Frontiers in Genetics | Computational Genomics

Original Research

Accepted on 09 Jul 2025

Identification of biomarkers between coronary artery disease and nonalcoholic steatohepatitis: A combination of bioinformatics and machine learning

in Computational Genomics

Yihong Lin
Jingmei Song
Xiaohong Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1573621

104 views

Original Research

Accepted on 09 Jul 2025

Multi-omic Insights into Mitochondrial Dysfunction and Prostatic Disease: Evidence from Transcriptomics, Proteomics, and Methylomics

in Computational Genomics

Binbin Gong
Feixiang Yang
Ning Zhang
Zhengyang Wu
Kun Wang
Kun Wang
Xiangyu Zhang
Yangyang Zhang
Zhengyao Song
Chaozhao Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609933

Original Research

Accepted on 07 Jul 2025

DeepRNAac4C: A Hybrid Deep Learning Framework for RNA N4-Acetylcytidine Site Prediction

in Computational Genomics

Guohua Huang
Runjuan Xiao
Chunyin Peng
Jinyun Jiang
WeiHong Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1622899

132 views

Original Research

Published on 07 Jul 2025

Geometry-enhanced graph neural networks accelerate circRNA therapeutic target discovery

in Computational Genomics

Zhen Li
Mingming Qi
Juyuan Huang
Wei Zhang
Xu Tan
Yifan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1633391

380 views

Original Research

Accepted on 03 Jul 2025

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

in Computational Genomics

Cui Xu
Houlin JI
Shengyang Guo
Ju LIU
Linyuan ZHANG
Yongwei JIA
Ying CUI
Xiaoxiao ZHOU

Frontiers in Genetics

doi 10.3389/fgene.2025.1595676

245 views

Original Research

Accepted on 02 Jul 2025

EPI-DynFusion: Enhancer-Promoter Interaction Prediction Model Based on Sequence Features and Dynamic Fusion Mechanisms

in Computational Genomics

Ao Zhang
Jianhua Jia
Mingwei Sun
Xin Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1614222

128 views

Original Research

Published on 02 Jul 2025

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

in Computational Genomics

Yisong Sun
Jie Gao
Juehua Jing

Frontiers in Genetics

doi 10.3389/fgene.2025.1609439

327 views

Original Research

Accepted on 27 Jun 2025

Incorporating Graph Representation and Mutual Attention Mechanism for MiRNA-MRNA Interaction Prediction

in Computational Genomics

Tailong Shi
Lei Wang
Liguang Huang
Zhu-Hong You
ChangQing Yu
Chen Jiang
Sizhe Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1637427

196 views

Original Research

Published on 26 Jun 2025

HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction

in Computational Genomics

Fuyu Li
Wenxiang Lu
Yunfei Bai

Frontiers in Genetics

doi 10.3389/fgene.2025.1641162

521 views

Original Research

Published on 25 Jun 2025

A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data

in Computational Genomics

Fengchun Ren
Xiao Zhao
Qin Yang
Huaqiang Liao
Yudong Zhang
Xuemei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1631228

655 views

Methods

Accepted on 24 Jun 2025

Robust Consensus Nuclear and Cell Segmentation

in Computational Genomics

Melis Omer Irfan
Eduardo A Gonz Ález-Solares
Tristan Whitmarsh
Alireza Molaeinezhad
Mohammad Al Sa'd
Claire M Mulvey
Marta P Áez Ribes
Dario Bressan
Nicholas A Walton

Frontiers in Genetics

doi 10.3389/fgene.2025.1547788

133 views

Original Research

Accepted on 24 Jun 2025

A bioinformatics analysis on the correlation between hepatic ischemiareperfusion injury and postoperative cognitive dysfunction

in Computational Genomics

Qing Hu
Haijie Liu
Yunfei Bao
Zhihao Feng
Hongbo Zhang
Jianling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1607446

116 views

Methods

Accepted on 24 Jun 2025

A Likelihood Ratio Framework for Inferring Close Kinship from Dynamically Selected SNPs

in Computational Genomics

Jianye Ge
Bruce Budowle
Michael Cariaso
Kristen Mittelman
David Mittelman

Frontiers in Genetics

doi 10.3389/fgene.2025.1635734

210 views

Original Research

Published on 24 Jun 2025

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

in Computational Genomics

Yingnan Li
Ning Xiao
Zhuoqun Wang
Wenhai Wang
Fengjiao Li
Jiren Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1620749

803 views

Original Research

Published on 23 Jun 2025

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

in Computational Genomics

Jingya Xu
Zhonghua Dong
Zhaodong Li
Xuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1592985

754 views

Original Research

Published on 23 Jun 2025

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

in Computational Genomics

Xudong Wu
Tingting Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544802

758 views