Frontiers in Medicine | Precision Medicine

Original Research

Published on 22 Jun 2021

Long Non-coding RNA SNHG12, a New Therapeutic Target, Regulates miR-199a-5p/Klotho to Promote the Growth and Metastasis of Intrahepatic Cholangiocarcinoma Cells

in Precision Medicine

Hong-Guo Yang
Tian-peng Wang
Sheng-an Hu
Chao-zhou Hu
Cheng-hang Jiang
Qiang He

Frontiers in Medicine

doi 10.3389/fmed.2021.680378

3,817 views
7 citations

Original Research

Published on 31 May 2021

Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2

in Precision Medicine

Vijay Kumar Bhardwaj
Rahul Singh
Jatin Sharma
Vidya Rajendran
Rituraj Purohit
Sanjay Kumar

Frontiers in Medicine

doi 10.3389/fmed.2021.684020

7,027 views
56 citations

Original Research

Published on 26 May 2021

MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy

in Precision Medicine

Xing Niu
Biying Huang
Xue Qiao
Jinwen Liu
Lijie Chen
Ming Zhong

Frontiers in Medicine

doi 10.3389/fmed.2021.670188

3,630 views
21 citations

Original Research

Published on 24 May 2021

Potential Prognostic Immune Biomarkers of Overall Survival in Ovarian Cancer Through Comprehensive Bioinformatics Analysis: A Novel Artificial Intelligence Survival Prediction System

in Precision Medicine

Tingshan He
Liwen Huang
Jing Li
Peng Wang
Zhiqiao Zhang

Frontiers in Medicine

doi 10.3389/fmed.2021.587496

6,254 views
12 citations

Original Research

Published on 24 May 2021

Exosomal Circular RNA RNA-seq Profiling and the Carcinogenic Role of Exosomal circ-CYP24A1 in Cutaneous Squamous Cell Carcinoma

in Precision Medicine

Zheng Zhang
Hao Guo
Wenjia Yang
Jiuhong Li

Frontiers in Medicine

doi 10.3389/fmed.2021.675842

5,224 views
21 citations

Original Research

Published on 24 May 2021

Multi-Omics Integrative Analysis Uncovers Molecular Subtypes and mRNAs as Therapeutic Targets for Liver Cancer

in Precision Medicine

Yi Shen
Wei Xiong
Qi Gu
Qin Zhang
Jia Yue
Changsong Liu
Duan Wang

Frontiers in Medicine

doi 10.3389/fmed.2021.654635

5,641 views
4 citations

Original Research

Published on 24 May 2021

Long Non-coding RNA EBLN3P Regulates UHMK1 Expression by Sponging miR-323a-3p and Promotes Colorectal Cancer Progression

in Precision Medicine

Xiang-hao Xu
Wen Song
Jun-hua Li
Ze-qi Huang
Ya-fang Liu
Qiang Bao
Zhi-wen Shen

Frontiers in Medicine

doi 10.3389/fmed.2021.651600

4,194 views
33 citations

Opinion

Published on 14 May 2021

Limitations of Only Reporting the Odds Ratio in the Age of Precision Medicine: A Deterministic Simulation Study

in Precision Medicine

Avishek Chatterjee
Henry Woodruff
Guangyao Wu
Philippe Lambin

Frontiers in Medicine

doi 10.3389/fmed.2021.640854

4,742 views
7 citations

Original Research

Published on 12 May 2021

LncRNA PITPNA-AS1 as a Potential Diagnostic Marker and Therapeutic Target Promotes Hepatocellular Carcinoma Progression via Modulating miR-448/ROCK1 Axis

in Precision Medicine

Qing-fang Wang
Qing-lin Wang
Ming-bo Cao

Frontiers in Medicine

doi 10.3389/fmed.2021.668787

3,291 views
14 citations

Original Research

Published on 07 May 2021

Phytochemical Moieties From Indian Traditional Medicine for Targeting Dual Hotspots on SARS-CoV-2 Spike Protein: An Integrative in-silico Approach

in Precision Medicine

V. Umashankar
Sanjay H. Deshpande
Harsha V. Hegde
Ishwar Singh
Debprasad Chattopadhyay

Frontiers in Medicine

doi 10.3389/fmed.2021.672629

11,842 views
55 citations

Original Research

Published on 27 Apr 2021

hsa-miR-33-5p as a Therapeutic Target Promotes Apoptosis of Breast Cancer Cells via Selenoprotein T

