ORIGINAL RESEARCH article
Front. Stroke
Sec. Population Health and Risk Factors of Stroke
The Global Burden of Stroke and Risk Factors for Population Aged 65 and Above Worldwide from 1990 to 2021: A Systematic Analysis of the Global Burden of Disease Study 2021
Provisionally accepted
- The First Affiliated Hospital of Jiamusi University, Jiamusi, China
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Stroke is one of the leading causes of disability and death globally, and the prevalence of stroke shows an upward trend among older adults aged ≥65 years. However, comprehensive assessments of stroke burden by age group, gender, and risk factors at the global, regional, and national levels are limited.A Systematic Analysis of GBD 2021 Data: Investigating Disease Burden, Trends, and Risk Factors of Stroke Among Adults Aged ≥65 Years by Age Subgroups and Gender at Global, Regional, and National Levels (1990—2021).Extracted and processed from the Global Burden of Disease (GBD) data from 1990 to 2021, age-standardized rates of stroke, including prevalence, incidence, mortality, and disability-adjusted life years (DALYs), were obtained for older adults aged 65 and above across 21 regions and 204 countries. These data were then used to determine the disease burden of stroke among individuals aged 65 and above at the global, regional, and national levels. Descriptive analysis, relative change rate (Cases Change), and average annual percentage change (AAPC) were used to interpret the trends.Results and Conclusions are too long to fit.
Keywords: Stroke, Global Burden of Disease study, Mortality, Disability, Disability-adjusted life-years (DALYs), Incidence, Prevalence, vital registration
Received: 03 Jul 2025; Accepted: 10 Sep 2025.
Copyright: © 2025 Yang, Li, meng, wang, yang and liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
guangyuan yang, ygy665@126.com
mingyuan liu, 13846194865@qq.com
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