ORIGINAL RESEARCH article
Front. Mol. Biosci.
Sec. Molecular Diagnostics and Therapeutics
Volume 12 - 2025 | doi: 10.3389/fmolb.2025.1660379
This article is part of the Research TopicAdvancing Biomarker Discovery, Molecular Mechanisms, and Immunological Insights in Tumor Precision MedicineView all 5 articles
The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma
Provisionally accepted
- 1Department of Medical Oncology, Brunch of Minhang, Fudan University Shanghai Cancer Hospital, Shanghai, China
- 2Department of Pathology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China
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Purpose ： This study examined the associations between composite inflammatory indicators-including the Monocyte-to-Lymphocyte Ratio (MLR), Systemic Inflammation Response Index (SIRI), and Systemic Immune-Inflammation Index (SII)-and the clinicopathological characteristics in patients with Differentiated Thyroid Carcinoma (DTC). To provide a novel insight into refining patient selection criteria for active surveillance (AS) strategies in DTC patients.Methods：This retrospective study analyzed preoperative MLR, SIRI, and SII values in 231 DTC patients treated at
Keywords: Differentiated thyroid carcinoma, Clinicopathological characteristics, Monocyte-to-lymphocyte ratio, systemic inflammation response index, systemic immune-inflammation index
Received: 05 Jul 2025; Accepted: 12 Aug 2025.
Copyright: © 2025 Li Yuan and Li Peng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yang Li Peng, Department of Pathology, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China
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