in Precision Medicine

Wei Zhuang
Jianhui Liu
Wenjin Li

Frontiers in Medicine

doi 10.3389/fmed.2021.651473

3,331 views
7 citations

Original Research

Published on 22 Apr 2021

Long Non-coding RNA LINC00847 Induced by E2F1 Accelerates Non-small Cell Lung Cancer Progression Through Targeting miR-147a/IFITM1 Axis

in Precision Medicine

Huan Li
Yao-kai Chen
Qiu Wan
An-qi Shi
Min Wang
Ping He
Li-xin Tang

Frontiers in Medicine

doi 10.3389/fmed.2021.663558

3,675 views
28 citations

Original Research

Published on 13 Apr 2021

A Ferroptosis-Related Signature Robustly Predicts Clinical Outcomes and Associates With Immune Microenvironment for Thyroid Cancer

in Precision Medicine

Mingqin Ge
Jie Niu
Ping Hu
Aihua Tong
Yan Dai
Fangjiang Xu
Fuyuan Li

Frontiers in Medicine

doi 10.3389/fmed.2021.637743

6,186 views
19 citations

Original Research

Published on 13 Apr 2021

Computational Simulation of Exosome Transport in Tumor Microenvironment

in Precision Medicine

Roy Koomullil
Behnam Tehrani
Kayla Goliwas
Yong Wang
Selvarangan Ponnazhagan
Joel Berry
Jessy Deshane

Frontiers in Medicine

doi 10.3389/fmed.2021.643793

7,173 views
20 citations

Original Research

Published on 13 Apr 2021

Targeting Antisense lncRNA PRKAG2-AS1, as a Therapeutic Target, Suppresses Malignant Behaviors of Hepatocellular Carcinoma Cells

in Precision Medicine

Yanjiao Ou
Yong Deng
Hong Wang
Qingyi Zhang
Huan Luo
Peng Hu

Frontiers in Medicine

doi 10.3389/fmed.2021.649279

4,338 views
9 citations

Original Research

Published on 01 Apr 2021

Three Immune-Related Prognostic mRNAs as Therapeutic Targets for Pancreatic Cancer

in Precision Medicine

Cangang Zhang
Yueji Zou
Yanan Zhu
Yi Liu
Hui Feng
Fan Niu
Pengcheng He
Haibo Liu

Frontiers in Medicine

doi 10.3389/fmed.2021.649326

6,312 views
17 citations

Original Research

Published on 31 Mar 2021

Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients

in Precision Medicine

Chun-hui Zheng
Zhao-yun Liu
Chen-xi Yuan
Xiao-yun Dong
Hai-mei Li
Jin-jin Wang
Zhao-peng Zhang
Hong-Ying Liu
Xiao-yan Ding
Wendy Wu

Frontiers in Medicine

doi 10.3389/fmed.2021.651904

4,028 views
13 citations

Hypothesis and Theory

Published on 22 Mar 2021

Sudden Cardiac Death—A New Insight Into Potentially Fatal Genetic Markers

in Precision Medicine

Dragan Primorac
Ljubica Odak
Vitorio Perić
Jasmina Ćatić
Jozica Šikić
Vjekoslav Radeljić
Šime Manola
Robert Nussbaum
Matteo Vatta
Swaroop Aradhya

Frontiers in Medicine

doi 10.3389/fmed.2021.647412

15,951 views
10 citations

Review

Published on 18 Mar 2021

Diagnostic and Prognostic Value of Circulating CircRNAs in Cancer

in Precision Medicine

Mina Wang
Feiyu Xie
Jiaran Lin
Yihan Zhao
Qian Zhang
Zehuan Liao
Peng Wei

Frontiers in Medicine

doi 10.3389/fmed.2021.649383

8,417 views
46 citations

Original Research

Published on 18 Mar 2021

Correlation Between Pulmonary Sclerosing Pneumocytoma Features and MSCT Imaging Manifestations in 34 Patients: Implications for Precision Medicine

in Precision Medicine

Gen Xu
Zhaoyu Wang
Zeng Xiong
Manqiu Li
Weijun Luo
Yong Xu
Tang Min

Frontiers in Medicine

doi 10.3389/fmed.2021.650996

3,431 views
9 citations

Original Research

Published on 05 Mar 2021

Comprehensive Analysis Identifies Potential Ferroptosis-Associated mRNA Therapeutic Targets in Ovarian Cancer

