Your new experience awaits. Try the new design now and help us make it even better

REVIEW article

Front. Med.

Sec. Gastroenterology

The Evolving Role of Endoscopic Ultrasound from Diagnosis to Therapy in Hepatic Vascular Interventions

Provisionally accepted
Shixue  XuShixue XuJitong  JiangJitong JiangJintao  GuoJintao GuoSheng  WangSheng WangNan  GeNan GeRongmin  XuRongmin XuFan  YangFan Yang*
  • Department of Gastroenterology, Shengjing Hospital of China Medical University, shenyang, China

The final, formatted version of the article will be published soon.

Endohepatology, the integration of advanced endoscopy into hepatology, is rapidly evolving beyond standard diagnostics. This review focuses on its burgeoning vascular applications, particularly through Endoscopic Ultrasound (EUS). EUS-guided portal pressure gradient measurement (EUS-PPG) is establishing a new paradigm for direct portal hypertension assessment. Therapeutically, EUS enables precise vascular interventions such as coil and glue embolization for gastric varices and spontaneous portosystemic shunts, moving beyond blind techniques. Pioneering, bench-to-bedside procedures like the creation of EUS-guided intrahepatic portosystemic shunts (EUS-IPS) represent the next frontier. While technical complexity remains, EUS is a transformative platform within endohepatology. This article explores these cutting-edge applications and prognosticates future techniques set to redefine the management of complex hepatobiliary and vascular diseases.

Keywords: Endohepatology, endoscopic ultrasound, Liver Cirrhosis, portal hypertension, Vascular intervention

Received: 09 Nov 2025; Accepted: 16 Feb 2026.

Copyright: © 2026 Xu, Jiang, Guo, Wang, Ge, Xu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Fan Yang

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.