The Evolution and Application of the Medical Evidence Chain

Yanan Bai¹Wanying Wang²jiajia Duan²Xue Wang²Mingjing Jiang³Han Ni³Lu Sun⁴Chuanxin Liu²Ding Li^5*

• ¹Xiamen University, Xiamen, China
• ²The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China
• ³Zhongyuan University of Technology, Zhengzhou, China
• ⁴Shanxi University of Chinese Medicine, Taiyuan, China
• ⁵Henan Provincial Cancer Hospital, Zhengzhou, China

Introduction Since the advent of evidence-based medicine, the decision-making process in disease diagnosis and treatment has exhibited fundamental principles that align closely with the core tenets of evidence chain theory in the legal field. Based on this, this paper aims to explore the underlying logic and practical value of transferring evidence chain theory from law to medicine, focusing on its significance in enhancing the scientific rigor and standardization of clinical decision-making. Methods Through systematic retrieval of existing literature in the fields of jurisprudence and medicine, this paper reviewed the theoretical evolution and practical applications of the evidence chain in jurisprudence, outlined the grading criteria for medical evidence, and elaborated on the construction methods and application examples of the integrated evidence chain and toxicological evidence chain. Results The mutual corroboration among evidence materials significantly enhances the reliability and validity of conclusions. The theory of evidence chains plays a pivotal role in evaluating drug efficacy, elucidating toxicological mechanisms, optimizing clinical pathways, and designing high-quality clinical trials. Conclusion The interdisciplinary application of the evidence chain theory contributes to advancing the standardization and normalization of evidence-based medical practice, thereby enhancing the quality of clinical decision-making and public health management.