Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Original Research

Published on 22 May 2024

Adolescent binge ethanol impacts H3K9me3-occupancy at synaptic genes and the regulation of oligodendrocyte development

in Brain Disease Mechanisms

Emily R. Brocato
Rachel Easter
Alanna Morgan
Meenakshi Kakani
Grace Lee
Jennifer T. Wolstenholme

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1389100

2,965 views

Original Research

Published on 22 May 2024

Spiral ganglion neuron degeneration in aminoglycoside-deafened rats involves innate and adaptive immune responses not requiring complement

in Brain Disease Mechanisms

Benjamin M. Gansemer
Muhammad T. Rahman
Zhenshen Zhang
Steven H. Green

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1389816

4,548 views
5 citations

Original Research

Published on 21 May 2024

Identification of crucial inflammaging related risk factors in multiple sclerosis

in Brain Disease Mechanisms

Mengchu Xu
Huize Wang
Siwei Ren
Bing Wang
Wenyan Yang
Ling Lv
Xianzheng Sha
Wenya Li
Yin Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398665

3,025 views
3 citations

Original Research

Published on 17 May 2024

Dolutegravir induces FOLR1 expression during brain organoid development

in Brain Disease Mechanisms

Carlo Donato Caiaffa
Gabriel Tukeman
Christian Zevallos Delgado
Yogeshwari S. Ambekar
Taye T. Mekonnen
Manmohan Singh
Victoria Rodriguez
Emily Ricco
Daniel Kraushaar
Salavat R. Aglyamov

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1394058

4,503 views
12 citations

Original Research

Published on 17 May 2024

Ahnak in the prefrontal cortex mediates behavioral correlates of stress resilience and rapid antidepressant action in mice

in Brain Disease Mechanisms

Dionnet L. Bhatti
Junghee Jin
Jia Cheng
Kathryn McCabe
Ko-Woon Lee
Clara Berdasco
Yu Young Jeong
Subhash C. Sinha
Yong Kim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1350716

3,970 views
3 citations

Original Research

Published on 14 May 2024

Genetic deletion of zinc transporter ZnT3 induces progressive cognitive deficits in mice by impairing dendritic spine plasticity and glucose metabolism

in Brain Disease Mechanisms

Rui Zong
Xiaoding Zhang
Xiaohui Dong
Guan Liu
Jieyao Zhang
Yiting Gao
Zhongyang Zhang
Yiming Ma
Haixia Gao
Nikita Gamper

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1375925

3,666 views
4 citations

Editorial

Published on 14 May 2024

Editorial: Women in molecular neuroscience

in Brain Disease Mechanisms

Eva Žerovnik

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1422589

1,541 views

Editorial

Published on 08 May 2024

Editorial: 2021 WHO classification of pediatric brain tumors: a final wedding between morphology and molecular biology?

in Brain Disease Mechanisms

Angela Mastronuzzi
Lucia Quaglietta
Elisabetta Schiavello
Andrea Carai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1423298

1,821 views

Mini Review

Published on 02 May 2024

Need of orthogonal approaches in neurological disease modeling in mouse

in Brain Disease Mechanisms

Linda Bossini
Alessandro Sessa

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1399953

1,995 views

Original Research

Published on 30 Apr 2024

Caffeine improves mitochondrial dysfunction in the white matter of neonatal rats with hypoxia-ischemia through deacetylation: a proteomic analysis of lysine acetylation

in Brain Disease Mechanisms

Yajun Zhang
Yuqian Wang
Haiping Dou
Shanshan Wang
Danyang Qu
Xin Peng
Ning Zou
Liu Yang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1394886

6,400 views
10 citations

Correction

Published on 26 Apr 2024

Corrigendum: Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?

in Brain Disease Mechanisms

Antonio d'Amati
Lavinia Bargiacchi
Sabrina Rossi
Andrea Carai
Luca Bertero
Valeria Barresi
Maria Elena Errico
Anna Maria Buccoliero
Sofia Asioli
Gianluca Marucci

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1411360

1,772 views
2 citations

Editorial

Published on 25 Apr 2024

Editorial: The legacy of Dr. Rita Levi-Montalcini: advances in neurotrophic factors in brain disease development and treatment

in Brain Disease Mechanisms

Wei-Jung Chen
Woon-Man Kung
Muh-Shi Lin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1387026

2,008 views

Original Research

Published on 16 Apr 2024

Risk factors and a predictive model for the occurrence of adverse outcomes in patients with new-onset refractory status epilepsy

in Brain Disease Mechanisms

Qiuyan Luo
Rong Lai
Miao Su
Zichao Wu
Huiyu Feng
Hongyan Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1360949

1,947 views
5 citations

Editorial

Published on 15 Apr 2024

Editorial: Molecular and network mechanisms underlying stress resilience

in Brain Disease Mechanisms

Frederick L. Hitti
Brian F. Corbett

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1404375

1,471 views
1 citation

Mini Review

Published on 15 Apr 2024

Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?

