Frontiers in Physiology | Computational Physiology and Medicine

Original Research

Published on 11 Apr 2025

Hemidiaphragm work in large pleural effusion and its insignificant impact on blood gases: a new insight based on in silico study

in Computational Physiology and Medicine

Tomasz Gólczewski
Anna M. Stecka
Elżbieta M. Grabczak
Marcin Michnikowski
Monika Zielińska-Krawczyk
Rafał Krenke

Frontiers in Physiology

doi 10.3389/fphys.2025.1539781

1,555 views
1 citation

Opinion

Published on 09 Apr 2025

The prophet’s rite of passage – pitfalls in evaluating real-time prediction in medicine

in Computational Physiology and Medicine

Noam Keidar
Yael Yaniv

Frontiers in Physiology

doi 10.3389/fphys.2025.1569008

1,153 views

Original Research

Published on 01 Apr 2025

A multi-modal deep learning approach for stress detection using physiological signals: integrating time and frequency domain features

in Computational Physiology and Medicine

Jun-Zhi Xiang
Qin-Yong Wang
Zhi-Bin Fang
James A. Esquivel
Zhi-Xian Su

Frontiers in Physiology

doi 10.3389/fphys.2025.1584299

11,062 views
23 citations

Original Research

Published on 26 Mar 2025

Interpretive machine learning predicts short-term mortality risk in elderly sepsis patients

in Computational Physiology and Medicine

Xing-Yu Zhu
Zhi-Meng Jiang
Xiao‐ Li
Zi-Wen Lv
Jian-Wei Tian
Fei-Fei Su

Frontiers in Physiology

doi 10.3389/fphys.2025.1549138

3,374 views
1 citation

Original Research

Published on 26 Mar 2025

Design of a hybrid AI network circuit for epilepsy detection with 97.5% accuracy and low cost-latency

in Computational Physiology and Medicine

Liufang Sheng
Xuanxu Chen
Yuejun Zhang
Ke Yan
Junping Chen
Zhikang Chen
Hanyu Shi
Yi Gong

Frontiers in Physiology

doi 10.3389/fphys.2025.1514883

2,111 views
1 citation

Original Research

Published on 25 Mar 2025

Shape of the mitral annulus in normal individuals and dilated cardiomyopathies: computational modeling insights into leaflet stress distribution

in Computational Physiology and Medicine

Salvatore Pasta
Eluisa La Franca
Fabrizio Crascì
Giovanni Gentile
Manlio Cipriani
Francesco Fulvio Faletra

Frontiers in Physiology

doi 10.3389/fphys.2025.1532972

1,938 views

Original Research

Published on 24 Mar 2025

Cross-sectional study on smoking types and stroke risk: development of a predictive model for identifying stroke risk

in Computational Physiology and Medicine

Chao Ding
Minjia Yuan
Jiwei Cheng
Junkai Wen

Frontiers in Physiology

doi 10.3389/fphys.2025.1528910

5,079 views
3 citations

Original Research

Published on 18 Mar 2025

A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis

in Computational Physiology and Medicine

Xiaoyu Yin
Sophie Adelaars
Elisabetta Peri
Eduard Pelssers
Jaap Den Toonder
Arthur Bouwman
Daan Van de Kerkhof
Massimo Mischi

Frontiers in Physiology

doi 10.3389/fphys.2025.1547117

2,456 views
1 citation

Original Research

Published on 18 Mar 2025

Cnidaria herd optimized fuzzy C-means clustering enabled deep learning model for lung nodule detection

in Computational Physiology and Medicine

R. Hari Prasada Rao
Agam Das Goswami

Frontiers in Physiology

doi 10.3389/fphys.2025.1511716

1,861 views
1 citation

Review

Published on 13 Mar 2025

Artificial intelligence optimizes the standardized diagnosis and treatment of chronic sinusitis

in Computational Physiology and Medicine

Yang-Yang Liu
Shao-Peng Jiang
Ying-Bin Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1522090

5,345 views
3 citations

Original Research

Published on 12 Mar 2025

Multimodal diagnosis of Alzheimer’s disease based on resting-state electroencephalography and structural magnetic resonance imaging

in Computational Physiology and Medicine

Junxiu Liu
Shangxiao Wu
Qiang Fu
Xiwen Luo
Yuling Luo
Sheng Qin
Yiting Huang
Zhaohui Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1515881

