CASE REPORT article
Front. Med.
Sec. Gastroenterology
Diffuse large B-cell lymphoma with intussusception in adults:A Case Report and Literature Review
Provisionally accepted
- 1Department of Emergency Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China
- 2Department of Clinical Laboratory, First Affiliated Hospital of Gannan Medical University, Ganzhou, China
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Intussusception secondary to gastrointestinal diffuse large B-cell lymphoma (DLBCL) is exceedingly rare in adults. We present a case of a 23-year-old male admitted with abdominal pain as the primary symptom. Computed tomography (CT) revealed an ileocolic intussusception involving the ascending and transverse colon, demonstrating a characteristic "target". Conservative treatment (including air enema) was ineffective, and the patient finally received surgical treatment. The resected lesion was pathologically confirmed as DLBCL. The patient received postoperative chemotherapy with the R-CHOP regimen. At the 5-month follow-up, no complications or evidence of lymph node involvement elsewhere was observed. Adult intussusception patients should be highly alert to the possibility of malignant tumors, especially lymphoma. Early diagnosis and standardized comprehensive treatment are critical for improving long-term prognosis.
Keywords: Intussusception, B cell lymphoma, Diffuse large B-cell lymphoma, non-Hodgkin 's lymphoma, Gastrointestinal lymphoma, case report
Received: 03 Oct 2025; Accepted: 03 Dec 2025.
Copyright: © 2025 He, Cai, Xie, Pan, Liu and Lin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xuan Lin
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