CASE REPORT article
Front. Med.
Sec. Obstetrics and Gynecology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1576161
Successful perinatal management in pregnant women with R9 limb-girdle muscular dystrophy with a left ventricular ejection fraction of 27%: A case report
Provisionally accepted
- 1Southwest Medical University, Luzhou, Sichuan, China
- 2University of Electronic Science and Technology of China, Chengdu, Sichuan Province, China
- 3Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan Province, China
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A 29-year-old patient with muscle weakness at 26+5 weeks of pregnancy was hospitalized for heart failure, and genetic testing revealed that she had R9 limb-girdle muscular dystrophy (LGMDR9). Because LGMDR9 is associated with cardiac and respiratory dysfunction, to prevent further deterioration of cardiac function and muscle weakness, we promoted fetal lung maturation and performed an emergency cesarean section at 29+2 weeks. This case highlights the importance of choosing the right mode of delivery, timing of delivery, and early genetic testing for LGMDR9 patients.
Keywords: case report, Limb-girdle muscular dystrophy, Pregnancy, cardiomyopathy, Heart Failure
Received: 13 Feb 2025; Accepted: 14 Jul 2025.
Copyright: © 2025 WENCHI, Landan, Dan, Qingquan and Jie. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Mei Jie, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, 611731, Sichuan Province, China
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