Frontiers in Genetics | Computational Genomics

Original Research

Published on 28 Oct 2024

TargetCall: eliminating the wasted computation in basecalling via pre-basecalling filtering

in Computational Genomics

Meryem Banu Cavlak
Gagandeep Singh
Mohammed Alser
Can Firtina
Joël Lindegger
Mohammad Sadrosadati
Nika Mansouri Ghiasi
Can Alkan
Onur Mutlu

Frontiers in Genetics

doi 10.3389/fgene.2024.1429306

1,040 views
1 citation

Methods

Published on 25 Oct 2024

GTasm: a genome assembly method using graph transformers and HiFi reads

in Computational Genomics

Junwei Luo
Ziheng Zhang
Xinliang Ma
Chaokun Yan
Huimin Luo

Frontiers in Genetics

doi 10.3389/fgene.2024.1495657

1,811 views

Original Research

Published on 22 Oct 2024

Dinucleotide composition representation -based deep learning to predict scoliosis-associated Fibrillin-1 genotypes

in Computational Genomics

Sen Zhang
Li-Na Dai
Qi Yin
Xiao-Ping Kang
Dan-Dan Zeng
Tao Jiang
Guang-Yu Zhao
Xiao-He Li
Jing Li

Frontiers in Genetics

doi 10.3389/fgene.2024.1492226

1,342 views

Original Research

Published on 16 Oct 2024

Identification of potential therapeutic targets for systemic lupus erythematosus based on GEO database analysis and Mendelian randomization analysis

in Computational Genomics

Aishanjiang Apaer
Yanyan Shi
Alimijiang Aobulitalifu
Fujie Wen
Adalaiti Muhetaer
Nuermaimaiti Ajimu
Maierhaba Sulitan
Lei Cheng

Frontiers in Genetics

doi 10.3389/fgene.2024.1454486

4,334 views
2 citations

Original Research

Published on 02 Oct 2024

TCRcost: a deep learning model utilizing TCR 3D structure for enhanced of TCR–peptide binding

in Computational Genomics

Fan Li
Xinyang Qian
Xiaoyan Zhu
Xin Lai
Xuanping Zhang
Jiayin Wang

Frontiers in Genetics

doi 10.3389/fgene.2024.1346784

1,429 views
2 citations

Original Research

Published on 01 Oct 2024

Transparent sparse graph pathway network for analyzing the internal relationship of lung cancer

in Computational Genomics

Zhibin Jin
Yuhu Shi
Lili Zhou

Frontiers in Genetics

doi 10.3389/fgene.2024.1437174

909 views

Original Research

Published on 20 Sep 2024

Genomic analysis and mechanisms exploration of a stress tolerance and high-yield pullulan producing strain

in Computational Genomics

Jing Yang
Ning Sun
Wenru Wang
Ruihua Zhang
Siqi Sun
Biqi Li
Yue Shi
Junfeng Zeng
Shulei Jia

Frontiers in Genetics

doi 10.3389/fgene.2024.1469600

1,804 views

Retraction

Published on 20 Sep 2024

Retraction: Mitochondrial-associated protein LRPPRC is related with poor prognosis potentially and exerts as an oncogene via maintaining mitochondrial function in pancreatic cancer

in Computational Genomics

Frontiers Editorial Office

Frontiers in Genetics

doi 10.3389/fgene.2024.1495469

837 views

Original Research

Published on 20 Sep 2024

DGDRP: drug-specific gene selection for drug response prediction via re-ranking through propagating and learning biological network

in Computational Genomics

Minwoo Pak
Dongmin Bang
Inyoung Sung
Sun Kim
Sunho Lee

Frontiers in Genetics

doi 10.3389/fgene.2024.1441558

2,593 views
1 citation

Original Research

Published on 20 Sep 2024

CSER: a gene regulatory network construction method based on causal strength and ensemble regression

in Computational Genomics

Yujia Li
Yang Du
Mingmei Wang
Dongmei Ai

Frontiers in Genetics

doi 10.3389/fgene.2024.1481787

1,236 views

Review

Published on 19 Sep 2024

Methods for multi-omic data integration in cancer research

in Computational Genomics

Enrique Hernández-Lemus
Soledad Ochoa

Frontiers in Genetics

doi 10.3389/fgene.2024.1425456

5,200 views
3 citations

Original Research

Published on 18 Sep 2024

Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease

in Computational Genomics

Na Wang
Jun Liu
Bao Chai
Jianhong Yao
Xufang Du
Qi Mei
Xuena Wang

Frontiers in Genetics

doi 10.3389/fgene.2024.1436407

1,687 views

Original Research

Published on 18 Sep 2024

Identification of novel targets associated with cholesterol metabolism in nonalcoholic fatty liver disease: a comprehensive study using Mendelian randomization combined with transcriptome analysis

in Computational Genomics

Juan Chen
Huajing Rao
Xiaoling Zheng

Frontiers in Genetics

doi 10.3389/fgene.2024.1464865

3,002 views
2 citations

Original Research

Published on 18 Sep 2024

Integrative multi-omics summary-based mendelian randomization identifies key oxidative stress-related genes as therapeutic targets for atrial fibrillation and flutter

in Computational Genomics

Shijian Chen
Junlong Sun
Wen Wen
Zhenfeng Chen
Ziheng Yu

Frontiers in Genetics

doi 10.3389/fgene.2024.1447872

3,809 views
3 citations

Original Research

Published on 16 Sep 2024

Graph neural pre-training based drug-target affinity prediction

in Computational Genomics

Qing Ye
Yaxin Sun

Frontiers in Genetics

doi 10.3389/fgene.2024.1452339

1,645 views

Review

Published on 13 Sep 2024

Transcriptional bursting dynamics in gene expression

in Computational Genomics

Qiuyu Zhang
Wenjie Cao
Jiaqi Wang
Yihao Yin
Rui Sun
Zunyi Tian
Yuhan Hu
Yalan Tan
Ben-gong Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1451461

4,046 views
2 citations