in Precision Medicine

Jiyan Zhang
Jie Xi
Ping Huang
Saitian Zeng

Frontiers in Medicine

doi 10.3389/fmed.2021.644053

9,106 views
27 citations

Original Research

Published on 05 Mar 2021

C3AR1 mRNA as a Potential Therapeutic Target Associates With Clinical Outcomes and Tumor Microenvironment in Osteosarcoma

in Precision Medicine

Tiannan Zou
Weibing Liu
Zeyu Wang
Jiayu Chen
Sheng Lu
Kun Huang
Weichao Li

Frontiers in Medicine

doi 10.3389/fmed.2021.642615

6,163 views
14 citations

Review

Published on 03 Mar 2021

CRISPR/Cas: Advances, Limitations, and Applications for Precision Cancer Research

in Precision Medicine

Yue Yang
Jin Xu
Shuyu Ge
Liqin Lai

Frontiers in Medicine

doi 10.3389/fmed.2021.649896

93,123 views
129 citations

Original Research

Published on 19 Feb 2021

Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways

in Precision Medicine

Mingyan Yao
Jing Zhang
Zhihong Li
Xiaoliang Bai
Jinhui Ma
Yukun Li

Frontiers in Medicine

doi 10.3389/fmed.2021.630962

6,527 views
36 citations

800 articles

articles

Long Non-coding RNA SNHG12, a New Therapeutic Target, Regulates miR-199a-5p/Klotho to Promote the Growth and Metastasis of Intrahepatic Cholangiocarcinoma Cells

Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2

MicroRNA-1-3p Suppresses Malignant Phenotypes of Ameloblastoma Through Down-Regulating Lysosomal Associated Membrane Protein 2-Mediated Autophagy

Potential Prognostic Immune Biomarkers of Overall Survival in Ovarian Cancer Through Comprehensive Bioinformatics Analysis: A Novel Artificial Intelligence Survival Prediction System

Exosomal Circular RNA RNA-seq Profiling and the Carcinogenic Role of Exosomal circ-CYP24A1 in Cutaneous Squamous Cell Carcinoma

Multi-Omics Integrative Analysis Uncovers Molecular Subtypes and mRNAs as Therapeutic Targets for Liver Cancer

Long Non-coding RNA EBLN3P Regulates UHMK1 Expression by Sponging miR-323a-3p and Promotes Colorectal Cancer Progression

Limitations of Only Reporting the Odds Ratio in the Age of Precision Medicine: A Deterministic Simulation Study

LncRNA PITPNA-AS1 as a Potential Diagnostic Marker and Therapeutic Target Promotes Hepatocellular Carcinoma Progression via Modulating miR-448/ROCK1 Axis

Phytochemical Moieties From Indian Traditional Medicine for Targeting Dual Hotspots on SARS-CoV-2 Spike Protein: An Integrative in-silico Approach

hsa-miR-33-5p as a Therapeutic Target Promotes Apoptosis of Breast Cancer Cells via Selenoprotein T

Long Non-coding RNA LINC00847 Induced by E2F1 Accelerates Non-small Cell Lung Cancer Progression Through Targeting miR-147a/IFITM1 Axis

A Ferroptosis-Related Signature Robustly Predicts Clinical Outcomes and Associates With Immune Microenvironment for Thyroid Cancer

Computational Simulation of Exosome Transport in Tumor Microenvironment

Targeting Antisense lncRNA PRKAG2-AS1, as a Therapeutic Target, Suppresses Malignant Behaviors of Hepatocellular Carcinoma Cells

Three Immune-Related Prognostic mRNAs as Therapeutic Targets for Pancreatic Cancer

Mutant Allele Frequency-Based Intra-Tumoral Genetic Heterogeneity Related to the Tumor Shrinkage Mode After Neoadjuvant Chemotherapy in Breast Cancer Patients

Sudden Cardiac Death—A New Insight Into Potentially Fatal Genetic Markers

Diagnostic and Prognostic Value of Circulating CircRNAs in Cancer

Correlation Between Pulmonary Sclerosing Pneumocytoma Features and MSCT Imaging Manifestations in 34 Patients: Implications for Precision Medicine

Comprehensive Analysis Identifies Potential Ferroptosis-Associated mRNA Therapeutic Targets in Ovarian Cancer

C3AR1 mRNA as a Potential Therapeutic Target Associates With Clinical Outcomes and Tumor Microenvironment in Osteosarcoma

CRISPR/Cas: Advances, Limitations, and Applications for Precision Cancer Research

Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways