ORIGINAL RESEARCH article
Front. Med.
Sec. Gastroenterology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1626767
The risk factors of bleeding after EUS-guided transmural drainage of pancreatic fluid collections: A single-center experience in China
Provisionally accepted
- The Second Hospital of Hebei Medical University, Shijiazhuang, China
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Background: Endoscopic ultrasonography(EUS) guided transmural drainage has become a first-line treatment for peripancreatic fluid collections(PFCs).Post-procedure Postoperative bleeding may lead to severe clinical outcomes.The purpose of this study was to explore thepatient-related and surgery-related factors associtated with post-EUS drainage bleedingpostoperative bleeding.: This is an observational cohort study. A total of 181 patients who underwent EUS drainage at our center between June 2019 and May 2024 were enrolled analyzed in the study. Postoperative bleeding complications were observed, and patient and operation-related data were collected. Univariate and multifactorial logistics regression were performed for the risk factors that may affect postoperative bleeding. Determine the risk factors influencing bleeding after EUS drainage.Determine the risk factors affecting postoperative bleeding.We achieved a 100% technical success rate. A total of 14 cases(7.7%) of bleeding occurred. All bleeding patients were successfully treated by conservative, endoscopic, interventional and other treatments. Logistic regression analysis showed that cyst size was an independent risk factor for bleeding after EUS-guided transmural drainage (P=0.006; OR,2.722; 95%CI,1.327-5.587).The cyst size was an independent risk factor for bleeding after PFC drainage. Slowing the rate of decline in intracystic pressure may reduce the risk of bleeding.
Keywords: EUS-guided drainage, Peripancreatic fluid collections, bleeding, Risk factors, single-center
Received: 11 May 2025; Accepted: 10 Jul 2025.
Copyright: © 2025 Li, Yu, Zhang, Du, Hou, Tian, Hou and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Senlin Hou, The Second Hospital of Hebei Medical University, Shijiazhuang, China
Lichao Zhang, The Second Hospital of Hebei Medical University, Shijiazhuang, China
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