Frontiers in Physiology | Integrative Physiology

Original Research

Published on 14 May 2026

TPM-like manipulations exerted an antidepressant effect and regulated amino acid metabolism and GHR/IGF-1 pathway in the liver in adolescent female CUMS rats

in Integrative Physiology

Shaoyun Zhao
Jiaxuan Gong
Rong Wu
Ying Xiong
Yun Gu
Yuhang Wang
Zhixiu Song

Frontiers in Physiology

doi 10.3389/fphys.2026.1752608

238 views

Review

Published on 11 May 2026

Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies

in Integrative Physiology

Adelaide L. Cagle
Afton K. Limberg
Amritha Anup
Aleyna E. La Croix
Katherine R. Hixon

Frontiers in Physiology

doi 10.3389/fphys.2026.1811508

384 views

Systematic Review

Published on 11 May 2026

Effect of acupuncture on monoaminergic neurotransmitters in animal models of vascular dementia: a preclinical systematic review and meta-analysis

in Integrative Physiology

Lixiang Gan
Yuqing Fan
Dongmin Liu
Jialing Zheng
Jize Han
Chuyu Deng
Xiaorong Tang
Nenggui Xu
Zhennan Wu

Frontiers in Physiology

doi 10.3389/fphys.2026.1811438

334 views

Original Research

Published on 08 May 2026

A study on brain waves with electroencephalogram through the appreciation of virtual reality K-pop: a revised analysis with multiple comparison corrections

in Integrative Physiology

Taeseung Park
Hyunsoo Kim
Deok Su Yoo

Frontiers in Physiology

doi 10.3389/fphys.2026.1808008

406 views

Review

Published on 08 May 2026

Is there a link between fascia and cancer? From potential mechanisms to future treatment options

in Integrative Physiology

Stephanie Otto
Werner Klingler

Frontiers in Physiology

doi 10.3389/fphys.2026.1741526

865 views

Systematic Review

Published on 07 May 2026

Effectiveness of non-pharmacological therapies in complementary and alternative medicine on improving fatigue levels, oxidative stress, inflammation, and endocrine levels in animal models of chronic fatigue-like conditions: a systematic review and network meta-analysis

in Integrative Physiology

Shumeng Ren
Jingyuan Wei
Shan Zhao
Linghua Li
Jingshi Zhang
Chaoqun Yan
Jun Wang

Frontiers in Physiology

doi 10.3389/fphys.2026.1807587

400 views

Correction

Published on 05 May 2026

Correction: Exercise and the hepatic sirtuin network: rethinking the research focus on SIRT1, SIRT3, and SIRT6

in Integrative Physiology

Jun Woo Kwon

Frontiers in Physiology

doi 10.3389/fphys.2026.1851497

360 views

Perspective

Accepted on 04 May 2026

Rethinking Biological Resilience of Older Adults Under Climate Change: An Integrative Perspective from Planetary Health and Cultural Ethics

in Integrative Physiology

Chengmeng Zhang
Yilin Liu
Haoyu Suo
Gong Chen

Frontiers in Physiology

153 views

Review

Published on 30 Apr 2026

Physiological responses and adaptive mechanisms of amphibians and reptiles to multiple interacting environmental stressors: an integrative review

in Integrative Physiology

Muammer Kurnaz

Frontiers in Physiology

doi 10.3389/fphys.2026.1785483

787 views

Original Research

Accepted on 29 Apr 2026

Quantifying Changes in Triaxial Seismocardiography Variability due to Sub-Optimal Volume Status

in Integrative Physiology

Gabriela Isabel Cestero
Zeineb Bouzid
Afra Nawar
Cem Okan Yaldiz
Demet Tangolar
Zhongjun J Wu
Jin-Oh Hahn
Omer Inan

Frontiers in Physiology

200 views

Review

Published on 27 Apr 2026

25 years of applying the 3Rs principles in safety pharmacology: success stories and future perspectives

in Integrative Physiology

Katayoun Derakhchan
Kimberly Rockley
Matthias Gossmann
Raafat Fares
Eric Delpy
Yasunari Kanda
Elisa Passini
Colleen M. Pike
Janette Turner
Annie Delaunois

