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ORIGINAL RESEARCH article

Front. Glob. Women’s Health

Sec. Contraception and Family Planning

Volume 6 - 2025 | doi: 10.3389/fgwh.2025.1552379

Setbacks in the road to self-injection: a descriptive study of provider and mystery client reports on the DMPA-SC care-seeking experience in Nigeria

Provisionally accepted
Madeline  GriffithMadeline Griffith1*Sneha  ChallaSneha Challa1Ayobambo  JegedeAyobambo Jegede2Ivan  IdiodiIvan Idiodi2Chioma  OkoliChioma Okoli2Aminat  TijaniAminat Tijani2Shakede  DimowoShakede Dimowo2Awawu  Grace NmaduAwawu Grace Nmadu2Elizabeth  OmoluabiElizabeth Omoluabi2Jenny  LiuJenny Liu1
  • 1University of California, San Francisco, San Francisco, United States
  • 2AkenaPlus Health, Abuja, Nigeria

The final, formatted version of the article will be published soon.

This mixed-methods study describes perspectives from health providers and simulated clients on initiation and continuation of DMPA-SC for self-injection in Nigeria. Through mystery (simulated) client interactions, we found that providers were similarly willing to dispense units of DMPA-SC for selfinjection to different client profiles, which varied in age, marital status, and parity. However, in-depth interviews with providers revealed nuance in their approaches to assessing clients' eligibility for unsupervised self-injection of DMPA-SC. Factors including client age, marital status, parity, and education influenced who they deemed able to self-inject, which may limit access to DMPA-SC for clients who wish to self-inject the method. Quantitative and qualitative data also indicated that clients faced setbacks in continuing unsupervised self-injection when seeking refills from an unfamiliar provider. Stockouts of DMPA-SC further complicated access; some providers resorted to purchasing DMPA-SC privately and passing the cost onto clients. These findings highlight the need for clearer refill protocols and more consistent supply to ensure equitable access to DMPA-SC for self-injection in Nigeria.Research has tracked the implementation and scale-up of DMPA-SC since the introduction of the method in Nigeria in 2015. Sieverding et al. first described the method initiation experience with a mystery client (MC) study in 2016 in South West Nigeria, which found provider bias in contraceptive provision to adolescents and young women (9). Despite the potential benefits of self-injection of DMPA-SC to empower self-care, persistent barriers hinder women's ability to initiate and continue using DMPA-SC, including the ability to reliably find and obtain refills. Structural barriers, including method availability, cost, and the multi-step dispensing guidelines, complicate method initiation and continuation for both providers and clients, as noted in Nigeria's National Guidelines for the

Keywords: Self-injection, self-care, DMPA-SC, implementation research, mixed-methods, refills, method continuation

Received: 27 Dec 2024; Accepted: 23 Jul 2025.

Copyright: © 2025 Griffith, Challa, Jegede, Idiodi, Okoli, Tijani, Dimowo, Nmadu, Omoluabi and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Madeline Griffith, University of California, San Francisco, San Francisco, United States

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