CASE REPORT article
Front. Med.
Sec. Pathology
Case Report: Pathological Confirmation and Aggressive Postoperative Recurrence of WHO Grade III Rhabdoid Meningioma
Provisionally accepted
- 1Sixth People's Hospital of Chengdu, Chengdu, China
- 2The Second Affiliated Hospital of Kunming Medical University, Kunming, China
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Rhabdoid meningioma (RM), a rare WHO grade III meningioma subtype, features high invasiveness, poor prognosis, and no effective therapies, often being misdiagnosed with other intracranial tumors clinically, such as brain metastases and WHO grade II meningiomas. We report a 39-year-old female admitted for 6-month headaches. Brain magnetic resonance imaging (MRI) showed a well-circumscribed, heterogeneously enhancing tumor with severe peritumoral edema in the right temporal lobe, initially suspected to be a WHO grade II meningioma; RM was confirmed postoperatively. The tumor recurred one month after the first surgery, and the patient died of intracranial hypertension one month after the reoperation. This case highlights the need for immediate adjuvant chemoradiotherapy postoperatively.
Keywords: case report, chemotherapy, Postoperative recurrence, Radiotherapy, Rhabdoid meningioma
Received: 29 Sep 2025; Accepted: 01 Dec 2025.
Copyright: © 2025 Xu, Wang, wang, Lian, Gao, Guo, Qiao and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Rui Xu
Yongjun Gao
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