Frontiers in Genetics | Computational Genomics

Original Research

Published on 23 Aug 2022

An integrative analysis revealing POLD2 as a tumor suppressive immune protein and prognostic biomarker in pan-cancer

in Computational Genomics

Fengyun Cong
Junxian Long
Jun Liu
Zhixiang Deng
Binli Yan
Cao Liang
Xiaoliang Huang
Jinxin Liu
Weizhong Tang

Frontiers in Genetics

doi 10.3389/fgene.2022.877468

3,541 views
2 citations

Original Research

Published on 23 Aug 2022

Mutational signatures representative transcriptomic perturbations in hepatocellular carcinoma

in Computational Genomics

Qiong Wu
Lingyi Wang
Stephen Kwok-Wing Tsui

Frontiers in Genetics

doi 10.3389/fgene.2022.970907

2,374 views
1 citation

Original Research

Published on 22 Aug 2022

Clustering CITE-seq data with a canonical correlation-based deep learning method

in Computational Genomics

Musu Yuan
Liang Chen
Minghua Deng

Frontiers in Genetics

doi 10.3389/fgene.2022.977968

4,286 views
5 citations

Original Research

Published on 22 Aug 2022

AttnTAP: A Dual-input Framework Incorporating the Attention Mechanism for Accurately Predicting TCR-peptide Binding

in Computational Genomics

Ying Xu
Xinyang Qian
Yao Tong
Fan Li
Ke Wang
Xuanping Zhang
Tao Liu
Jiayin Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.942491

3,160 views
14 citations

Original Research

Published on 22 Aug 2022

Dynamic transcriptome analysis suggests the key genes regulating seed development and filling in Tartary buckwheat (Fagopyrum tataricum Garetn.)

in Computational Genomics

Liangzhen Jiang
Changying Liu
Yu Fan
Qi Wu
Xueling Ye
Qiang Li
Yan Wan
Yanxia Sun
Liang Zou
Dabing Xiang

Frontiers in Genetics

doi 10.3389/fgene.2022.990412

2,400 views
15 citations

Original Research

Published on 22 Aug 2022

Predict potential miRNA-disease associations based on bounded nuclear norm regularization

in Computational Genomics

Yidong Rao
Minzhu Xie
Hao Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.978975

1,198 views
2 citations

Original Research

Published on 17 Aug 2022

Integrating cell cycle score for precise risk stratification in ovarian cancer

in Computational Genomics

Lingying Chen
Haiyan Gu
Lei Zhou
Jingna Wu
Changdong Sun
Yonggui Han

Frontiers in Genetics

doi 10.3389/fgene.2022.958092

2,074 views
2 citations

Original Research

Published on 17 Aug 2022

Molecular characteristics of immunocytes infiltration in primary central nervous system lymphoma

in Computational Genomics

Linyun Zhang
Fei Sun
Xiaona Lu
Xiaotong Wang
Jie Wang
Jun Li
Yingsong Xu
Daqing Kou
Hongtao Lv
Bin Don

Frontiers in Genetics

doi 10.3389/fgene.2022.921823

2,796 views
1 citation

Opinion

Published on 17 Aug 2022

The rise of hierarchy and modularity in biological networks explained by Empedocles’ double tale ∼2,400 years before Darwin and systems biology

in Computational Genomics

Gustavo Caetano-Anollés
Richard Janko

Frontiers in Genetics

doi 10.3389/fgene.2022.973233

1,976 views
4 citations

Correction

Published on 17 Aug 2022

Corrigendum: Developing an immune-related signature for predicting survival rate and the response to immune checkpoint inhibitors in patients with glioma

in Computational Genomics

Sibin Zhang
Xu Xiao
Yu Wang
Tianjun Song
Chenlong Li
Hongbo Bao
Qing Liu
Guiyin Sun
Xiaoyang Sun
Tianqi Su

Frontiers in Genetics

doi 10.3389/fgene.2022.961153

1,439 views

Original Research

Published on 16 Aug 2022

KGDCMI: A New Approach for Predicting circRNA–miRNA Interactions From Multi-Source Information Extraction and Deep Learning

in Computational Genomics

Xin-Fei Wang
Chang-Qing Yu
Li-Ping Li
Zhu-Hong You
Wen-Zhun Huang
Yue-Chao Li
Zhong-Hao Ren
Yong-Jian Guan

Frontiers in Genetics

doi 10.3389/fgene.2022.958096

3,827 views
34 citations

Original Research

Published on 16 Aug 2022

Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis

in Computational Genomics

Mohammed Y. Behairy
Mohamed A. Soltan
Mohamed S. Adam
Ahmed M. Refaat
Ehab M. Ezz
Sarah Albogami
Eman Fayad
Fayez Althobaiti
Ahmed M. Gouda
Ashraf E. Sileem

Frontiers in Genetics

doi 10.3389/fgene.2022.872845

5,358 views
12 citations

Original Research

Published on 16 Aug 2022

Integrated analysis of necroptosis-related lncRNAs for prognosis and immunotherapy of patients with pancreatic adenocarcinoma

in Computational Genomics

Jiantao Mo
Zhiwei Cui
Qiqi Wang
Weifan Zhang
Jie Li
Shuai Wu
Weikun Qian
Cancan Zhou
Qingyong Ma
Zheng Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.940794

2,700 views
2 citations

Original Research

Published on 15 Aug 2022

Single-cell RNA sequencing analysis to explore immune cell heterogeneity and novel biomarkers for the prognosis of lung adenocarcinoma

in Computational Genomics

Yong Xu
Yao Wang
Leilei Liang
Nan Song

Frontiers in Genetics

doi 10.3389/fgene.2022.975542

5,174 views
9 citations

Methods

Published on 15 Aug 2022

A method for identifying moonlighting proteins based on linear discriminant analysis and bagging-SVM

in Computational Genomics

Yu Chen
Sai Li
Jifeng Guo

Frontiers in Genetics

doi 10.3389/fgene.2022.963349

2,218 views
9 citations

Original Research

Published on 15 Aug 2022

Using expression quantitative trait loci data and graph-embedded neural networks to uncover genotype–phenotype interactions

in Computational Genomics

Xinpeng Guo
Jinyu Han
Yafei Song
Zhilei Yin
Shuaichen Liu
Xuequn Shang

Frontiers in Genetics

doi 10.3389/fgene.2022.921775

2,639 views
2 citations