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ORIGINAL RESEARCH article

Front. Med.

Sec. Pulmonary Medicine

Volume 12 - 2025 | doi: 10.3389/fmed.2025.1620257

This article is part of the Research TopicBridging Tradition and Future: Cutting-edge Exploration and Application of Artificial Intelligence in Comprehensive Diagnosis and Treatment of Lung DiseasesView all 9 articles

PSOA-LSTM: A Hybrid Attention-Based LSTM Model Optimized by Particle Swarm Optimization for Accurate Lung Cancer Incidence Forecasting in China (1990-2021)

Provisionally accepted
Nannan  XuNannan Xu1Guang  YangGuang Yang1Linlin  MingLinlin Ming2Jiefei  DaiJiefei Dai2Kun  ZhuKun Zhu2*
  • 1Qiqihar First Hospital/Qiqihar Hospital Affiliated to Southern Medical, qiqihar, China
  • 2The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, China

The final, formatted version of the article will be published soon.

Background: Accurate forecasting of lung cancer incidence is crucial for early prevention, effective medical resource allocation, and evidence-based policymaking.Objective: This study proposes a novel deep learning framework-PSOA-LSTM-that integrates Particle Swarm Optimization (PSO) with an attention-based Long Short-Term Memory (LSTM) network to enhance the precision of lung cancer incidence prediction.Methods: Using the Global Burden of Disease 2019 (GBD 2019) dataset, the model predicts ageand gender-specific lung cancer incidence trends for the next five years. The proposed model was compared against traditional models including ARIMA, standard LSTM, Support Vector Regression (SVR), and Random Forest (RF).The PSOA-LSTM model achieved superior performance across five key evaluation metrics: Mean Squared Error (MSE) = 0.023, Coefficient of Determination (R² ) = 0.97, Mean Absolute Error (MAE) = 0.152, Normalized Root Mean Squared Error (NRMSE) = 0.025, and Mean Absolute Percentage Error (MAPE) = 0.38%. Visualization results across 12 age groups and both genders further validated the model's ability to capture temporal trends and reduce prediction error, demonstrating enhanced generalization and robustness.The proposed PSOA-LSTM model outperforms benchmark models in predicting lung cancer incidence across demographic segments, offering a reliable decision-support tool for public health surveillance, early warning systems, and health policy formulation.

Keywords: lung cancer, Healthcare forecasting, LSTM, attention mechanism, Particle Swarm Optimization, Time-series prediction

Received: 29 Apr 2025; Accepted: 21 Jul 2025.

Copyright: © 2025 Xu, Yang, Ming, Dai and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Kun Zhu, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, China

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