About this Research Topic
Carbohydrates are the most complex biological macromolecules in the world, so there are many types of carbohydrate-active enzymes involved in the synthesis and degradation of carbohydrates. According to the CAZy database , these enzymes have been classified into more than 340 families.
Carbohydrate-active enzymes are always an international research hotspot because of their important physiological functions in energy metabolism, structural support and signal transduction in life. At the same time, carbohydrate-active enzymes have a wide range of uses, including as biocatalysts to synthesis or degradation of carbohydrates, as diagnostic markers, directly as drugs and as drug targets. Inhibitors of these enzymes can modulate the activity of the above enzymes in vitro and in vivo , and thus can be used as drugs in the fields of medicine (e.g. acarbose and zanamivir), agriculture, forestry, and public health.
This Research Topic aims to explore the latest research into carbohydrate-activ enzymes with a focus on the:
• Expression, purification and characterization of carbohydrate-active enzymes.
• Structure and function relationship of carbohydrate-active enzymes.
• Application of carbohydrate-active enzymes as biocatalyst, biomarker or drugs.
• Engineering of carbohydrate-active enzymes.
• Discovery of inhibitors of carbohydrate-active enzymes.
• Application of inhibitors of carbohydrate-active enzymes.
Keywords: Carbohydrates, Enzyme, Inhibitor, Biocatalyst, Structure
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