GENERAL COMMENTARY article

Front. Genet., 27 February 2013

Sec. Neurogenomics

Volume 4 - 2013 | https://doi.org/10.3389/fgene.2013.00023

Erratum: Single-neuron RNA-Seq: technical feasibility and reproducibility

  • SQ

    Shenfeng Qiu 1,2

  • SL

    Shujun Luo 3

  • OE

    Oleg Evgrafov 1

  • RL

    Robin Li 3

  • GP

    Gary P. Schroth 3

  • PL

    Pat Levitt 1,2

  • JA

    James A. Knowles 1,4*

  • KW

    Kai Wang 1,4*

  • 1. Zilkha Neurogenetic Institute, University of Southern California Los Angeles, CA, USA

  • 2. Department of Cell and Neurobiology, University of Southern California Los Angeles, CA, USA

  • 3. Illumina, Inc. Hayward, CA, USA

  • 4. Department of Psychiatry, University of Southern California Los Angeles, CA, USA

To the Editor:

In our manuscript entitled “Single-neuron RNA-Seq: technical feasibility and reproducibility,” published online on July 6th, 2012, we have made a few serious mistakes which need to be corrected:

We referenced several points and quoted statements from a recent study by Okaty et al., but we neither cited the paper nor placed quotation marks on the statements. The full citation should be “Okaty, B. W., Sugino, K., and Nelson, S. B. (2011). Cell type-specific transcriptomics in the brain. J. Neurosci. 31, 6939–6943.”

We request to add a citation after “The analysis of each single-cell transcriptome consists of several independent steps” in the first paragraph of Results, as “The analysis of each single-cell transcriptome consists of several independent steps (Okray et al., 2011),” given that these points were previously raised by Okaty et al. We request to add a citation to the first paragraph of Introduction, as “studies of gene expression and function in the brain were restricted to a relatively small number of genes (Luo and Geschwind, 2001; Zhang et al., 2002; Okaty et al., 2011),” given that this points was recently reviewed in the Okaty et al., paper. More importantly, we have made a mistake in quoting sentence from Okray et al., without quotation or citation. We wish to change the following sentence:

Moreover, gene expression may be regulated in opposing directions in different cell types, thereby appearing static in composite data.

To

Moreover, as previously discussed by Okaty et al., “gene expression may be regulated in opposing directions in different cell types, thereby appearing static in composite data (Okaty et al., 2011).”

We apologize to the readers of Frontiers in Genetics and to the authors of the Okaty et al., manuscript, for our failure to correct these mistakes during the review process of our manuscript.

References

  • 1

    LuoZ.GeschwindD. H. (2001). Microarray applications in neuroscience. Neurobiol. Dis. 8, 183193. 10.1006/nbdi.2001.0387

  • 2

    OkatyB. W.SuginoK.NelsonS. B. (2011). Cell type-specific transcriptomics in the brain. J. Neurosci. 31, 69396943. 10.1523/JNEUROSCI.0626-11.2011

  • 3

    ZhangW.WangH.SongS. W.FullerG. N. (2002). Insulin-likegrowth factor binding protein 2: gene expression microarrays and the hypothesis-generation paradigm. Brain Pathol. 12, 8794.

Summary

Keywords

RNA-Seq, Neuron, single cell, Reproducibility of Results, Single-neuron diversity

Citation

Qiu S, Luo S, Evgrafov O, Li R, Schroth GP, Levitt P, Knowles JA and Wang K (2013) Erratum: Single-neuron RNA-Seq: technical feasibility and reproducibility. Front. Genet. 4:23. doi: 10.3389/fgene.2013.00023

Received

09 January 2013

Accepted

12 February 2013

Published

27 February 2013

Volume

4 - 2013

Edited by

Paul Pavlidis, University of British Columbia, Canada

Copyright

*Correspondence: ;

This article was submitted to Frontiers in Neurogenomics, a specialty of Frontiers in Genetics.

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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