SYSTEMATIC REVIEW article
Front. Med.
Sec. Rheumatology
Sleep disturbances and sleep quality among individuals diagnosed with osteoarthritis: A systematic review and meta-analysis
Provisionally accepted
Ansuman Panigrahi*
Priyanka Sahu
Swati Sambita Mohanty
Rutuparna Sibani DandsenaJewel Ipsita Sahani
Sanghamitra Pati- Regional Medical Research Center (ICMR), Bhubaneswar, India
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Introduction: Osteoarthritis is a leading cause of chronic pain and reduced mobility, especially in weight-bearing joints such as the knees and hips. While physical limitations associated with knee and/or hip osteoarthritis (KHOA) are well-documented, increasing attention is being paid to its impact on sleep disturbances and overall sleep quality. Understanding the extent and nature of these sleep-related issues is essential for the holistic management of knee and/or hip osteoarthritis. This study aims to synthesize current evidence on sleep disturbances and sleep quality in individuals diagnosed with knee and/or hip osteoarthritis. Methods: A systematic review and meta-analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Comprehensive searches were performed across multiple electronic databases, including Medline via PubMed, EMBASE, CINAHL via EBSCO, Scopus, Web of Science, and ScienceDirect. Additionally, grey literature was sourced through Google Scholar, ProQuest, and Sodhaganga. Studies focused on sleep quality, disturbances, and related factors among individuals with knee and/or hip osteoarthritis (KHOA) were screened. Finally, 17 articles were included in the final analysis. Results: Depression and elevated pain levels emerged as prominent contributors to sleep disturbances in individuals with KHOA. The meta-analysis revealed a pooled effect size of 8.53 (95% CI: 7.18–9.87) in Pittsburgh Sleep Quality Index (PSQI) scores, indicating significantly poorer sleep quality among patients with knee and/or hip osteoarthritis compared to healthy controls (p < 0.0001). However, there was substantial heterogeneity across studies (I² = 94.96%). Conclusion: This study highlights that individuals with knee and/or hip osteoarthritis experience significantly impaired sleep quality, primarily driven by pain and psychological factors. The findings underscore the need for integrated clinical approaches that address not only the physical symptoms of OA but also its broader impact on sleep and mental health.
Keywords: Sleep disturbances, sleep quality, Osteoarthritis knee, Osteoarthritis hip, Systematic review
Received: 30 Jun 2025; Accepted: 31 Oct 2025.
Copyright: © 2025 Panigrahi, Sahu, Mohanty, Dandsena, Sahani and Pati. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ansuman Panigrahi, dr.ansuman3@gmail.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.