Frontiers in Physiology

doi 10.3389/fphys.2026.1813708

1,205 views

Original Research

Published on 23 Apr 2026

Changes in cardio-respiratory-vascular coupling dynamics across altitude gradients: a shift from linear synchrony to nonlinear complexity

in Integrative Physiology

Hongyun Liu
Shijing Wu
Ping Zhan
Xiaohua Yu
Yiming Kuang
Yi Han
Hongyue Zu
Guojing Wang
Weidong Wang

Frontiers in Physiology

doi 10.3389/fphys.2026.1818880

561 views

Hypothesis and Theory

Accepted on 20 Apr 2026

Fibrosis versus Plasticity: A Tensegrity-Based Framework for Acupuncture as an Exploratory Modulator of Tissue Recovery

in Integrative Physiology

Alejandro Carballo

Frontiers in Physiology

229 views

Perspective

Published on 15 Apr 2026

Bridging physiology and psychology: a new framework for teaching homeostasis

in Integrative Physiology

Suzan Kamel-ElSayed
Nermien E. Waly
Changiz Mohiyeddini

Frontiers in Physiology

doi 10.3389/fphys.2026.1808472

649 views

Perspective

Published on 13 Apr 2026

High intellectual ability and the gut-brain-sex steroids axis: a perspective on cognitive and emotional diversity

in Integrative Physiology

Ítalo M. Urrutia
Nicolás Plaza
Felipe Moraga
Constanza Griffiths-Sanhueza
Diliana Pérez-Reytor
Eduardo Karahanian
Sebastián Ramírez-Araya
Ana Kinkead
María Paz Gómez
Katherine Garcia

Frontiers in Physiology

doi 10.3389/fphys.2026.1791778

686 views

Original Research

Published on 13 Apr 2026

Efficacy and safety of gabapentinoid combination therapy versus monotherapy for the treatment of neuropathic pain

in Integrative Physiology

Dandan Li
Yang He
Zhiqiang Fan
Zhen Chen
Guiming Deng
Linqi Ouyang

Frontiers in Physiology

doi 10.3389/fphys.2026.1802999

613 views

Original Research

Published on 10 Apr 2026

Molecular mechanism of Danshen injection in treating endometrial fibrosis induced by intrauterine adhesions via the LAMC2-CD44-TGF-β1-SMAD2/3 signaling pathway

in Integrative Physiology

Sisi Tang
Renzhi Hu
Shuangyan Weng
Mei Luo

Frontiers in Physiology

doi 10.3389/fphys.2026.1794215

525 views

Review

Published on 27 Mar 2026

Myofascial release and fascial-targeted mechanical interventions in musculoskeletal rehabilitation: mechanisms, modalities, and integrative physiology

in Integrative Physiology

Yuqing Gao
Dongxu Gao

Frontiers in Physiology

doi 10.3389/fphys.2026.1801306

2,176 views

Review

Published on 27 Mar 2026

The fascial-interstitial system and the sanjiao-mocou system: an analogy-based hypothesis for the anatomical basis of meridian pathways

in Integrative Physiology

Yu Xia
Yuxin Jia
Hui Qu
Qianxue Wei
Limei Yan
Xiuqin Li

Frontiers in Physiology

doi 10.3389/fphys.2026.1795656

1,465 views

Original Research

Published on 19 Mar 2026

Short-term cigarette smoke exposure aggravates oxidative stress and airway inflammation induced by lipopolysaccharides

in Integrative Physiology

Ziyao Liang
Zhihang Liu
Wenchao Pan
Long Fan
Jingyu Quan
Lin Lin
Lei Wu
Xuhua Yu

Frontiers in Physiology

doi 10.3389/fphys.2026.1788828

632 views

Original Research

Published on 11 Mar 2026

Impact of cricothyroid membrane puncture anesthesia on elderly patients undergoing endotracheal intubation after anesthesia induction: a clinical study

