SYSTEMATIC REVIEW article
Front. Med.
Sec. Pulmonary Medicine
Efficacy and Safety of Supraglottic Jet Oxygenation and Ventilation in Chinese Patients Undergoing Bronchoscopic Procedures: A Systematic Review and Meta-Analysis
Mingyuan Yang
Hong Li
Qinghao Cheng
Emergency General Hospital, Beijing, China
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Abstract
Purpose Hypoxemia remains a major complication during bronchoscopic procedures. This systematic review and meta-analysis is to systematically evaluate the efficacy and safety of Supraglottic jet oxygenation and ventilation (SJOV) in preventing hypoxemia and improving clinical outcomes during bronchoscopy procedures. Methods Databases including Embase, MEDLINE, PubMed, Cochrane Library, Weipu, SinoMed, Wanfang Data and China National Knowledge Infrastructure were searched for randomized studies comparing SJOV with other conventional oxygen therapy in adult patients undergoing diagnostic or therapeutic bronchoscopy. The primary outcome was the incidence of hypoxic events. Secondary outcomes included the need for airway assistance, arteria blood gas, peri-operative adverse events. Results A total of 1090 records were screened, and 10 RCTs involving 1109 patients (555 in the SJOV group, 554 in the control group) were included, all conducted in China. SJOV significantly reduced the incidence of hypoxemia (OR=0.20, 95%CI [0.07–0.58], I²=80%), improved mean intraoperative oxygen saturation (SpO₂) (2.27, [0.12–4.42], 99%) and arterial oxygen partial pressure (PaO₂) compared with control group (36.31, [6.16– 66.46], 99%). SJOV substantially reduced the need for jaw lift (0.09, [0.03–0.30], 79%), adjustment of ventilator parameters (0.05, [0.03–0.12], 45%), and mask ventilation with positive pressure (0.04, [0.01–0.12], 0%). SJOV was associated with a higher incidence of post-procedural xerostomia (6.08, [2.99–12.36], 44%) and sore throat (1.71, [1.08–2.71], 0.00), but no significant difference in nasal bleeding (0.70, [0.39–1.25], 0%). Intraoperatively, SJOV showed lower tachycardia (0.35, [0.14–0.91],15%) and reduced hypertension incidence (OR=0.20, [0.06–0.70], 45%). Conclusion SJOV significantly improves oxygenation, reduces hypoxemia and rescue interventions during bronchoscopy, with a manageable safety profile. It may be a valuable oxygenation strategy for bronchoscopic procedures, especially in high-risk patients.
Summary
Keywords
Bronchoscopy, hypoxemia, Meta-analysis, Supraglottic jet oxygenation and ventilation, Systematic review
Received
09 October 2025
Accepted
09 February 2026
Copyright
© 2026 Yang, Li and Cheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Mingyuan Yang; Qinghao Cheng
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