ORIGINAL RESEARCH article
Front. Mar. Sci.
Sec. Aquatic Microbiology
Volume 12 - 2025 | doi: 10.3389/fmars.2025.1689231
This article is part of the Research TopicMicrobial Diversity and Survival Strategies in Polar EnvironmentsView all articles
Proteomics and metabolic profiling of Vibrio parahaemolyticus at three different temperatures
Provisionally accepted
- Hainan Academy of Ocean and Fisheries Sciences, Haikou, China
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ABSTRACT Microorganisms exist and survive in complex and variable environments. Bacteria communities response and adapt to the changing conditions. The Mechanisms underlying bacterial survival can be elucidated through the use of multi-omics techniques. Here, we test an approach for measuring how different temperatures (4°C, 25°C, and 37°C)affected bacterial physiological functions. Proteomic and metabolomic analyses were conducted on Vibrio parahaemolyticus LF1113 under different temperatures, identifying a total of 2,899 proteins and 396 metabolites. The differentially expressed proteins (DEPs) and differentially metabolites (DMs) were involved in Lysine degradation, metabolic pathways, ABC transporters, and microbial metabolism in diverse environments pathways. An integrated metabolomics/proteomics analysis approach was employed in this study. The analysis of both types of data information (proteins and metabolites) aids to reveal the microbial adaptive regulation in response to temperature stimuli. The study can further help clinical research of V. parahaemolyticus from the perspective of metabolomics and proteomics.
Keywords: Vibrio parahaemolyticus, temperature, Proteomics, Metabolomics, Correlation
Received: 20 Aug 2025; Accepted: 30 Sep 2025.
Copyright: © 2025 Meng, Tu, Hu and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Linlin Hu, 442954558@qq.com
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