in Integrative Physiology

Yanbing Wang
Hongchuan Zhao
Yanjiao Liang
Xiaoli Li
Xiao Bi
Hao Lian

Frontiers in Physiology

doi 10.3389/fphys.2025.1600369

579 views

Conceptual Analysis

Published on 02 Mar 2026

How should we teach homeostasis? Filling the gaps and envisioning the future

in Integrative Physiology

Serena Y. Kuang
Akshata R. Naik

Frontiers in Physiology

doi 10.3389/fphys.2026.1784015

699 views

Original Research

Published on 25 Feb 2026

mRNA expression profiling and pathway analysis of chronic intermittent hypoxia–induced pancreatic injury in ob/ob mice

in Integrative Physiology

Yaopeng Guo
Shengquan Huang
Jiayi Lin
Chaowei Li
Ruhai Lin
Qingshi Chen

Frontiers in Physiology

doi 10.3389/fphys.2026.1740223

418 views

Editorial

Published on 25 Feb 2026

Editorial: Exploring the physiological and molecular benefits of physical exercise in cardiovascular diseases

in Integrative Physiology

Alex Cleber Improta-Caria
Roque Aras Júnior

Frontiers in Physiology

doi 10.3389/fphys.2026.1809357

529 views

1,775 articles

articles

TPM-like manipulations exerted an antidepressant effect and regulated amino acid metabolism and GHR/IGF-1 pathway in the liver in adolescent female CUMS rats

Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies

Effect of acupuncture on monoaminergic neurotransmitters in animal models of vascular dementia: a preclinical systematic review and meta-analysis

A study on brain waves with electroencephalogram through the appreciation of virtual reality K-pop: a revised analysis with multiple comparison corrections

Is there a link between fascia and cancer? From potential mechanisms to future treatment options

Effectiveness of non-pharmacological therapies in complementary and alternative medicine on improving fatigue levels, oxidative stress, inflammation, and endocrine levels in animal models of chronic fatigue-like conditions: a systematic review and network meta-analysis

Correction: Exercise and the hepatic sirtuin network: rethinking the research focus on SIRT1, SIRT3, and SIRT6

Rethinking Biological Resilience of Older Adults Under Climate Change: An Integrative Perspective from Planetary Health and Cultural Ethics

Physiological responses and adaptive mechanisms of amphibians and reptiles to multiple interacting environmental stressors: an integrative review

Quantifying Changes in Triaxial Seismocardiography Variability due to Sub-Optimal Volume Status

25 years of applying the 3Rs principles in safety pharmacology: success stories and future perspectives

Changes in cardio-respiratory-vascular coupling dynamics across altitude gradients: a shift from linear synchrony to nonlinear complexity

Fibrosis versus Plasticity: A Tensegrity-Based Framework for Acupuncture as an Exploratory Modulator of Tissue Recovery

Bridging physiology and psychology: a new framework for teaching homeostasis

High intellectual ability and the gut-brain-sex steroids axis: a perspective on cognitive and emotional diversity

Efficacy and safety of gabapentinoid combination therapy versus monotherapy for the treatment of neuropathic pain

Molecular mechanism of Danshen injection in treating endometrial fibrosis induced by intrauterine adhesions via the LAMC2-CD44-TGF-β1-SMAD2/3 signaling pathway

Myofascial release and fascial-targeted mechanical interventions in musculoskeletal rehabilitation: mechanisms, modalities, and integrative physiology

The fascial-interstitial system and the sanjiao-mocou system: an analogy-based hypothesis for the anatomical basis of meridian pathways

Short-term cigarette smoke exposure aggravates oxidative stress and airway inflammation induced by lipopolysaccharides

Impact of cricothyroid membrane puncture anesthesia on elderly patients undergoing endotracheal intubation after anesthesia induction: a clinical study

How should we teach homeostasis? Filling the gaps and envisioning the future

mRNA expression profiling and pathway analysis of chronic intermittent hypoxia–induced pancreatic injury in ob/ob mice

Editorial: Exploring the physiological and molecular benefits of physical exercise in cardiovascular diseases