CASE REPORT article
Front. Med.
Sec. Pathology
Volume 12 - 2025 | doi: 10.3389/fmed.2025.1633085
This article is part of the Research TopicNational Cancer Research Month 2025: Advances in Detection, Treatment and Therapies in OncologyView all 9 articles
Diagnostic Challenges in Breast Carcinosarcoma: A Case Report of a Rare and Aggressive Tumor
Provisionally accepted
- First Affiliated Hospital of Jilin University, Changchun, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
This case report describes a rare breast carcinosarcoma in a 44-year-old female, highlighting the diagnostic challenges encountered across multiple hospitals. The case illustrates the difficulties in achieving a definitive diagnosis despite extensive imaging and pathological evaluations. It underscores the importance of considering breast carcinosarcoma in complex cases and the need for early, accurate diagnosis to guide effective treatment.The datasets generated during this case report are not publicly available due to patient privacy concerns. However, the clinical details and diagnostic challenges described in the manuscript are fully transparent to the authors and have been thoroughly documented for research purposes Abstract： Background and Objectives: Breast carcinosarcoma is rare. This article reports a case of diagnosis and treatment to enhance clinicians' understanding and experience in managing this disease. Methods: A 44-year-old patient with breast carcinosarcoma treated at the Breast Surgery Department of the First Hospital of Jilin University is reported, highlighting the challenges in the diagnostic process. Results: Postoperative pathology confirmed carcinosarcoma. The patient underwent mastectomy, chemotherapy, and radiotherapy, with no recurrence during follow-up. Conclusions: The nonspecific clinical manifestations of breast carcinosarcoma make preoperative diagnosis challenging, requiring a comprehensive diagnostic approach.
Keywords: breast cancer, Carcinosarcoma, Preoperative Diagnostic Challenges, Phyllodes Tumor, Metaplastic carcinoma
Received: 22 May 2025; Accepted: 10 Jul 2025.
Copyright: © 2025 Li, Bai, Ma, Fan, Wang and Qu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaozhen Wang, First Affiliated Hospital of Jilin University, Changchun, China
Fengjiang Qu, First Affiliated Hospital of Jilin University, Changchun, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.