in Brain Disease Mechanisms

Sandra Kuemper
Andrew G. Cairns
Kristian Birchall
Zhi Yao
Jonathan M. Large

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1370509

15,139 views
18 citations

Original Research

Published on 10 Apr 2024

PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling

in Brain Disease Mechanisms

Guillermo Moya-Alvarado
Xavier Valero-Peña
Alejandro Aguirre-Soto
Fernando J. Bustos
Oscar M. Lazo
Francisca C. Bronfman

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1009404

5,393 views
11 citations

Original Research

Published on 10 Apr 2024

A novel pathogenic SLC12A5 missense variant in epilepsy of infancy with migrating focal seizures causes impaired KCC2 chloride extrusion

in Brain Disease Mechanisms

Viivi Järvelä
Mira Hamze
Jonna Komulainen-Ebrahim
Elisa Rahikkala
Johanna Piispala
Mika Kallio
Salla M. Kangas
Tereza Nickl
Marko Huttula
Reetta Hinttala

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1372662

5,835 views
10 citations

Original Research

Published on 05 Apr 2024

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone

in Brain Disease Mechanisms

Shreya H. Dhume
Kayode Balogun
Ambalika Sarkar
Sebastian Acosta
Howard T. J. Mount
Lindsay S. Cahill
John G. Sled
Lena Serghides

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1376681

3,907 views
2 citations

Review

Published on 04 Apr 2024

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

in Brain Disease Mechanisms

Minqi Cai
Qian Zheng
Yiqiang Chen
Siyuan Liu
Huimin Zhu
Bing Bai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379726

5,556 views
12 citations

Correction

Published on 04 Apr 2024

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

in Brain Disease Mechanisms

Basharat Hussain
Cheng Fang
Xiaowen Huang
Ziying Feng
Yuxuan Yao
Yu Wang
Junlei Chang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1379436

1,390 views

Review

Published on 03 Apr 2024

Morphogenetic theory of mental and cognitive disorders: the role of neurotrophic and guidance molecules

in Brain Disease Mechanisms

Alexandra Primak
Kirill Bozov
Kseniya Rubina
Stalik Dzhauari
Elena Neyfeld
Maria Illarionova
Ekaterina Semina
Dmitriy Sheleg
Vsevolod Tkachuk
Maxim Karagyaur

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1361764

4,714 views
4 citations

Mini Review

Published on 28 Mar 2024

Cuproptosis in stroke: focusing on pathogenesis and treatment

in Brain Disease Mechanisms

Liwei Xing
Zhifeng Wang
Zhihui Hao
Pan Pan
Aiming Yang
Jian Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1349123

6,119 views
7 citations

Editorial

Published on 26 Mar 2024

Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia

in Brain Disease Mechanisms

Josué Orlando Ramírez-Jarquín
Angeles C. Tecalco-Cruz
Violeta Gisselle Lopez-Huerta
Uri Nimrod Ramírez-Jarquín

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398127

2,439 views

Review

Published on 22 Mar 2024

Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage

in Brain Disease Mechanisms

Marguerite Jamet
Luc Dupuis
Jose-Luis Gonzalez De Aguilar

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1375330

7,761 views
9 citations

1,115 articles

articles

Adolescent binge ethanol impacts H3K9me3-occupancy at synaptic genes and the regulation of oligodendrocyte development

Spiral ganglion neuron degeneration in aminoglycoside-deafened rats involves innate and adaptive immune responses not requiring complement

Identification of crucial inflammaging related risk factors in multiple sclerosis

Dolutegravir induces FOLR1 expression during brain organoid development

Ahnak in the prefrontal cortex mediates behavioral correlates of stress resilience and rapid antidepressant action in mice

Genetic deletion of zinc transporter ZnT3 induces progressive cognitive deficits in mice by impairing dendritic spine plasticity and glucose metabolism

Editorial: Women in molecular neuroscience

Editorial: 2021 WHO classification of pediatric brain tumors: a final wedding between morphology and molecular biology?

Need of orthogonal approaches in neurological disease modeling in mouse

Caffeine improves mitochondrial dysfunction in the white matter of neonatal rats with hypoxia-ischemia through deacetylation: a proteomic analysis of lysine acetylation

Corrigendum: Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?

Editorial: The legacy of Dr. Rita Levi-Montalcini: advances in neurotrophic factors in brain disease development and treatment

Risk factors and a predictive model for the occurrence of adverse outcomes in patients with new-onset refractory status epilepsy

Editorial: Molecular and network mechanisms underlying stress resilience

Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?

PLC-γ-Ca2+ pathway regulates axonal TrkB endocytosis and is required for long-distance propagation of BDNF signaling

A novel pathogenic SLC12A5 missense variant in epilepsy of infancy with migrating focal seizures causes impaired KCC2 chloride extrusion

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone

Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases

Corrigendum: Endothelial β-catenin deficiency causes blood-brain barrier breakdown via enhancing the paracellular and transcellular permeability

Morphogenetic theory of mental and cognitive disorders: the role of neurotrophic and guidance molecules

Cuproptosis in stroke: focusing on pathogenesis and treatment

Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia

Oligodendrocytes in amyotrophic lateral sclerosis and frontotemporal dementia: the new players on stage