CASE REPORT article
Front. Med.
Sec. Hematology
Case report: A case of solitary bone plasmacytoma to multiple myeloma
Ni Fu 1
Zhimin Fang 2
Zhong Tian 1
Jiyang Tang 2
Bo Lei 2
Zhongcong He 1
Cheng Zhu 1
Huangyu Luo 1
Yuguang Shen 2
1. Department of Urology, Second Affiliated Hospital of Zunyi Medical University, Zunyi, China
2. The First People's Hospital of Zunyi, Zunyi, China
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Abstract
Solitary bone plasmacytoma of the rib is uncommon but recognized. We report a case presenting with recurrent, predominantly nocturnal chest wall pain. Imaging revealed an expansile lesion of the left ninth rib and initially suggested fibrous/osteofibrous dysplasia. The patient underwent resection of the involved rib segment. Histopathology and immunohistochemistry confirmed solitary bone plasmacytoma. The patient declined recommended adjuvant radiotherapy. Twenty-one months later, the disease progressed to multiple myeloma.
Summary
Keywords
mm, Rib, SBP, SEP, SP
Received
23 December 2025
Accepted
09 February 2026
Copyright
© 2026 Fu, Fang, Tian, Tang, Lei, He, Zhu, Luo and Shen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Ni Fu; Yuguang Shen
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