Damage of the auditory system associated with many factors, including genetic deficiency, aging, medication, noise, infection, and many other environmental factors. The mammalian inner ear is a highly differentiated organ, especially the hair cells and spiral neurons that have no ability to regenerate. Therefore, excessive damage to the inner ear cells will lead to permanent hearing loss. So far, there are limited clinical approaches to prevent and treat deafness due to the unique nature of the inner ear structure and cells.
Therefore, in-depth research on the mechanism of the occurrence and development of sensorineural hearing loss is urgently required. Restoring the structure and function of auditory organs with new technologies and methods will be a key research direction in this field. With the advances of new technologies and methods such as gene therapy, stem cell therapy, biomaterials, and tissue engineering, we hope that more studies can provide the theoretical and experimental basis for the prevention and treatment of sensorineural hearing loss, and basic research findings can eventually be translated into therapeutic applications.
This Research Topic aims to encourage researchers to investigate the mechanisms of genetic, noise, medication, and aging-related sensorineural deafness and other types of deafness. Original research articles on the pathogenesis of sensorineural deafness, as well as original research articles and reviews on novel technologies and methods in the field of sensorineural deafness prevention and treatment, are both welcome. With this research topic, we aim to show the latest research in the auditory neuroscience field, focusing on:
- Examining the role of neurons, hair cells, and other cells in the development and degeneration of the central and peripheral auditory systems.
- Studying the regeneration of spiral ganglion neurons and hair cells.
- Developing novel therapeutic approaches for treating sensorineural deafness.
- Exploring the application of novel research technologies and materials in auditory research.
Keywords: Sensorineural Deafness, Hearing Loss, Hair Cell, Neuron, Auditory Organ
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
