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PERSPECTIVE article

Front. Med.

Sec. Precision Medicine

This article is part of the Research TopicExploring Precision Medicine in Reconstructive and Aesthetic SurgeryView all 8 articles

Precision and Safety Advantages of Ultrasound-Guided Nerve Blocks in Geriatric Anesthesia: Current Status and Future Prospects

Provisionally accepted
Xiao-yin  LinXiao-yin LinYa-mei  YangYa-mei YangYang  LiuYang LiuQing-qing  DangQing-qing DangKan  ZhangKan Zhang*
  • Yan’an People’s Hospital, Yan'an, China

The final, formatted version of the article will be published soon.

Ultrasound-guided regional anesthesia (UGRA) has emerged as a pivotal advancement in geriatric anesthesia, significantly enhancing procedural precision and patient safety through dynamic, real-time sonographic visualization. This technology overcomes critical limitations of conventional landmark-based techniques by enabling accurate needle navigation and localized anesthetic delivery, thereby improving block success rates while reducing volume requirements and systemic exposure. In elderly populations, characterized by heightened vulnerability to pharmacological adverse events and perioperative complications, UGRA facilitates opioid-minimized analgesia, attenuates neuroinflammatory responses, and lowers the incidence of delirium and cognitive dysfunction. Its alignment with Enhanced Recovery After Surgery (ERAS) protocols further promotes early mobilization and functional recovery. Despite existing challenges in technical training and resource allocation, ongoing innovations in imaging artificial intelligence, sustained-release local anesthetics, and personalized protocols hold substantial potential to broaden its applications. Future integration of UGRA into perioperative care necessitates standardized competency-based training and rigorously designed multicenter clinical trials to consolidate its role in improving outcomes for the aging surgical population.

Keywords: Ultrasound-guided regional anesthesia, Nerve Block, Geriatric anesthesia, postoperative cognitive dysfunction, Enhanced recovery after surgery, Precision, Safety

Received: 20 Sep 2025; Accepted: 03 Nov 2025.

Copyright: © 2025 Lin, Yang, Liu, Dang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Kan Zhang

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