REVIEW article
Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
This article is part of the Research TopicAdvances in Critical Care Blood PurificationView all 5 articles
Summary of Best Evidence for Nutritional Management in Adult Patients Undergoing Continuous Renal Replacement Therapy
Provisionally accepted
- Third Hospital of Hebei Medical University, Shijiazhuang, China
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Objective To retrieve, screen, appraise, and synthesize the best evidence on nutritional management for adult patients undergoing continuous renal replacement therapy (CRRT) to inform the development of standardized clinical nutrition management protocols for CRRT. Methods Using the 5S evidence pyramid model, we conducted a top-down search of domestic and international sources, including databases of systematic reviews, guideline portals, professional association websites, and comprehensive databases, to identify clinical decision aids, evidence summaries, guidelines, standards, protocols, systematic reviews, and expert consensus statements. The search period was from January 1, 2006, to December 31, 2025. Two evidence-based nursing experts independently performed quality appraisal, evidence extraction, and grading for the included literature. Results: A total of 12 documents were included: 1 clinical decision aid, 1 evidence summary, 8 guidelines, and 2 expert consensus statements. After systematic extraction and integration of the relevant evidence, 16 evidence points were summarized across three domains: nutritional assessment and selection of nutritional pathways, energy and protein provision, and monitoring and supplementation of electrolytes and micronutrients. Conclusion: The best available evidence on nutritional management for adults undergoing CRRT synthesized in this study is comprehensive and scientifically sound. It provides a reference for clinical practice. However, personalized nutritional plans should be developed based on patients' clinical conditions to improve outcomes.
Keywords: Blood purification, continuous renal replacement therapy, evidence summary, Evidence-basednursing, nutrition
Received: 19 Nov 2025; Accepted: 20 Jan 2026.
Copyright: © 2026 Jia, Wei, Zhu, Wang and Sun. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
LiWei Jia
Xue Wang
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