MINI REVIEW article
Front. Med.
Sec. Gastroenterology
Peristomal Pyoderma Gangrenosum: A Review of Nursing Research Progress
Guowei Chen 1
Xiaoxu Lan 1
Fang Li 1
Deyuan Zeng 1
Luhong Wang 1
Xiaoyu Chen 2
Li Zhu 1
1. Chongqing General Hospital, Chongqing, China
2. Xipeng Health Center, Chongqing, China
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Abstract
Peristomal Pyoderma Gangrenosum (PPG) is a rare and therapeutically challenging inflammatory dermatosis predominantly affecting individuals with stoma surgery. This review provides a comprehensive overview of PPG, encompassing its etiology, clinical manifestations, diagnostic methods, treatment strategies, and nursing management. PPG's multifactorial etiology involves immune dysfunction, genetic predisposition, surgical trauma, and demographic factors, which contribute to the formation of painful ulcers that significantly impair patients' quality of life. Accurate diagnosis requires a multidisciplinary approach, including clinical evaluation, 2 histopathological examination, and advanced diagnostic criteria.Effective management combines local wound care, systemic therapies, and surgical interventions, emphasizing a patient-centered and evidence-based approach. Nursing strategies, including advanced wound care, pain management, psychological support, nutritional interventions, and health education, play a vital role in optimizing outcomes and preventing recurrence. Future research should focus on the development of specific biomarkers, novel therapeutic agents, and standardized nursing protocols to address the unmet needs in PPG care. This integrated diagnostic, therapeutic, and nursing framework aims to enhance patient outcomes and provide insights for future clinical and research advancements.
Summary
Keywords
Immunosuppressive treatment, Negative pressure wound therapy, Ostomy complications, Peristomal pyoderma gangrenosum, wound nursing
Received
24 December 2025
Accepted
18 February 2026
Copyright
© 2026 Chen, Lan, Li, Zeng, Wang, Chen and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Guowei Chen; Li Zhu
Disclaimer
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