Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Review

Published on 09 Feb 2023

Companion diagnostic requirements for spatial biology using multiplex immunofluorescence and multispectral imaging

in Molecular Diagnostics and Therapeutics

Darren Locke
Clifford C. Hoyt

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1051491

15,843 views
22 citations

Original Research

Published on 09 Feb 2023

Identification of AKR1B10 as a key gene in primary biliary cholangitis by integrated bioinformatics analysis and experimental validation

in Molecular Diagnostics and Therapeutics

Huiwen Wang
Jian Zhang
Jinqing Liu
Yongfang Jiang
Lei Fu
Shifang Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1124956

4,962 views
1 citation

Original Research

Published on 07 Feb 2023

Pan-cancer integrated bioinformatics analysis reveals cuproptosis related gene FDX1 is a potential prognostic and immunotherapeutic biomarker for lower-grade gliomas

in Molecular Diagnostics and Therapeutics

Wei Huang
Yuliang Wu
Jihui Zhu
Ning Luo
Chunyan Wang
Shupeng Liu
Zhongping Cheng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.963639

8,583 views
8 citations

Original Research

Published on 07 Feb 2023

Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project

in Molecular Diagnostics and Therapeutics

Ana Peixoto
Luís Cirnes
Ana Luísa Carvalho
Maria João Andrade
Maria José Brito
Paula Borralho
Nuno Coimbra
Pedro M. Borralho
Ana Sofia Carneiro
Lisandra Castro

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1082915

5,978 views
5 citations

Review

Published on 07 Feb 2023

Role of LGMN in tumor development and its progression and connection with the tumor microenvironment

in Molecular Diagnostics and Therapeutics

Safir Ullah Khan
Ibrar Muhammad Khan
Munir Ullah Khan
Muhammad Azhar Ud Din
Muhammad Zahoor Khan
Nazir Muhammad Khan
Yong Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1121964

8,336 views
29 citations

Editorial

Published on 03 Feb 2023

Editorial: Synthetic biology in Vertebrate Model system: New clinical and preclinical translational applications

in Molecular Diagnostics and Therapeutics

Xu Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1117896

1,083 views

Review

Published on 03 Feb 2023

Molecular classification and therapeutics in diffuse large B-cell lymphoma

in Molecular Diagnostics and Therapeutics

Gaelen Shimkus
Taichiro Nonaka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1124360

12,942 views
8 citations

Mini Review

Published on 03 Feb 2023

Specialized pro-resolving lipid mediators regulate inflammatory macrophages: A paradigm shift from antibiotics to immunotherapy for mitigating COVID-19 pandemic

in Molecular Diagnostics and Therapeutics

Vikram Kumar
Nusrath Yasmeen
Anis Ahmad Chaudhary
Abdullah S. Alawam
Mohammed Al-Zharani
Nosiba Suliman Basher
S. Harikrishnan
Muddapuram Deeksha Goud
Aishwarya Pandey
Sudarshan Singh Lakhawat

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1104577

7,439 views
13 citations

Editorial

Published on 02 Feb 2023

Editorial: Small molecule inhibitors targeting mammalian selenoprotein thioredoxin reductases (TXNRDs): Interactions, mechanisms, and applications

in Molecular Diagnostics and Therapeutics

Jianqiang Xu
Alexios Vlamis-Gardikas
Jianguo Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1141772

1,738 views

Original Research

Published on 02 Feb 2023

Role of immediate early genes in the development of salivary gland organoids in polyisocyanopeptide hydrogels

in Molecular Diagnostics and Therapeutics

Paulien Schaafsma
Laura Kracht
Mirjam Baanstra
Anne L. Jellema-de Bruin
Robert P. Coppes

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1100541

4,980 views
10 citations

Original Research

Published on 30 Jan 2023

Rhodobacter sphaeroides as a model to study the ecotoxicity of 1-alkyl-3-methylimidazolium bromide

in Molecular Diagnostics and Therapeutics

Xiao-Lin Liu
Ming-Qing Chen
Yang-Lin Jiang
Rong-Yao Gao
Ze-Jun Wang
Peng Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1106832

2,296 views
3 citations

Brief Research Report

Published on 30 Jan 2023

New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

in Molecular Diagnostics and Therapeutics

Monica Hepker
Griffin Clabaugh
Huajun Jin
Anumantha G. Kanthasamy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1087982

3,011 views
4 citations

Editorial

Published on 25 Jan 2023

Editorial: Exploring circular RNAs and their applications within health and disease

in Molecular Diagnostics and Therapeutics

Matteo Becatti
Crismita Dmello
Binod Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1145738

2,076 views
1 citation

Original Research

Published on 23 Jan 2023

In silico prediction of molecular mechanisms of toxicity mediated by the leptospiral PF07598 gene family-encoded virulence-modifying proteins

in Molecular Diagnostics and Therapeutics

Reetika Chaurasia
Joseph M. Vinetz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2022.1092197

5,194 views
7 citations

Original Research

Published on 23 Jan 2023

Unraveling the impact of a germline heterozygous POLD1 frameshift variant in serrated polyposis syndrome

in Molecular Diagnostics and Therapeutics

Laia Bonjoch
Yasmin Soares de Lima
Marcos Díaz-Gay
Isabella Dotti
Jenifer Muñoz
Leticia Moreira
Sabela Carballal
Teresa Ocaña
Miriam Cuatrecasas
Oswaldo Ortiz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1119900

5,001 views
2 citations

Original Research

Published on 19 Jan 2023

Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model

in Molecular Diagnostics and Therapeutics

Xuewen Song
Wouter N. Leonhard
Anish A. Kanhai
Gregory R. Steinberg
York Pei
Dorien J. M. Peters

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1058825

6,109 views
5 citations