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CORRECTION article

Front. Genet., 22 September 2021
Sec. RNA
This article is part of the Research Topic RNA editing and modification in development and diseases View all 13 articles

Corrigendum: Histone Deacetylase 3 Aggravates Type 1 Diabetes Mellitus by Inhibiting Lymphocyte Apoptosis Through the microRNA-296-5p/Bcl-xl Axis

\nQibo HuQibo HuGuanghua CheGuanghua CheYu YangYu YangHongchang XieHongchang XieJing Tian
Jing Tian*
  • Department of Pediatrics, The Second Hospital of Jilin University, Changchun, China

A Corrigendum on
Histone Deacetylase 3 Aggravates Type 1 Diabetes Mellitus by Inhibiting Lymphocyte Apoptosis Through the microRNA-296-5p/Bcl-xl Axis

by Hu, Q., Che, G., Yang, Y., Xie, H., and Tian J. (2020). Front. Genet. 11:536854. doi: 10.3389/fgene.2020.536854

In the original article, there was a mistake in Table 1 as published. We misplaced the forward primer and reverse primer when typesetting, which has been adjusted. The corrected Table 1 appears below.

TABLE 1
www.frontiersin.org

Table 1. Primer sequences used in RT-qPCR analysis.

Additionally, there was also a mistake in the text of the published article. We are sorry that the previous method description was not clear enough. Now we have modified the related method description: “For reverse transcription (RT) of mRNA, 1 μg of RNA was synthesized into cDNA at 42°C for 50 min by using the TaqMan RT reagent (Roche, Canton of Basel, Switzerland). For the RT of miRNA, specific stem-loop primers were used to synthesize cDNA.”

A correction has been made to Methods, RNA Isolation and Quantitation, Paragraph 1:

Total RNA from tissues or cells was extracted using the miRNeasy Mini kit (QIAGEN, GmbH, Hilden, Germany) and subsequently quantified using NanoDrop ND-1000 Spectrophotometer (NanoDrop Products, Wilmington, DE, USA), whereas RNA integrity was evaluated by microfluidic electrophoresis. For reverse transcription (RT) of mRNA, 1 μg of RNA was synthesized into cDNA at 42°C for 50 min by using the TaqMan RT reagent (Roche, Canton of Basel, Switzerland). For the RT of miRNA, specific stem-loop primers were used to synthesize cDNA.

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's Note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: histone deacetylase 3, microRNA-296-5p, B-cell leukemia-XL, type 1 diabetes mellitus, peripheral blood mononuclear cells, apoptosis

Citation: Hu Q, Che G, Yang Y, Xie H and Tian J (2021) Corrigendum: Histone Deacetylase 3 Aggravates Type 1 Diabetes Mellitus by Inhibiting Lymphocyte Apoptosis Through the microRNA-296-5p/Bcl-xl Axis. Front. Genet. 12:715061. doi: 10.3389/fgene.2021.715061

Received: 26 May 2021; Accepted: 24 August 2021;
Published: 22 September 2021.

Edited and reviewed by: Peter G. Zaphiropoulos, Karolinska Institutet (KI), Sweden

Copyright © 2021 Hu, Che, Yang, Xie and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Jing Tian, eGlhb2ppbmc4MDAxMjAmI3gwMDA0MDtqbHUuZWR1LmNu

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.