Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Mini Review

Published on 15 Apr 2024

Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?

in Brain Disease Mechanisms

Sandra Kuemper
Andrew G. Cairns
Kristian Birchall
Zhi Yao
Jonathan M. Large

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1370509

7,534 views
7 citations

Original Research

Published on 10 Apr 2024

PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling

in Brain Disease Mechanisms

Guillermo Moya-Alvarado
Xavier Valero-Peña
Alejandro Aguirre-Soto
Fernando J. Bustos
Oscar M. Lazo
Francisca C. Bronfman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1009404

2,950 views
3 citations

Original Research

Published on 10 Apr 2024

A novel pathogenic SLC12A5 missense variant in epilepsy of infancy with migrating focal seizures causes impaired KCC2 chloride extrusion

in Brain Disease Mechanisms

Viivi Järvelä
Mira Hamze
Jonna Komulainen-Ebrahim
Elisa Rahikkala
Johanna Piispala
Mika Kallio
Salla M. Kangas
Tereza Nickl
Marko Huttula
Reetta Hinttala

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1372662

3,346 views
5 citations

Original Research

Published on 05 Apr 2024

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone

in Brain Disease Mechanisms

Shreya H. Dhume
Kayode Balogun
Ambalika Sarkar
Sebastian Acosta
Howard T. J. Mount
Lindsay S. Cahill
John G. Sled
Lena Serghides

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1376681

2,608 views
1 citation

Review

Published on 04 Apr 2024

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

in Brain Disease Mechanisms

Minqi Cai
Qian Zheng
Yiqiang Chen
Siyuan Liu
Huimin Zhu
Bing Bai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379726

2,868 views
2 citations

Correction

Published on 04 Apr 2024

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

in Brain Disease Mechanisms

Basharat Hussain
Cheng Fang
Xiaowen Huang
Ziying Feng
Yuxuan Yao
Yu Wang
Junlei Chang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379436

820 views

Review

Published on 03 Apr 2024

Morphogenetic theory of mental and cognitive disorders: the role of neurotrophic and guidance molecules

in Brain Disease Mechanisms

Alexandra Primak
Kirill Bozov
Kseniya Rubina
Stalik Dzhauari
Elena Neyfeld
Maria Illarionova
Ekaterina Semina
Dmitriy Sheleg
Vsevolod Tkachuk
Maxim Karagyaur

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1361764

2,219 views
1 citation

Mini Review

Published on 28 Mar 2024

Cuproptosis in stroke: focusing on pathogenesis and treatment

in Brain Disease Mechanisms

Liwei Xing
Zhifeng Wang
Zhihui Hao
Pan Pan
Aiming Yang
Jian Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1349123

3,842 views
3 citations

Editorial

Published on 26 Mar 2024

Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia

in Brain Disease Mechanisms

Josué Orlando Ramírez-Jarquín
Angeles C. Tecalco-Cruz
Violeta Gisselle Lopez-Huerta
Uri Nimrod Ramírez-Jarquín

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398127

1,876 views

Review

Published on 22 Mar 2024

Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage

in Brain Disease Mechanisms

Marguerite Jamet
Luc Dupuis
Jose-Luis Gonzalez De Aguilar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1375330

5,004 views

Original Research

Published on 21 Mar 2024

Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation

in Brain Disease Mechanisms

Miho Watanabe
Adya Saran Sinha
Yohei Shinmyo
Atsuo Fukuda

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1373337

3,260 views

Editorial

Published on 18 Mar 2024

Editorial: Proteostasis in central nervous system disorders

in Brain Disease Mechanisms

An Zhou
Fang Bian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1394171

2,246 views

Review

Published on 13 Mar 2024

Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?

in Brain Disease Mechanisms

Antonio d’Amati
Lavinia Bargiacchi
Sabrina Rossi
Andrea Carai
Luca Bertero
Valeria Barresi
Maria Elena Errico
Anna Maria Buccoliero
Sofia Asioli
Gianluca Marucci

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1268038

14,613 views
2 citations

Original Research

Published on 13 Mar 2024

The altered TBI fecal microbiome is stable and functionally distinct

in Brain Disease Mechanisms

Richard B. Pyles
Aaron L. Miller
Randall J. Urban
Melinda Sheffield-Moore
Traver J. Wright
Carrie A. Maxwell
Kathleen M. Randolph
Christopher P. Danesi
Kristen A. McGovern
Jayson Vargas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1341808

4,296 views
7 citations

Original Research

Published on 11 Mar 2024

Activation of nucleus accumbens projections to the ventral tegmental area alters molecular signaling and neurotransmission in the reward system

in Brain Disease Mechanisms

Alaa Khayat
Rami Yaka

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1271654

3,668 views

Review

Published on 11 Mar 2024

A recognition of exosomes as regulators of epigenetic mechanisms in central nervous system diseases

in Brain Disease Mechanisms

Shunxin Hu
Lei Feng
Zhonghong Yang
Xuechen Fan
Haozheng Gao
Tiancai Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1370449

3,265 views
8 citations