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ORIGINAL RESEARCH article

Front. Med.

Sec. Hepatobiliary Diseases

Effects of phased focused nursing on liver function and self-care capacity in chronic hepatitis B patients

Provisionally accepted
Dongcang  HouDongcang Hou*Chunrong  PingChunrong PingWenying  HeWenying HeZeyang  ChenZeyang ChenGanlu  TianGanlu TianTian  QinTian QinWenjing  ZhouWenjing ZhouMenghui  XuMenghui XuXiaoman  RuanXiaoman Ruan
  • Second Hospital of Hebei Medical University, Shijiazhuang, China

The final, formatted version of the article will be published soon.

Aim: Chronic hepatitis B (CHB) patients often face challenges in liver function recovery, psychological well-being, and self-care ability during treatment. Conventional routine nursing may not comprehensively address these multi- dimensional issues. This study aimed to investigate the impacts of phased focused nursing on liver function and self-care ability in patients with CHB. Methods: A total of 120 CHB patients who received treatment in our hospital from March 2023 to March 2024 were selected and randomly divided into the control group and the study group. The control group received routine nursing, while the study group received phased focused nursing in addition to routine nursing. The liver function, psychological resilience, self-care ability, subjective well-being, quality of life, sleep quality, treatment compliance and nursing satisfaction were compared between the two groups before and after the intervention. Results: After the one-month intervention, the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and total bilirubin (TBil) were lower in the study group than those in the control group (P<0.01). After the one-month intervention, the scores of Connor-Davidson Resilience Scale (CD-RISC), Exercise of Self-care Agency Scale (ESCA) and World Health Organization Quality of Life-BREF Scale (WHOQOL-BREF) in the study group were higher than those in the control group (P<0.01). Compared with the control group, the study group had higher scores of positive emotions in Memorial University of Newfoundland Scale of Happiness (MUNSH) and lower scores of negative emotions in MUNSH after the one-month intervention (P<0.01). After the one-month intervention, the Pittsburgh Sleep Quality Index (PSQI) scores in the study group were lower than those in the control group (P<0.01). Compared with the control group, the treatment compliance and nursing satisfaction were higher in the study group (P<0.01 and P=0.01). Conclusion: Phased focused nursing can significantly improves liver function, has a more profound impact on enhancing psychological resilience, sleep quality, self-care capacity, subjective well-being, and quality of life. Additionally, it enhances treatment compliance and increases nursing satisfaction, indicating its superiority over routine nursing in the multi-dimensional management of CHB patients.  

Keywords: Chronic hepatitis B, phased focused nursing, Liver function, Self-care ability, treatment compliance

Received: 04 Aug 2025; Accepted: 28 Nov 2025.

Copyright: © 2025 Hou, Ping, He, Chen, Tian, Qin, Zhou, Xu and Ruan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dongcang Hou

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