ORIGINAL RESEARCH article
Front. Nanotechnol.
Sec. Nanomaterials
Synthesis and Characterization of Co-and Ni-based MOFs, methylene blue adsorption studies and their Anti Microbiological activity
Provisionally accepted
- 1Mahatma Gandhi University, Nalgonda, India
- 2Institut Jozef Stefan, Ljubljana, Slovenia
- 3Isosphere Biosciences Pvt Ltd, Secundrabad, India
- 4Gandhi Institute of Technology and Management - Hyderabad Campus, Hyderabad, India
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This paper presents mixed-ligand frameworks, including MOF@1 [Co(H2BDC-N2H3) (Phen), MOF@2 [Co(H2BDC-N2H3) (Phen)@SA], MOF@3 [Ni(N2H3-BDC) (Phen)], and MOF@4 [Ni(N2H3-BDC) (Phen)@SA] composites, synthesized using a one pot solvothermal method. The composites were investigated using SEM, FT-IR, EDS, PXRD and BET. The antibacterial activity of the composite MOFs was tested on Staphylococcus aureus and E. coli. The MOF@3 showed an exceptional antibacterial activity of 16mm at a concentration of 100 µg. The Agar well diffusion method was used to determine antifungal characteristics of the compound, with the Candida albicans strain used as the standard. The compound with Sodium Alginate displayed a zone of inhibition of 15mm, while MOF@ demonstrated a high level of anti-fungal activity with 17mm. The adsorption capabilities of the MOFs for Methylene Blue (MB) dye were investigated at room temperature. MOF@4 showed the highest adsorption capability, with a maximum capacity of 18.03 mg/g for MOF@1, 25.16 mg/g for MOF@2, 61.3 mg/g for MOF@3, and 98.47 mg/g for MOF@4. The research aims to provide light on the possible applications of mixed-ligand MOFs, specifically MOF@4, in biological and environmental research, including antibacterial treatments and dye remediation applications. The antibacterial treatments and dye remediation applications are included in these applications. The foundation for subsequent research that will be carried out with the purpose of improving MOF structures for applications that require a wide variety of functionalities has been laid by these discoveries.
Keywords: Solvothermal method, Mixed ligand cobalt MOFs, Mixed ligand Nickel MOFs, 1,10–Phenanthroline, Antimicrobial activity, Antifungal activity
Received: 25 Jul 2025; Accepted: 18 Nov 2025.
Copyright: © 2025 P, Yarasani, Junkar, Tentu, Ganji and K. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ita Junkar, ita.junkar@ijs.si
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