REVIEW article
Front. Mol. Biosci.
Sec. Micronutrient Biology
Volume 12 - 2025 | doi: 10.3389/fmolb.2025.1623547
This article is part of the Research TopicThe Role of Micronutrients on Brain FunctionView all 3 articles
Unveiling the Mechanistic Nexus: How Micronutrient Enrichment Shapes Brain Function, and Cognitive Health
Provisionally accepted
- 1Department of Plant Pathology, M.S. Swaminathan School of Agriculture, Centurion University of Technology and Management, Odisha, India, Paralakhemundi, India
- 2McGowan Institute for regenerative Medicine, Department of Surgery, University of Pittsburgh, 450 Technology, Dr, Pittsburgh, PA, USA, Pittsburgh, United States
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Minerals, vitamins, and trace elements are examples of micronutrients essential for psychological well-being and brain function. Severe disorders may result from their deficiency or, conversely, from an excess of them. Recent studies have indicated that the etiopathogenesis of certain neurological disorders may involve chronically elevated micronutrient levels.Physiological functions, such as energy metabolism, neurotransmitter synthesis, and antioxidant defence, are regulated by these vital nutrients and are essential for optimal neuronal activity.According to new research, micronutrient enrichment, whether through diet or supplements, can have a significant impact on cognitive function, neuroplasticity, and brain development.Cognitive decline, memory loss, and attention problems are linked to deficiencies in essential micronutrients, including vitamin B12, iron, zinc, and omega-3 fatty acids. Tailored micronutrient therapies have shown promise in reducing age-related cognitive decline and enhancing mental function in both healthy individuals and those at greater risk. This manuscript emphasizes the growing research linking micronutrient status to cognitive health. It also highlights the importance of maintaining a balanced diet and following appropriate supplementation practices to optimize brain function throughout life.
Keywords: cognitive decline, Brain Development, neuroplasticity, epigenetics, Mental Health
Received: 06 May 2025; Accepted: 29 Aug 2025.
Copyright: © 2025 Das, Banerjee, Jana and Mondal. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Siddhartha Das, Department of Plant Pathology, M.S. Swaminathan School of Agriculture, Centurion University of Technology and Management, Odisha, India, Paralakhemundi, India
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