ORIGINAL RESEARCH article

Front. Med.

Sec. Nephrology

Optimized Urological Diagnostics based on Kidney Stone Detection in Clinical CT Imaging Using YOLOv8 Deep Learning Approach

  • 1. University of Saskatchewan, Saskatoon, Canada

  • 2. Zhejiang Provincial People's Hospital Urology and Nephrology Center, Hangzhou, China

The final, formatted version of the article will be published soon.

Abstract

Kidney stone disease poses a growing global health challenge due to its increasing prevalence and potential for serious complications if left undiagnosed or untreated. Non-contrast computed tomography (CT) remains the gold standard for detecting renal calculi; however, the manual review of CT scans is time-consuming and prone to variability among radiologists. This study introduces the application of deep learning-based object detection model for automated kidney stone detection in abdominal CT images. Four state-of-the-art models, YOLOv8, YOLOv5, Faster R-CNN, and RetinaNet, were evaluated on a curated dataset of 4,000 annotated CT slices from both pre-and postsurgical patient groups. Performance metrics including mean Average Precision (mAP@0.5), precision, recall, false positive/negative rates, and inference speed were analyzed. YOLOv8 achieved a compelling balance between accuracy (mAP@0.91) and real-time inference capability (65 FPS), making it the most practical for clinical integration. While Faster R-CNN demonstrated superior localization accuracy (mAP@0.93), its slower inference speed limits its utility in time-sensitive environments. These findings highlight the potential of single-stage detectors, particularly YOLOv8, for enhancing diagnostic efficiency and consistency in urological imaging workflows.

Summary

Keywords

Clinical decision support, Kidney Stones, Medical Image Analysis, object detection, Real-time detection, YOLOv8

Received

09 September 2025

Accepted

17 February 2026

Copyright

© 2026 Chipusu, He and Shen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Liuying He

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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