BRIEF RESEARCH REPORT article

Front. Genet.

Sec. Immunogenetics

Identification of a Novel HLA-G Allele, HLA-G*01:66, Using PolyseqOne and Oxford Nanopore Sequencing

  • 1. Shenzhen Blood Center, Shenzhen, China

  • 2. The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China

The final, formatted version of the article will be published soon.

Abstract

HLA-G*01:66 differs from HLA-G*01:01:22:01 by one missense nucleotide substitution at position 508 in exon 3.

Summary

Keywords

Codon, HLA-G, Mutation, nanopore sequencing, Novel allele

Received

13 January 2026

Accepted

20 February 2026

Copyright

© 2026 LI, Sun and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Siqi Cai

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