ORIGINAL RESEARCH article
Front. Plant Physiol.
Sec. Plant Morphogenesis and Evolution
Volume 3 - 2025 | doi: 10.3389/fphgy.2025.1657264
MYB4 and HY5 Integrate Light and Cytokinin Signaling Pathways during Arabidopsis seedling development
Provisionally accepted
- National Institute of Technology, Durgapur, Durgapur, India
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Arabidopsis seedling growth is regulated by integration of various environmental and hormonal signals. While the interactions between light and cytokinin signaling pathways have been studied, the molecular mechanism by which their interaction regulate hypocotyl elongation remain unclear. In this study, we demonstrate that MYB4, a positive regulator of photomorphogenesis, physically interacts with HY5 and attenuates HY5-mediated regulation of MYB4. The expression of MYB4 is induced by different wavelengths of light and it genetically interacts with HY5 to regulate hypocotyl length during light-mediated seedling development. The MYB4 and HY5 mediated regulation of hypocotyl length is altered upon cytokinin treatment in a light intensitydependent manner. Furthermore, on contrary to the light signals, cytokinin suppresses MYB4 expression. MYB4 together with HY5 regulates the expression of the key genes such as ABCG14, ARR4, and CHS involved in cytokinin signaling pathway. Taken together, this study highlights how the HY5-MYB4 module integrates light and cytokinin signals to fine-tune Arabidopsis seedling development.
Keywords: MYB4, HY5, Photomorphogenesis, Cytokinin, seedling development
Received: 01 Jul 2025; Accepted: 01 Sep 2025.
Copyright: © 2025 Pal, Basu and Chattopadhyay. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Sudip Chattopadhyay, National Institute of Technology, Durgapur, Durgapur, India
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