The journal retracts the 15 March 2017 article cited above.
Following publication, concerns were raised regarding the integrity of the images in the published figures, with areas of image duplication and manipulation in Figures 1B, 3A. Following a request for raw data, further issues were identified in Figures 5A, B, H. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.
This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The corresponding author Carmela Matrone did not agree to the retraction. Helle Rasmussen agreed to the retraction. The remaining authors did not respond to our correspondence.
Summary
Keywords
APP, Alzheimer's disease, tyrosine phoshorylation, Presenilin mutations, Fyn kinase, Clathrin, clathrin adaptor protein complex
Citation
Frontiers Editorial Office (2023) Retraction: An aberrant phosphorylation of amyloid precursor protein tyrosine regulates its trafficking and the binding to the clathrin endocytic complex in neural stem cells of Alzheimer's disease patients. Front. Mol. Neurosci. 16:1286532. doi: 10.3389/fnmol.2023.1286532
Received
31 August 2023
Accepted
31 August 2023
Published
07 September 2023
Approved by
Robert J. Harvey, University of the Sunshine Coast, Australia
Volume
16 - 2023
Updates
Copyright
© 2023 Frontiers Editorial Office.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Frontiers Editorial Office research.integrity@frontiersin.org
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.