Frontiers in Genetics

Original Research

Published on 07 Apr 2025

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

in Cancer Genetics and Oncogenomics

Li Ning
Xiu Li
Yating Xu
Yu Si
Hongting Zhao
Qinling Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1532523

3,072 views
1 citation

Original Research

Published on 07 Apr 2025

LncRNA H19 promotes adipogenic differentiation disorder by sponging miR-130b-3p to upregulate PPARγ in steroid-induced osteonecrosis of the femoral head

in RNA

Feifei Lin
Min Yi
Shicheng Zhou
Qingyu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1529797

2,164 views
1 citation

Original Research

Published on 07 Apr 2025

SAMHD1 knockout hiPSC model enables high lentiviral transduction efficiency in myeloid cell types

in Stem Cell Research

Huinan Li
Maliha Afroze
Gunisha Arora
Scot Federman
Kaivalya Shevade
Yeqing Angela Yang
Phuong Nguyen
Rustam Esanov
Laralynne Przybyla
Adam Litterman

Frontiers in Genetics

doi 10.3389/fgene.2025.1574545

3,401 views
1 citation

Case Report

Published on 07 Apr 2025

A novel DNM2 variant associated with centronuclear myopathy: a case report

in Genetics of Common and Rare Diseases

Martina Rimoldi
Daniele Velardo
Simona Zanotti
Michela Ripolone
Roberto Del Bo
Patrizia Ciscato
Laura Napoli
Stefania Corti
Giacomo Pietro Comi
Dario Ronchi

Frontiers in Genetics

doi 10.3389/fgene.2025.1559773

2,773 views

Editorial

Published on 04 Apr 2025

Editorial: Methylation in the human brain

in Behavioral and Psychiatric Genetics

Sheila T. Nagamatsu
Francisco Navarrete
Maria S. Garcia-Gutierrez

Frontiers in Genetics

doi 10.3389/fgene.2025.1589816

3,132 views
1 citation

Original Research

Published on 04 Apr 2025

Checkpoint and recombination pathways independently suppress rates of spontaneous homology-directed chromosomal translocations in budding yeast

in Predictive Toxicology and Exposomics

Li Zeng
Mingzeng Sun
Michael Fasullo

Frontiers in Genetics

doi 10.3389/fgene.2025.1479307

3,236 views

Original Research

Published on 04 Apr 2025

Hypergraph-based analysis of weighted gene co-expression hypernetwork

in Computational Genomics

Libing Bai
Zongjin Li
Chunyang Tang
Changxin Song
Feng Hu

Frontiers in Genetics

doi 10.3389/fgene.2025.1560841

3,489 views
4 citations

Original Research

Published on 04 Apr 2025

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients

in Cancer Genetics and Oncogenomics

Zhe Chen
Lina Ding
Jieni Yu
Jing Jin
Zhijian Zhang
Jiaping Fu
Pan Hong
Leihua Fu

Frontiers in Genetics

doi 10.3389/fgene.2025.1524177

2,319 views

Original Research

Published on 04 Apr 2025

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Jian Xiao
Wei Li
Guolin Tan
Ru Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1540841

2,441 views

Original Research

Published on 04 Apr 2025

Transcriptomic signature can distinguish chronic neutrophilic leukemia from ambiguous neutrophilic leukemias

in Cancer Genetics and Oncogenomics

Chao Guo
Zhen-Ling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1556519

2,139 views

Correction

Published on 03 Apr 2025

Corrigendum: Comprehensive profiling reveals distinct microenvironment and metabolism characterization of lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Chang Li
Chen Tian
Yangyang Liu
Jinyan Liang
Yulan Zeng
Qifan Yang
Yuting Liu
Di Wu
Jingjing Wu
Juanjuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1585016

1,185 views

Original Research

Published on 03 Apr 2025

Role of lactylation and immune infiltration in atherosclerosis: novel insights from bioinformatics analyses

in Computational Genomics

Jintao Qian
Qing Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1520325

4,799 views
2 citations

Original Research

Published on 02 Apr 2025

Enhanced renal ischemia/reperfusion injury repair potential of exosomes derived from B7-H1high mesenchymal stem cells

in Stem Cell Research

Jiahui He
Yawei Yao
Ruiyan Wang
Yujia Liu
Xingyu Wan
Hao Wang
Yuqiang Zhou
Wenjing Wang
Yan Ma
Xinghua Lv

Frontiers in Genetics

doi 10.3389/fgene.2025.1516626

3,004 views
1 citation

Original Research

Published on 02 Apr 2025

Improving accuracy and precision of heritability estimation in twin studies through hierarchical modeling: reassessing the measurement error assumption

in Behavioral and Psychiatric Genetics

Gang Chen
Dustin Moraczewski
Paul A. Taylor

Frontiers in Genetics

doi 10.3389/fgene.2025.1522729

3,988 views

Brief Research Report

Published on 02 Apr 2025

Optical genome mapping with whole genome sequencing identifies complex chromosomal structural variations in acute leukemia

in Genomic Assay Technology

Meng-Ju Melody Tsai
Hsiao-Jung Kao
Hsiao-Huei Chen
Chih-Hsiang Yu
Yin-Hsiu Chien
Wuh-Liang Hwu
Pui-Yan Kwok
Ni-Chung Lee
Yung-Li Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1496847

