In the original article, there was a mistake in Figure 4 as published. Panels A, B, C, D, E, F of the published Figure 4 were incorrectly labeled. The corrected Figure 4 appears below.
Figure 4
Hyper-phosphorylated tau-containing cells and threads following unilateral intra-hippocampal injection of sarkosyl-insoluble fractions from PART into WT mice at the age of 7 months and killed at the age of 10 months (3 months survival) (A,C); 3 months and killed at the age of 10 months (C,D–F); and at the age of 12 months and killed at the age of 19 months (7 months survival) (G–J). Tau deposits in neurons, independently of the survival time, show granular deposits in the cytoplasm, and occasional denser inclusions with no similarities with tangles (A,B). Threads and coiled bodies are abundant in the fimbria and corpus callosum (C–F). Individual neurons, threads and oligodendrocytes in inoculated mice are stained with anti-4Rtau (G,H) and anti-3Rtau (I,J) antibodies. Paraffin sections slightly counterstained with hematoxylin. CA1, region of the hippocampus; fimbr, fimbria; ipsi contr CC, ipsi- and contralateral corpus callosum; (A–F), bar = 50 μm; (G–J), bar = 50 μm.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Summary
Keywords
argyrophilic grain disease, primary age-related tauopathy, tauopathies, tau, seeding, progression, coiled bodies
Citation
Ferrer I, Andrés-Benito P, Sala-Jarque J, Gil V and del Rio JA (2022) Corrigendum: Capacity for Seeding and Spreading of Argyrophilic Grain Disease in a Wild-Type Murine Model; Comparisons With Primary Age-Related Tauopathy. Front. Mol. Neurosci. 15:870475. doi: 10.3389/fnmol.2022.870475
Received
06 February 2022
Accepted
22 February 2022
Published
18 March 2022
Volume
15 - 2022
Edited and reviewed by
Gregg E. Homanics, University of Pittsburgh, United States
Updates
Copyright
© 2022 Ferrer, Andrés-Benito, Sala-Jarque, Gil and del Rio.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Isidro Ferrer 8082ifa@gmail.com
This article was submitted to Methods and Model Organisms, a section of the journal Frontiers in Molecular Neuroscience
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.