

Editorial

Published on 20 Sep 2023

Editorial: Wearable and mobile data analysis methodologies for personalized medicine

in Personalized Medicine

Ivan Miguel Pires
Ciprian Dobre
Eftim Zdravevski
Nuno M. Garcia

Frontiers in Digital Health

doi 10.3389/fdgth.2023.1271659

2,073 views
1 citation

90 articles

articles

An explainable ensemble machine learning model using baseline blood transcriptomics to predict Parkinson's disease motor progression

Guideline-based strategies to identify severe cytokine release syndrome in COVID-19 and cancer immunotherapy using large-scale electronic health records

Real-world walking speed as a digital biomarker and outcome measure for clinical trials—a systematic review, regulatory status and future directions

Multi-scale digital twins for personalized medicine

From usability to clinical impact: a systematic review of digital technologies for motor rehabilitation in multiple sclerosis

Correction: The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

Merging multimodal digital biomarkers into “Digital Neuro Fingerprints” for precision neurology in dementias: the promise of the right treatment for the right patient at the right time in the age of AI

Digital twins in healthcare: a comprehensive review and future directions

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

Digital twin for personalized medicine development

Next generation performance status: digital health technologies across the lung cancer continuum

Bridging clinic to home: domestic devices in dermatological diagnostics and treatments

Analysis of the level of polypharmacy in patients from an isolated rural area: effect of age, sex, and chronic diseases

Interpretable AI-driven multi-objective risk prediction in heart failure patients with thyroid dysfunction

Application of artificial intelligence and machine learning in lung transplantation: a comprehensive review

The quest for blood pressure markers in photoplethysmography and its applications in digital health

Comparison of the diagnostic concordance of tele-EMS and EMS physicians in the emergency medical service—a subanalysis of the TEMS-trial

Global research landscape on nanotechnology in acute lung injury: a bibliometric analysis

Assessing accuracy of BiliPredics algorithm in predicting individual bilirubin progression in neonates—results from a prospective multi-center study

The data scientist as a mainstay of the tumor board: global implications and opportunities for the global south

Artificial intelligence in respiratory care

A novel, machine-learning model for prediction of short-term ASCVD risk over 90 and 365 days

Editorial: Digital therapeutics: using software to treat, manage, and prevent disease

Editorial: Wearable and mobile data analysis methodologies for personalized medicine