4,476 views
2 citations

Original Research

Published on 02 Apr 2025

Thyroid function and hepatic fibrosis/cirrhosis: a two-sample Mendelian randomization study

in Statistical Genetics and Methodology

Yan Wang
XiaoLi Zhang
Qin Li
Qing Zhang
Jun Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1399353

2,889 views

Review

Published on 02 Apr 2025

Life destiny of erythrocyte in high altitude erythrocytosis: mechanisms underlying the progression from physiological (moderate) to pathological (excessive) high-altitude erythrocytosis

in Human and Medical Genomics

Xiaoying Zhou
Quanwei Bao
Yu Cui
Xiaoxu Li
Chengzhong Yang
Yidong Yang
Yuqi Gao
Dewei Chen
Jian Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1528935

5,129 views
5 citations

Original Research

Published on 02 Apr 2025

Exploration of folate and its derivatives in grains of wheat with different colors

in Genomics of Plants and the Phytoecosystem

Peng Tian
Yangna Liu
Yingli Cheng
Bin Yang
Yuzhi Wang
Bangbang Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1549122

2,289 views

Original Research

Published on 01 Apr 2025

Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma

in Computational Genomics

Lichao Cao
Haoyang Dai
Shangqing Wei
Ying Ba
Fang Chen
Yingying Chen
Chendi Yu
Shenrui Zhang
Erfei Chen
Hezi Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1516232

2,780 views

Methods

Published on 31 Mar 2025

A method for finding epistatic effects of maternal and fetal variants

in Statistical Genetics and Methodology

Michael Nodzenski
Min Shi
David M. Umbach
Brian Kidd
Taylor Petty
Clarice R. Weinberg

Frontiers in Genetics

doi 10.3389/fgene.2025.1420641

1,946 views

Original Research

Published on 31 Mar 2025

Identification of a novel nonsense mutation and a recurrent missense mutation in UROS gene in a patient with congenital erythropoietic porphyria

in Genetics of Common and Rare Diseases

Ning Jia
Yusupu Yimin
Ming Li
Long Jiang
Yeqiang Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1486595

2,065 views

Original Research

Published on 31 Mar 2025

De novo KCNK4 variant caused epilepsy with febrile seizures plus, neurodevelopmental abnormalities, and hypertrichosis

in Computational Genomics

Hong-Jun Yan
Wen-Hui Liu
Min-Xing Xu
Peng-Yu Wang
Yu-Jie Gu
Hua Li
Jing Guo
Sheng Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1499716

2,834 views
4 citations

Original Research

Published on 28 Mar 2025

Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer

in Cancer Genetics and Oncogenomics

Ajay Kumar Saw
Ayush Madhok
Anupam Bhattacharya
Soumyadeep Nandi
Sanjeev Galande

Frontiers in Genetics

doi 10.3389/fgene.2025.1553469

5,046 views

Original Research

Published on 28 Mar 2025

Differentially expressed and alternately spliced genes as a novel tool for genotoxicity: a computerized study in ATT-myc transgenic mice for the recognition of genotoxic and non-genotoxic chemical

in Predictive Toxicology and Exposomics

Mansour A. Alghamdi
Eman M. El Nashar
Mahmoud Elalfy
Norah S. Al-Zahrani
Mohammed A. Alshehri
Mohammad El-Nablaway
Khulood M. Al-Khater
Rashid A. Aldahhan
Eman G. El-Hadidy
Fathy Sleem

Frontiers in Genetics

doi 10.3389/fgene.2025.1505379

3,195 views

16,551 articles

articles

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

LncRNA H19 promotes adipogenic differentiation disorder by sponging miR-130b-3p to upregulate PPARγ in steroid-induced osteonecrosis of the femoral head

SAMHD1 knockout hiPSC model enables high lentiviral transduction efficiency in myeloid cell types

A novel DNM2 variant associated with centronuclear myopathy: a case report

Editorial: Methylation in the human brain

Checkpoint and recombination pathways independently suppress rates of spontaneous homology-directed chromosomal translocations in budding yeast

Hypergraph-based analysis of weighted gene co-expression hypernetwork

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

Transcriptomic signature can distinguish chronic neutrophilic leukemia from ambiguous neutrophilic leukemias

Corrigendum: Comprehensive profiling reveals distinct microenvironment and metabolism characterization of lung adenocarcinoma

Role of lactylation and immune infiltration in atherosclerosis: novel insights from bioinformatics analyses

Enhanced renal ischemia/reperfusion injury repair potential of exosomes derived from B7-H1high mesenchymal stem cells

Improving accuracy and precision of heritability estimation in twin studies through hierarchical modeling: reassessing the measurement error assumption

Optical genome mapping with whole genome sequencing identifies complex chromosomal structural variations in acute leukemia

Thyroid function and hepatic fibrosis/cirrhosis: a two-sample Mendelian randomization study

Life destiny of erythrocyte in high altitude erythrocytosis: mechanisms underlying the progression from physiological (moderate) to pathological (excessive) high-altitude erythrocytosis

Exploration of folate and its derivatives in grains of wheat with different colors

Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma

A method for finding epistatic effects of maternal and fetal variants

Identification of a novel nonsense mutation and a recurrent missense mutation in UROS gene in a patient with congenital erythropoietic porphyria

De novo KCNK4 variant caused epilepsy with febrile seizures plus, neurodevelopmental abnormalities, and hypertrichosis

Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer

Differentially expressed and alternately spliced genes as a novel tool for genotoxicity: a computerized study in ATT-myc transgenic mice for the recognition of genotoxic and non-genotoxic chemical