4,199 views
3 citations

Original Research

Published on 12 Mar 2025

A multi-modal deep learning solution for precise pneumonia diagnosis: the PneumoFusion-Net model

in Computational Physiology and Medicine

Yujie Wang
Can Liu
Yinghan Fan
Chenyue Niu
Wanyun Huang
Yixuan Pan
Jingze Li
Yilin Wang
Jun Li

Frontiers in Physiology

doi 10.3389/fphys.2025.1512835

5,503 views
3 citations

Original Research

Published on 07 Mar 2025

Multimodal deep learning with MUF-net for noninvasive WHO/ISUP grading of renal cell carcinoma using CEUS and B-mode ultrasound

in Computational Physiology and Medicine

Yixin Zhu
Ji Wu
Qiongxian Long
Yan Li
Hao Luo
Lu Pang
Lin Zhu
Hui Luo

Frontiers in Physiology

doi 10.3389/fphys.2025.1558997

2,690 views
1 citation

Original Research

Published on 04 Mar 2025

Prediction of time averaged wall shear stress distribution in coronary arteries’ bifurcation varying in morphological features via deep learning

in Computational Physiology and Medicine

Mohammad Hossein Sarkhosh
Hadis Edrisnia
Mohammad Reza Raveshi
Mahkame Sharbatdar

Frontiers in Physiology

doi 10.3389/fphys.2025.1518732

3,146 views
4 citations

Original Research

Published on 25 Feb 2025

An emotion recognition method based on frequency-domain features of PPG

in Computational Physiology and Medicine

Zhibin Zhu
Xuanyi Wang
Yifei Xu
Wanlin Chen
Jing Zheng
Shulin Chen
Hang Chen

Frontiers in Physiology

doi 10.3389/fphys.2025.1486763

4,005 views
5 citations

Original Research

Published on 24 Feb 2025

In silico oncology: a mechanistic multiscale model of clinical prostate cancer response to external radiation therapy as the core of a digital (virtual) twin. Sensitivity analysis and a clinical adaptation approach

in Computational Physiology and Medicine

Georgios Stamatakos
Eleni Kolokotroni
Foteini Panagiotidou
Stamatia Tsampa
Christos Kyroudis
Simon Spohn
Anca-Ligia Grosu
Dimos Baltas
Constantinos Zamboglou
Ilias Sachpazidis

Frontiers in Physiology

doi 10.3389/fphys.2025.1434739

3,925 views
6 citations

Original Research

Published on 19 Feb 2025

Web-based machine learning application for interpretable prediction of prolonged length of stay after lumbar spinal stenosis surgery: a retrospective cohort study with explainable AI

in Computational Physiology and Medicine

Paierhati Yasheng
Alimujiang Yusufu
Yasenjiang Yimiti
Haopeng Luan
Cong Peng
Xinghua Song

Frontiers in Physiology

doi 10.3389/fphys.2025.1542240

2,655 views
4 citations

Original Research

Published on 12 Feb 2025

A four-compartment controller model of muscle fatigue for static and dynamic tasks

in Computational Physiology and Medicine

James Yang
Ritwik Rakshit
Shuvrodeb Barman
Yujiang Xiang

Frontiers in Physiology

doi 10.3389/fphys.2025.1518847

2,407 views
3 citations

Editorial

Published on 05 Feb 2025

Editorial: Integrating machine learning with physics-based modeling of physiological systems

in Computational Physiology and Medicine

Jae H. Lee
Hao Gao
Michael Döllinger

Frontiers in Physiology

doi 10.3389/fphys.2025.1562750

2,804 views
3 citations

Original Research

Published on 23 Jan 2025

Comparison and verification of detection accuracy for late deceleration with and without uterine contractions signals using convolutional neural networks

in Computational Physiology and Medicine

Ikumi Sato
Yuta Hirono
Eiri Shima
Hiroto Yamamoto
Kousuke Yoshihara
Chiharu Kai
Akifumi Yoshida
Fumikage Uchida
Naoki Kodama
Satoshi Kasai

