ORIGINAL RESEARCH article
Front. Med.
Sec. Ophthalmology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1596726
This article is part of the Research TopicEfficient Artificial Intelligence in Ophthalmic Imaging – Volume IIView all 8 articles
OculusNet: Detection of Retinal Diseases Using A Tailored Web-Deployed Neural Network and Saliency Maps for Explainable AI
Provisionally accepted- 1Multimedia University, Cyberjaya, Selangor Darul Ehsan, Malaysia
- 2Prince Mohammad bin Fahd University, Khobar, Saudi Arabia
- 3Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia
- 4Najran University, Najran, Saudi Arabia
- 5Örebro University, Örebro, Örebro, Sweden
- 6University of Essex, Colchester, East of England, United Kingdom
- 7Edinburgh Napier University, Edinburgh, United Kingdom
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Retinal diseases are among the leading causes of blindness globally, requiring an early detection for effective treatment. Manual interpretation of ophthalmic imaging, such as Optical Coherence Tomography (OCT), is traditionally time-consuming, prone to inconsistencies, and requires specialized ophthalmic expertise. This study introduces OculusNet, an efficient and explainable Deep learning (DL) approach to detect retinal diseases using OCT images. The proposed approach is tailored specifically for complex medical image patterns in OCTs to identify retinal disorders, such as Choroidal Neovascularization (CNV), Diabetic Macular Edema (DME), and age-related macular degeneration disorder called Drusen. The proposed model benefits from Saliency Map visualization, an Explainable AI (XAI) technique, to interpret and explain how the model reached its decisions while identifying retinal disorders. Furthermore, the proposed model is deployed on a web-page, allowing users to upload retinal OCT images and receive instant detection results. This deployment demonstrates significant potential for integration into ophthalmic departments, enhancing diagnostic accuracy and efficiency. In addition, to ensure an equitable comparison, transfer learning approach has been applied on four pre-trained models,
Keywords: Retina, Retinal disorder, Explainable AI, artificial intelligence, ophthalmic imaging, neural networks
Received: 20 Mar 2025; Accepted: 04 Jun 2025.
Copyright: © 2025 Umair, Ahmad, Saidani, Alshehri, Al Mazroa, Hanif, Ullah and Khan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Muhammad Hanif, Örebro University, Örebro, 701 82, Örebro, Sweden
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