Frontiers in Molecular Neuroscience | Pain Mechanisms and Modulators

Original Research

Published on 06 Aug 2024

Coordination between midcingulate cortex and retrosplenial cortex in pain regulation

in Pain Mechanisms and Modulators

Yunya Qiu
Yan-Na Lian
Cheng Wu
Li Liu
Chen Zhang
Xiang-Yao Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1405532

1,528 views
1 citation

Original Research

Published on 17 Jul 2024

Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels

in Pain Mechanisms and Modulators

Gerald Z. Zhuang
William F. Goins
Munal B. Kandel
Marco Marzulli
Mingdi Zhang
Joseph C. Glorioso
Yuan Kang
Alexandra E. Levitt
Konstantinos D. Sarantopoulos
Roy C. Levitt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1416148

2,487 views
1 citation

Mini Review

Published on 26 Jun 2024

Treadmill running on neuropathic pain: via modulation of neuroinflammation

in Pain Mechanisms and Modulators

Wei-Chun He
Shuang-Long Hou
Kai-Bin Wang
Ning Xu
Ke Li
Ting Xiong
Jing Luo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1345864

2,645 views
1 citation

Original Research

Published on 24 Jun 2024

Methods for negating the impact of zinc contamination to allow characterization of positive allosteric modulators of glycine receptors

in Pain Mechanisms and Modulators

Casey I. Gallagher
David P. Bishop
Thomas E. Lockwood
Tristan Rawling
Robert J. Vandenberg

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1392715

1,179 views

Original Research

Published on 22 May 2024

SIRT1-regulated ROS generation activates NMDAR2B phosphorylation to promote central sensitization and allodynia in a male chronic migraine rat model

in Pain Mechanisms and Modulators

Xiaoyan Zhang
Wei Zhang
Yanyun Wang
Yun Zhang
Dunke Zhang
Guangcheng Qin
Jiying Zhou
Lixue Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1387481

2,193 views
3 citations

Original Research

Published on 09 May 2024

GnRH peripherally modulates nociceptor functions, exacerbating mechanical pain

in Pain Mechanisms and Modulators

Haiyan Zheng
Minseok Kim
Chaeun Kim
Yerin Kim
Pyung Sun Cho
Ji Yeon Lim
Hojin Lee
Hye-In Yun
Jungmin Choi
Sun Wook Hwang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1160435

1,909 views

Original Research

Published on 09 May 2024

rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels

in Pain Mechanisms and Modulators

Munal B. Kandel
Gerald Z. Zhuang
William F. Goins
Marco Marzulli
Mingdi Zhang
Joseph C. Glorioso
Yuan Kang
Alexandra E. Levitt
Wai-Meng Kwok
Roy C. Levitt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1398839

2,851 views
4 citations

Original Research

Published on 01 May 2024

Behavioral and pharmacological characterization of planarian nociception

in Pain Mechanisms and Modulators

Guillaume Reho
Yannick Menger
Yannick Goumon
Vincent Lelièvre
Hervé Cadiou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1368009

3,331 views
2 citations

Review

Published on 26 Mar 2024

Acupuncture for radicular pain: a review of analgesic mechanism

in Pain Mechanisms and Modulators

Hong-Lin Li
Yi Zhang
Jian-Wei Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1332876

7,689 views
6 citations

Review

Published on 28 Feb 2024

Advances in understanding migraine pathophysiology: a bench to bedside review of research insights and therapeutics

in Pain Mechanisms and Modulators

Kofi Frimpong-Manson
Yuma T. Ortiz
Lance R. McMahon
Jenny L. Wilkerson

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1355281

15,947 views
10 citations

Original Research

Published on 21 Feb 2024

Machine learning-based evaluation of spontaneous pain and analgesics from cellular calcium signals in the mouse primary somatosensory cortex using explainable features

in Pain Mechanisms and Modulators

Myeong Seong Bak
Haney Park
Heera Yoon
Geehoon Chung
Hyunjin Shin
Soonho Shin
Tai Wan Kim
Kyungjoon Lee
U. Valentin Nägerl
Sang Jeong Kim

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1356453

4,022 views

Original Research

Published on 14 Feb 2024

Tetrandrine alleviates oxaliplatin-induced mechanical allodynia via modulation of inflammation-related genes

in Pain Mechanisms and Modulators

Zhi-Ling Zhang
Zi-Yang Wu
Feng-Yu Liu
Hang-YuChen
Suo-Di Zhai

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1333842

5,101 views
3 citations

Original Research

Published on 06 Feb 2024

Exploring gene signatures and regulatory networks in a rat model of sciatica: implications and validation in neuropathic pain

in Pain Mechanisms and Modulators

Mu Xu
Zhijian Wang
Gang Xu
Mengye Zhu
Daying Zhang
Yi Yan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1261217

1,988 views

Mini Review

Published on 30 Jan 2024

Mechanisms of transcranial direct current stimulation (tDCS) for pain in patients with fibromyalgia syndrome

in Pain Mechanisms and Modulators

Shan Wang
Shu-Hao Du
Xue-Qiang Wang
Jun-Yan Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1269636

6,014 views
2 citations

Review

Published on 22 Dec 2023

Molecular mechanisms of pain in acute pancreatitis: recent basic research advances and therapeutic implications

in Pain Mechanisms and Modulators

Yongzi Wu
Chenxia Han
Rong Luo
Wenhao Cai
Qing Xia
Ruotian Jiang
Pawel E. Ferdek
Tingting Liu
Wei Huang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1331438

6,561 views
6 citations

Original Research

Published on 07 Dec 2023

Spinal GABA transporter 1 contributes to evoked-pain related behavior but not resting pain after incision injury

in Pain Mechanisms and Modulators

Bruno Pradier
Daniel Segelcke
Sylvia Reichl
P. K. Zahn
E. M. Pogatzki-Zahn

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2023.1282151

1,899 views
4 citations