Frontiers in Physiology

doi 10.3389/fphys.2025.1525266

2,329 views
3 citations

Correction

Published on 22 Jan 2025

Corrigendum: Computational study of transcatheter aortic valve replacement based on patient-specific models—rapid surgical planning for self-expanding valves

in Computational Physiology and Medicine

Zhuangyuan Meng
Haishan Zhang
Yunhan Cai
Yuan Gao
Changbin Liang
Jun Wang
Xin Chen
Liang Guo
ShengZhang Wang

Frontiers in Physiology

doi 10.3389/fphys.2025.1541483

1,152 views

Original Research

Published on 07 Jan 2025

A combined diagnostic model including middle rectal artery visualization for predicting lateral lymph node metastasis in rectal cancer

in Computational Physiology and Medicine

Ning Wang
Yiping Li
Kun Lu
Kaikai Wei
Shize Jia
Shuhong Fan
Donglin Ren
Yuanji Fu
Zhimin Liu

Frontiers in Physiology

doi 10.3389/fphys.2024.1444897

1,574 views

Review

Published on 03 Jan 2025

Non-invasive ML methods for diagnosis of congenital heart disease associated with pulmonary arterial hypertension

in Computational Physiology and Medicine

Yuyang Gao
Pengyue Ma
Jiahua Pan
Hongbo Yang
Tao Guo
Weilian Wang

Frontiers in Physiology

doi 10.3389/fphys.2024.1502725

2,487 views
2 citations

Editorial

Published on 03 Jan 2025

Editorial: Hemodynamic parameters and cardiovascular changes

in Computational Physiology and Medicine

Tania Pereira
Kais Gadhoumi
Ran Xiao

Frontiers in Physiology

doi 10.3389/fphys.2024.1538859

1,672 views
1 citation

1,170 articles

articles

Hemidiaphragm work in large pleural effusion and its insignificant impact on blood gases: a new insight based on in silico study

The prophet’s rite of passage – pitfalls in evaluating real-time prediction in medicine

A multi-modal deep learning approach for stress detection using physiological signals: integrating time and frequency domain features

Interpretive machine learning predicts short-term mortality risk in elderly sepsis patients

Design of a hybrid AI network circuit for epilepsy detection with 97.5% accuracy and low cost-latency

Shape of the mitral annulus in normal individuals and dilated cardiomyopathies: computational modeling insights into leaflet stress distribution

Cross-sectional study on smoking types and stroke risk: development of a predictive model for identifying stroke risk

A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis

Cnidaria herd optimized fuzzy C-means clustering enabled deep learning model for lung nodule detection

Artificial intelligence optimizes the standardized diagnosis and treatment of chronic sinusitis

Multimodal diagnosis of Alzheimer’s disease based on resting-state electroencephalography and structural magnetic resonance imaging

A multi-modal deep learning solution for precise pneumonia diagnosis: the PneumoFusion-Net model

Multimodal deep learning with MUF-net for noninvasive WHO/ISUP grading of renal cell carcinoma using CEUS and B-mode ultrasound

Prediction of time averaged wall shear stress distribution in coronary arteries’ bifurcation varying in morphological features via deep learning

An emotion recognition method based on frequency-domain features of PPG

In silico oncology: a mechanistic multiscale model of clinical prostate cancer response to external radiation therapy as the core of a digital (virtual) twin. Sensitivity analysis and a clinical adaptation approach

Web-based machine learning application for interpretable prediction of prolonged length of stay after lumbar spinal stenosis surgery: a retrospective cohort study with explainable AI

A four-compartment controller model of muscle fatigue for static and dynamic tasks

Editorial: Integrating machine learning with physics-based modeling of physiological systems

Comparison and verification of detection accuracy for late deceleration with and without uterine contractions signals using convolutional neural networks

Corrigendum: Computational study of transcatheter aortic valve replacement based on patient-specific models—rapid surgical planning for self-expanding valves

A combined diagnostic model including middle rectal artery visualization for predicting lateral lymph node metastasis in rectal cancer

Non-invasive ML methods for diagnosis of congenital heart disease associated with pulmonary arterial hypertension

Editorial: Hemodynamic parameters and cardiovascular changes